Impaired gene helps non-small cell lung cancer resist drug
...erapy to restore NPRL2's function makes the tumors once again sensitive to cisplatin," Ji says. The team packaged a molecular NPRL2-producing machine called a plasmid expression vector in a nanoparticle ? a fatty sphere so small it's measured in billionths of a meter. The nanoparticles are injected into...Weight training does not increase strength but may slow progression in OA patients
...ained at a fitness center twice a week and at home once a week; the sessions at the fitness center were gradually decreased until patients were doing all of the workouts at home after the first year. The ST program included upper-body exercises, but was focused on resistance training for the lower-body. T...New treatment for severe malaria
...onglomerate and lodge in the blood vessels is that once in the blood cell the parasite produces proteins that project from the surface of the cell and bind with receptors on other blood cells and on the vessel wall, and thus act like a glue. The challenge facing scientists has been to break these bonds so...Robot wheelchair may give patients more independence
...f the chair facilitate leg exercises. The patient, once lifted and supported by the torso lifts, can walk as the HLPR Chair moves forward at a slow pace. The current maximum speed is 27 inches per second (0.7m/s). NIST engineers plan to design the HLPR to autonomously dock with toilets, provide voice-act...High risk of migraine, depression and chronic pain for IBS sufferers, large study shows
...ho had consulted a doctor because of IBS, at least once between 1996 and 2002. A group of 27,402 people who did not suffer from IBS acted as the comparison group. Cole et al. took into account the many variables and confounding factors that could have skewed their data in their analysis. Cole et al.'s s...FDA approves Vectibix to treat patients with metastatic colorectal cancer
...bix can be conveniently administered intravenously once every two weeks. Vectibix is expected to be commercially available in early-to-mid October and will be priced at approximately 20 percent less than the other anti-EGFr antibody currently on the market. "Vectibix is the first entirely human antibod...Mathematical tools for predicting facial surgery results
...y in closedform, so mathematics enters the picture once again to providenumerical techniques for producing approximate solutions. With the "virtual patient" data as input, one can use the approximatesolutions to generate an individualized model for that particularpatient. The surgeons can then use the m...Study suggests menthol cigarette smokers may have more difficulty quitting smoking
...s vs. 54 percent of non-menthol smokers. However, once the researchers factored in other social and demographic variables, most of this difference was explained by the fact that African Americans were both more likely to smoke menthols and less likely to quit smoking. "Among smokers who tried to quit, m...Dobbs to give plenary keynote at Drug Information Association conference in Philadelphia, Sept. 26
... gross understatement," saidDobbs. "This industry, once a safe haven for investors and a stable and safepl...ed only a fewyears ago. Pharmaceutical stocks that once led the S&P 500 in growth andstability now trail the pack. Between 1989 and 2005 twenty three well-k...Fatty fish protects against cancer
... fatty fish. The group who ate fresh fish at least once a week but for whom follow-up information were unavailable, saw a 40 per cent reduction. "This is the first time that a link between the consumption of fatty fish and renal cancer has been studied," says Professor Alicja Wolk, one of the scientists...MRIs made safe for people with modern defibrillators and pacemakers
...images from inside the body. "We have turned a once exceptional procedure into one that is now a routine at Hopkins," Halperin says. Among other things, the Hopkins group reprograms the devices, fixing them to a specific sequence. This makes the implanted devices "blind" to their external environ...Two-faced protein can stop metastasis or promote it, researchers say
...he beginning of this dangerous process, or stop it once it starts. "Our data show that this one protein, p120 catenin, is a key player in both suppressing invasion and promoting it," says the study's senior author, Panos Anastasiadis, Ph.D., a Mayo Clinic cancer researcher. "This is very exciting, beca...Breathing problems during sleep increase risk of depression
... The participants stayed overnight in a laboratory once every four years, during which time sleep was monitored with a test known as polysomnography and breathing disturbances were recorded. By May 2005, 449 participants had completed one sleep study, 382 completed two, 319 completed three and 258 comple...'Ticking time bomb': Prisons unprepared for flu pandemic, says new SLU research
...s come to prison with some sort of illness. "And once they're incarcerated, they're more likely to get other diseases. It makes correctional facilities into ticking time bombs. Many people crowded together, often suffering from diseases that weaken their immune systems, form a potential breeding ground ...New launch date for Europe's first polar-orbiting weather satellite
...AT), with the latter set to operate the spacecraft once they are in orbit. These new satellites will form the space segment of the EUMETSAT Polar System (EPS) and probe the atmosphere with high accuracy. They will circle the globe from pole to pole at an altitude of about 817 km, collecting high-resolutio...AAFP, ACP and AOA meet with Congress on Medicare reimbursements to physicians
...cent. We are extremely hopeful that Congress will once again recognize how important it is to fix the flawed Medicare payment formula and assure health care to our seniors." "Medicare beneficiaries rely upon their primary care physicians not only for quality health care, but also for access to other pa...New Orleans 'toxic soup' a less serious problem than initially believed
...ere not as devastating in stirring up chemicals as once feared. "The data shows that there is no real need to ban fish consumption, for instance. Levels of some toxic metals are high in parts of New Orleans, but not generally higher than before Hurricane Katrina or in some other urban areas. Hathaway,...New sunscreen ingredient to heal sunburn and help prevent skin cancer
...ummer days, before 10am and after 3pm. "UVA was once thought to have a minor effect on skin damage, but now it is considered to be a major contributor as it penetrates deeper into the skin than UVB. "It is overexposure to UVA that causes the redness and inflammation, or erythema, associated with sun...Keep slapping on that sunscreen
...do you apply sunscreen? If it's anything less than once every 2 hours, you might be better off not using any in the first place. So says Kerry Hanson, a chemist at the University of California at Riverside. She and her colleagues exposed human skin samples grown in the lab to UV radiation while they wer...Overweight in early childhood increases chances for obesity at age 12
...s found that children who were overweight at least once from ages 2 to 4 were 5 times more likely to be o...rough 11. For example, a child who was overweight once during the elementary school years was 25 times more likely to be overweight at age 12 than was a ch...