Tag: "neurodegenerative" at medical news
Chemical present in clear plastics can impair learning and cause disease
...n, leading to learning disabilities and agerelated neurodegenerative
diseases, according to Yale researchers and collea... hippocampal function and contribute to agerelated neurodegenerative
diseases such as Alzheimer's disease, in which hippocampal function is impaired. About two billion p...
UT Southwestern lead site for study of a new multiple sclerosis drug
...f MS affects about 15 percent of patients with the neurodegenerative
disease."There really hasn't been a lot of research or treatment options for patients with this form of MS," said Dr. Kathleen Hawker, assistant professor of neurology, who is heading up the clinical investigation. UT Southwestern researchers are tes...
Antibiotic might fight HIV-induced neurological problems
...oteins -- MCP-1 and p38 -- implicated in damage in neurodegenerative
diseases. The MCP-1 protein, when secreted from brain cells under attack from HIV or SIV, attracts infection-fighting cells known as macrophages, which then enter the brain. The influx of these cells contributes to swelling and inflammation known as ...
Dietary vitamin E may lower risk of Parkinson's disease
...an be made, state the authors. PD is a progressive neurodegenerative
disease with unknown cause. PD is likely to result from the combined effects of multiple factors including ageing, genetic predisposition, and environmental exposures. Some studies suggest that diets rich in vitamin E are protective against PD; other...
Red delicious, Northern Spy apples have most antioxidants, chemists find
...aging process associated with Alzheimers and other neurodegenerative
disorders. This study was published in the December 1, 2004, issue of the Journal of Agriculture and Food Chemistry. Heart disease. Antioxidants found in apple extracts could potentially lower "bad" cholesterol (low density lipoprotein, or LDL)...
Harvard Medical School and Project A.L.S. join forces to target ALS research
...th an ultimate objective of reducing the impact of neurodegenerative
disease, such as ALS. "At the Harvard Center for N...ieve that the fastest way to develop therapies for neurodegenerative
diseases is through collaborative translational research," said HCNR director, Dr. Adrian J. Ivinson...
Variant prion protein causes infection but no symptoms
...k provides novel insights into how prion and other neurodegenerative
diseases develop and it provides tantalizing clues as to how we might delay or even prevent such diseases by preventing certain cellular interactions," notes NIAID Director Anthony S. Fauci, M.D.A paper describing the research was released online tod...
Nature publication reports key links between mechanisms of aging and metabolic disorders
...s including cancers, cardiovascular, metabolic and neurodegenerative
diseases. Many of the genes discovered over the last decade that are known to affect lifespan belong to evolutionarily conserved biochemical pathways that are also intricately involved in the control of energy metabolism. Diabetes can be considered...
Depression linked to previously unknown dopamine regulator
... previously implicated as a proapoptotic factor in neurodegenerative
diseases such as Alzheimer's disease. These new findings reveal an unexpected role for Par-4 in the dopamine system and present a rare glimpse of molecular mechanisms behind clinical depression. "Current antidepression therapies are mostly based on t...
American Neurological Association 130th Annual Meeting in San Diego
...nalities among Alzheimer's, Parkinson's, and other neurodegenerative
diseases to design treatments. These are some of ...-Alzheimer's, Huntington's, Parkinson's, and other neurodegenerative
diseases present with very different symptoms, but all involve the gradual death of select groups of...
Yale School of Medicine Neuroscientist receives Javits Award
... from amyotrophic lateral sclerosis, the disabling neurodegenerative
disease also known as Lou Gehrig's disease. "The Javits award gives highly productive scientists, whose work is on the cutting edge in their field, an even greater opportunity to understand the interplay involved in the cause and, hopefully, treatme...
Green tea ingredient prevents Alzheimer's-like brain damage in mice
...ains of mice genetically programmed to develop the neurodegenerative
disease process. The component, called epigallocatechin-3-gallate (EGCG), is a major antioxidant in green tea and has been widely studied for its reported protection against certain cancers. Now the USF team provides the first evidence that EGCG dec...
Myelin suppresses plasticity in the mature brain
...uding stroke, head trauma, multiple sclerosis, and neurodegenerative
disease," said senior author Stephen Strittmatter, professor in the Departments of Neurology and Neurobiology. "Recovery of motor function after serious damage to the mature brain is facilitated by structural and synaptic plasticity." Strittmatter's...
Novartis MS drug shows promising results
... Sclerosis MS is the most common inflammatory and neurodegenerative
disorder of the central nervous system, including the brain, spinal cord and optic nerves. MS typically presents itself in relapsing forms. The relapsing-remitting (RRMS) course is the most common form of the disease. Patients suffer acute self-limi...
Mayo Clinic research collaboration discovers why some DNA repair fails
...k of inheriting it. Friedreich's ataxia is another neurodegenerative
disease that may one day have a treatment based in...ereditary non-polyposis colon cancer). "Hereditary neurodegenerative
diseases such as Huntington's disease have no cure and no effective therapy," says Cynthia McMurray,...
Penn researchers discover the powerful tool of simultaneous fMRI and PET imaging
...each other like with stroke, seizure disorders, or neurodegenerative
disorders. That's what led us to this new technique so that we can explore many different aspects of the brain's function." So how does this new simultaneous imaging approach actually work? Radiologists inject a patient with radioactive material used...
Floyd E. Bloom wins 2005 Sarnat Prize in Mental Health
...ons in the brain will lead to new understanding of neurodegenerative
disorders such as Alzheimer's and Parkinson's, Bloom co-founded a biotechnology firm called Neurome Inc. in 2000 that seeks new ways to diagnose and treat these diseases. In addition to his research pursuits, Bloom served five years as editor in ch...
Gas-blockers might slow down Alzheimer's disease
...vastating disease. Alzheimer's disease is a lethal neurodegenerative
disease that causes progressive memory loss and dementia. The disease is associated with a build-up in the brain of abnormal fragments of a resident brain protein called beta-amyloid protein. Researchers have not yet figured out exactly how the fra...
Scientists show how thinking can harm brain cells
...by which brain cells can be damaged during chronic neurodegenerative
diseases. When inflammation occurs in the brain, n...rincipal investigator. A long-standing villain in neurodegenerative
disease has been glutamate, an amino acid that normally acts as a neurotransmitter. Excess glutamate...
RNA splicing occurs in nerve-cell dendrites
...rons may give rise to cognitive dysfunction. "Most neurodegenerative
and psychiatric illnesses exhibit dendrite dysfunction, therefore, the inability to properly generate spliced RNAs in dendrites or proteins may underlie aspects of these disease processes." By revealing the capacity of mRNA splicing in dendrites, th...
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