Notch signaling molecule important in type 2 immunity
(Philadelphia, PA) - Defects in immune system cells called T helper cells may lead to diseases characterized by a faulty inflammatory response such as autoimmunity and asthma. Understanding the molecular steps involved in how T helper cells mature may help researchers develop treatments for these diseases.... ...Helper T cells differentiate into two different types of cells Th1 or Th2 which are...Study finds unexpected results in acid suppression between two OTC heartburn treatments
... Researchers also report evidence...New study shows risk of serious GI problems & bleeding intensified by common OTC pain medications
HONOLULU, October 31, 2005 -- Patients who combine the common over-the counter pain medications ibuprofen and naproxen with aspirin have a risk of gastrointestinal complications including ulcers, perforations and bleeding that is two to three times greater than patients who take these medications but do not combine them with aspirin. Findings of a large retrospective review of medical records fo...The economics of prescription drugs versus OTC
Governments in several countries with public Pharmacare and in a few provinces in Canada are considering reclassifying some drugs from prescription to over-the-counter status. In a CMAJ essay, Lynd and colleagues comment on the economic effects of such changes. ... ...The drugs being considered are used in a wide variety of chronic diseases. They include proton pump inhibitors, beta-blockers, diu...Notch protein signaling directs early T-cell development
(Philadelphia, PA) Researchers at the University of Pennsylvania School of Medicine have recently clarified the role of the Notch protein in T-cell development. T cells are required for many aspects of immunity, including fighting viral infections, providing cancer surveillance, and regulating multiple aspects of the immune response. ...... T cells are made in the thymus, a small organ situated...OTC treatments for reflux fail to match relief of prescriptions
CHICAGO, IL (May 16, 2005) New research presented today at Digestive Disease Week 2005 (DDW) suggests that over-the-counter treatments for gastroesophageal reflux (GERD) symptoms may not be as effective as treatment options prescribed by a physician. DDW is the largest international gathering of physicians, researchers and academics in the fields of gastroenterology, hepatology, endoscopy and g...