Migraine treatment and prevention in women
...rmined that the benefits of the preventive therapy outweigh the risks to both mother and fetus, medications such as propranolol hydrochloride, verapamil hydrochloride and topiramate may be used. However, valproic acid, divalproex sodium and ergot derivatives should never be prescribed to pregnant patients. ...Estrogen plus testosterone therapy may increase risk of breast cancer in postmenopausal women
...ne health, the increased risk of breast cancer may outweigh these benefits."(Arch Intern Med. 2006;166:1483-1489. Available pre-embargo to the media at www.jamamedia.org .) ...Media availability: Drug found to help scleroderma patients
... conclude that the benefits of treatment appear to outweigh the risks. "Cyclophosphamide versus Placebo in Scleroderma Lung Disease," by Donald P. Tashkin, M.D., of the University of California at Los Angeles Medical Center and others, will be published in the June 22 issue of the New England Journal of Medic...Study compares treatment options for patients with brain metastases
...ent survival, the control of systemic cancer might outweigh the frequent recurrence of brain tumors. Therefore, SRS alone could be a treatment option, provided that frequent monitoring of brain tumor status is conducted," the authors write....Study finds ways to improve detection of blood clots in the lung
...volve some exposure to radiation, but the benefits outweigh the risks. Risk factors for pulmonary embolism include blood clots in the leg or a history of such problems, and certain inherited conditions that increase the risk for blood clotting. Individuals who recently have been treated for cancer, have been...For patients with severe lung injury, less is more
...ut whether increased risks for other complications outweigh the benefits of the device. In FACTT, PAC-guided therapy did not improve survival or organ function compared to CVC. After 28 days in the study, the numbers of ventilator-free days and ICU-free days also were similar between the two groups. However,...Millions squandered in unnecessary tests ordered in routine doctor visits
...those which the panel recommended against as risks outweigh the benefits. These "C" and "D" procedures fell into two categories: "interventions"--this includes an electrocardiogram (EKG) that records heart activity and X-rays − and procedures that are analyzed in a laboratory: a urinalysis; a hematocri...Rheumatoid arthritis drug linked to serious infections and cancers
...nfections, it does not mean that overall the risks outweigh the benefits for patients," he says. "The short duration of trials included in our analysis does not allow any conclusions about the long-term risks of TNF-blocking antibody treatment in rheumatoid arthritis. It may turn out that the sustained benefi...Doctors widely prescribe drugs without adequate scrutiny, Stanford scientist finds
...ditions, the potential benefits of treatment might outweigh the increased risk associated with off-label use. A physician might choose to prescribe a drug off-label to adjust for a patient's sensitivities, to avoid interactions with other drugs or to try a different approach if FDA-approved drugs haven't work...Online calculator and chemotherapy order systems reduce medication errors in children
...ible orders and adherence to safety procedures all outweigh the negative effects, researchers say. Because pediatric chemotherapy is such a complex process, it was crucial for researchers to know exactly where mistakes were most likely to occur before they designed the program. To do so, Lehmann and colleague...New guidelines offer power to prevent stroke
...hose risk is sufficiently high for the benefits to outweigh the risks associated with long-term aspirin use. The evidence is not strong enough to recommend aspirin in men at high risk of stroke. Men at high cardiovascular risk can also benefit from treatment with aspirin for primary prevention, Goldstein sa...Should we screen people for depression?
...or example, that the benefit from screening should outweigh the harm and that the screening programme should be cost effective. Opportunistic screening and population level screening for depression do not fulfil the criteria of the National Screening Committee, say the authors. However, the assumption has bee...Steroids do not prolong survival in intensive care patients with ARDS on life support
...erate doses of steroids seen in some ARDS patients outweigh the risks of neuromuscular complications is an issue that physicians, patients, and the patients' families will need to grapple with," said Gordon Bernard, MD, director of the Division of Allergy, Pulmonary and Critical Care Medicine at Vanderbilt Un...Studies evaluate health effects of dental amalgam in children
...r the potential risks of dental amalgam in any way outweigh its benefits, and we needed to make the determination first in children, who may be more sensitive to any adverse effects of mercury," said Tabak. The two studies, whose results are reported this week in JAMA, are: the New England study, which was...No link between estrogen-only therapy, breast cancer in postmenopausal women
...hat the risks of taking estrogen did not appear to outweigh the benefits, which included relief from menopausal symptoms, stronger bones and the suggestion of a decreased risk of breast cancer. Stefanick said she understood why officials at the National Institutes of Health halted the estrogen-only trial, tho...Soy intake associated with reduced risk of breast cancer
...ods in the diet, modest though they may be, likely outweigh any risks for the population as a whole, the authors said....Soy foods associated with small reduction in risk of breast cancer
...ods in the diet, modest though they may be, likely outweigh any risks for the population as a whole, the authors said....Prostate treatment decisions based on perception more than fact
...f treatment efficacy related to cancer control far outweigh available supporting evidence, and most patients appear to select a prostate cancer treatment primarily based on its perceived ability to control the tumor," conclude the authors....Older men with early prostate cancer survived longer with treatment vs. observation
... lives and whether the benefits of early detection outweigh the risks of complications from follow up diagnostic tests and cancer treatments. The cases examined in this study were diagnosed between 1991 and 1999. The men ranged from 65 to 80 years old at diagnosis. Median age at diagnosis was 72. A total o...Anabolic steroid use increases heart attack risk and causes liver damage
...s of immediate weight gain could still potentially outweigh the risks of longer-term heart and liver damage. For these patients, he says, it is important to have a store of fat as well as muscle mass, because "opportunistic infections burn up muscle if there's no fat there. The more fat you have, the less mus...