A possible new phase for rheumatoid arthritis treatment
...ty of Birmingham, U.K., investigated the processes occurring in the joints of patients within 3 months of the onset of clinical symptoms. They assessed a panel of T cell, macrophage and stromal cell related cytokines and chemokines in synovial fluid samples from inflamed joints of these patients with very ear...Charter activation brings space dimension to European emergency exercise
... as seriously burned The EURATECH 2005 exercise is occurring between 10 and 14 April at the town of Portes-ls-Valence in the French department of Drme. Its name is short for 'European Technological Accident '. A large number of different French groups are participating in EURATECH, including the town and pref...The world's leading researchers in clinical immunology to gather for FOCIS 2005
...d have complete access to the educational sessions occurring at the 2005 Annual Meeting. A press room with interview space, computers, modem lines, telephone and fax services will be available upon request. To download a FOCIS 2005 preliminary program and registration materials, visit www.focisnet.org/meetin...Smoking doubles risk of degenerative eye condition
... macular degeneration], which is the most commonly occurring cause of blindness in the United Kingdom, is yet another reason for people to stop smoking and governments to develop public health campaigns against this hazard," conclude the authors....Research urgently needed to treat blood clots in children
...versity of Alberta. "We don't think of blood clots occurring in children, but they do," said Dr. Patricia Massicotte, a professor of pediatrics at the University of Alberta, and one of the study's authors. A review of treatments for pulmonary thromboembolism (PTE) in children, conducted by the University of Al...Alternate view for pathology of AD
...ively late event in the chronology of the disease, occurring decades after oxidative stress, but might also rep...t mammalian brain appears to represent a naturally occurring process associated with neuroprotective mechanisms." In support of this, previous work by Smith's gr...Study sheds light on age-related changes of prion diseases
... believed to be caused by the mutation of normally occurring proteins called prion proteins and are inevitably fatal. In a laboratory study of the mutation that causes GSS in this family the mutant protein was found to assume its normal shape in the cell, but after it was unfolded it failed to return to its no...Age is not a limiting factor in combined therapy for lung cancer
...ygen was significantly more common in the elderly, occurring in 6 percent of elderly patients compared to no patients in the younger age group. Based on their findings, the authors conclude: "fit elderly patients with locally advanced limited stage small cell lung cancer should be encouraged to receive combin...Second consecutive UH win puts national spotlight on pharmacy student
... challenge is designed to reflect changes that are occurring in practice, encouraging further professional development of the student pharmacist. Students competing in the competition are given a prescription and a patient profile from which they are expected to counsel a patient. Typically, patients present...'Fickle' enzyme helps protect, but also can promote heart failure, animal study shows
...n, at least in mice, be treated with its naturally occurring cofactor, BH4, suggesting a possible therapy in the future." The researchers plan further experiments to evaluate the therapeutic effects of BH4 in hypertrophy and how it, together with NOS3, compensates for the damage that leads to heart failure. F...VELCADE for injection receives EU marketing authorisation for second-line use in multiple myeloma
...myeloma worldwide, with over 26,000 of these cases occurring in the EU.(ref 2) Only 30 percent of multiple myeloma patients survive longer than five years.(ref 3) More than 18,000 people in the EU die each year from the disease. (ref 2) Professor Jesus San Miguel, Professor of Medicine at the University Hospit...Officials simulate bioterrorist attack to test APL-developed disease surveillance
...tion and monitoring of an intentional or naturally occurring emerging pathogen; to identify areas for improvement and enhancement within the system architecture; and to identify specific education and training needs of participants. "What we've seen in this exercise is that the public health experts from the ...FDA approves Boostrix a new US vaccine for adolescents against pertussis
...st 40 percent of cases reported to the CDC in 2004 occurring in this age group. Alarmingly, there was a 743 percent increase in reported adolescent pertussis cases in the last decade. Teens, in whom classic signs and symptoms of pertussis are often absent, may go undiagnosed and be the source of infection fo...Routine procedure during childbirth provides no benefits, study review finds
...ical practice. The procedure remains common today, occurring in more than 1 million of the roughly 4.2 million births nationwide each year. Among first-time mothers, 70 percent to 80 percent have an episiotomy, Thorp said. However, studies published as early as 1983 began to question whether routine episiotom...Research suggests molecular approaches to brain tumor treatment
...f receptor for interleukin 13 (IL-13), a naturally occurring protein that regulates the immune system in the body. Normal cells do not have these same receptors. IL-13 is a very attractive target for molecular anti-brain tumor therapies and two clinical trials are currently ongoing. The new study examined t...Discovery of key inflammation mechanism in COPD could lead to new treatments
... shown that low doses of theophylline, a substance occurring in tea leaves which helps relax the bronchial tubes, could help restore HDAC activity, and potentially reverse the resistance to steroids. Professor Barnes adds: "Although this research is at a fundamental level, the discovery that COPD affects HDAC ...Active vaccine prevents mice from developing prion disease
...rrently, an outbreak of chronic wasting disease is occurring in some Western states, and the disease's geograph...same amino acid composition as equivalent proteins occurring naturally in the body. But the prions turn deadly by changing shape. These "misfolded" proteins tend...UK is in the grip of a nationwide mumps epidemic
...w two papers in this week's BMJ. The outbreaks are occurring predominantly in 19-23 year olds, but cases are also occurring in susceptible children, underlining the importance of ensuring that all children and young adults h...Vitamin D, taxotere combination promising for advanced prostate cancer
...eceived docetaxel alone. Calcitriol is a naturally occurring hormone and the biologically active form of vitamin D. "The data strongly suggest that DN-101, given in combination with docetaxel, will provide a substantial survival benefit to prostate cancer patients without adding toxicity," said Tomasz Beer......time in an animal model that ceramide, a naturally occurring substance that prevents the growth of cells, can be administered through the blood stream to target and kill cancer cells. "Ceramide is the substance that accumulates in cancer tissues and helps to kill cancer cells when patients undergo chemotherap...