Injectable drug, combined with counseling, shows promise in treating alcohol dependence
...dependence. It belongs to a class of drugs called opioid antagonists, for treating alcohol dependence. Although many clinical trials have shown that oral naltrexone can be effective in treating alcohol dependence, its use in clinical practice has been limited, in part because the drug was given as a pill ...Once-a-month naltrexone successfully used to treat alcohol dependence
...ear. Naltrexone belongs to a class of drugs called opioid antagonists. Although many clinical trials have shown that oral naltrexone can be effective in treating alcohol dependence, its use in clinical practice has been limited, in part patients have to take the pill daily. In this trial conducted at 24 sit...Narcotic drugs effective for severe, chronic pain in older patients
...er patients' desires/needs to escalate the dose of opioid pain medications they take -- a class of drugs inc...tient requests for ever-increasing doses. Extended opioid use at high doses can alter immune and hormonal function and, ironically, increase pain sensitivity....Brain's own marijuana-like chemicals play key role with stress-induced pain relief
...G response intest rats, they could only detect the opioid form of stress-inductedanalgesia in response to pain stimuli. Further, when rats used in study were given a small molecule inhibitordeveloped by Piomelli and his collaborators, stress-induced analgesiaincreased dramatically, proving the connection be...New drug abuse treatment shows promise
Patients who receive buprenorphine treatment for opioid addiction in an officebased setting are more likel...s who are unable or unwilling to use methadone for opioid addiction." Demographic information and the individual's history of drug abuse were compiled from 19...Chronic arthritis pain and the disappointment of u-opioid therapy
... highlight a possible inadequacy of the endogenous opioid system to alleviate chronic arthritis pain," notes study author Dr. Jason McDougall. By offering clear insights into the disappointment of u-opioid therapy, this study suggests the need for rethinking the best use of endomorphin 1 and redirecting pa...Medication appears effective in treating teen heroin addiction
... treatment interventions for adolescent heroin and opioid abusers. Lisa A. Marsch, Ph.D., and colleagues at the University of Vermont, Burlington, evaluated the relative efficacy of buprenorphine hydrochloride and another drug, clonidine hydrochloride, in detoxification of opioid-dependent teenagers. (Dr...Pharmacies in minority, low-income areas less likely to carry sufficient pain medications
...pronounced gap in the availability of prescription opioid analgesic medications. The study, which appears in...likely to have sufficient supplies of prescription opioid analgesic medications drugs that include oxycodone, morphine and methadone when compared with pred...A recipe for overeating: Studies outline dangers of mixing stress, deprivation and tempting foods
...gham focused on the regulatory role of the brain's opioid system. Opioids or endorphins (the brain's "feel ...eating rats responded to drugs that either turn on opioid receptors (butorphanol, which treats pain) or block them (naloxone, which treats heroin addiction). ...Fentanyl patch safe and effective alternative to oral opioids for pediatric pain patients
...tudy says using a transdermal patch to deliver the opioid fentanyl is an effective way to control pain in ch...ad a history of chronic severe pain and prior oral opioid use. They were transitioned to the fentanyl patch adjusted to equal the concentration of previous or...New pain research: Routine Tylenol for nursing home residents with dementia increases activity
...oes not carry the side-effect risks of more potent opioid analgesics. Under certain circumstances, prophylactic treatment of pain in elderly persons with dementia therefore appears safe and effective in increasing active engagement with the environment."...Studies confirm effectiveness of fentanyl lozenges for 'breakthrough' cancer pain
...ain and relief was compared with morphine or other opioid rescue medication, or placebo. The review appears in the most recent issue of The Cochrane Library, a publication of The Cochrane Collaboration, an international organization that evaluates medical research. Systematic reviews draw evidence-based con...Antipsychotic drug may block addiction, UIC researchers find
...sychotic drug can stop the addictive properties of opioid painkillers in mice. The researchers injected a s...mportant role in the generation and maintenance of opioid tolerance," he said. Tolerance is a hallmark of drug dependence. "Trifluoperazine targets this path...Morphine and topical anesthesia found effective in treating pain in newborn infants
...ical local anesthesia (tetracaine) and intravenous opioid analgesia (morphine), used alone or in combination...atheter placement, but similar in effectiveness to opioid analgesia alone. Local anesthesia alone, however, was not consistently different from no analgesia, ...Morphine and topical anaesthesia effective in treating procedural pain in newborn infants
...a topical anaesthesia (tetracaine) and intravenous opioid analgesia (morphine), used alone or in combination, for management of pain in newborns undergoing insertion of a central venous catheter. Many hospitalized newborns require central lines for the administration of medication and nutrition. The randomi...March/April 2006 Annals of Family Medicine Tip Sheet
...FAMILY PHYSICIAN'S PERSPECTIVE With the crisis of opioid addiction in the United States growing at a rapid ...e of buprenorphine, the office-based treatment for opioid dependence. The author acknowledges that this problem is no longer limited to inner-city neighborho...Late-breaking Digestive Disease Week news
...o rapidly block the effect of these medications on opioid receptors outside the central nervous system. Since methylnaltrexone does not cross the blood-brain barrier, it does not interfere with brain-centered pain relief. Study Design In the double blind, placebo-controlled trial, 133 patients with advan...ASCO and ESMO announce Consensus Statement on Quality Cancer Care
...ve access to pain management, including the use of opioid analgesics, and other supportive care options....Transporter is possible target for safer pain medicine
...llege of Georgia. Studies have shown, for example, opioid peptide levels increase during childbirth. Many po...natural pain control system by directly activating opioid peptide receptors. While pain control is effective, it comes at a price: potential addiction, immune...Studies find that 'broken heart syndrome' can result from opioid withdrawal, cocaine use
...rst report of broken heart syndrome resulting from opioid withdrawal in an adult. Opioids such as OxyContin are becoming increasingly common for pain management, the report's authors say. Given the drug's prevalence, physicians should proceed with caution when removing patients from high-dose opioids in ord...