Autistic children's abnormal metabolic profile findings
...olic profile indicating increased vulnerability to oxidative stress. The scientists also identified a signific...ren, indicating presence of a significant level of oxidative stress. Oxidative stress occurs when the antioxidant system fails to counteract the generation or e...Hemodialysis causes antioxidant loss leading to long-term complications
...n Hemodialysis International discusses the role of oxidative stress (OS) in dialysis patients, an imbalance whi...ced by the dialysis process which further enhances oxidative stress. This state is strongly associated with long-term complications such as cardiovascular disea...News tips from the Journal of Neuroscience
...to cellular stress caused by protein misfolding or oxidative damage. For example, mutant or overexpressed a synuclein causes intracellular inclusions (Lewy bodies) and cell degeneration of dopamine neurons. Such mechanisms are considered central to the pathogenesis of Parkinson's disease. This week, Cao et al....Alternate view for pathology of AD
...chronology of the disease, occurring decades after oxidative stress, but might also represent a response aimed at reducing oxidative damage." There is growing evidence that oxidative stress is a significant factor in the development...Scientist works to reduce side effects of radiation therapy
...s believe the cause may be chronic inflammation or oxidative stress, which occurs when cells cannot remove free radicals, or structurally unstable cells that can damage healthy cells. Robbins' project is based on new evidence that some of the same drugs used to treat obesity and diabetes may also prevent infl...'Fickle' enzyme helps protect, but also can promote heart failure, animal study shows
...ad, the enzyme produces factors that contribute to oxidative stress in the heart. When the researchers restore...rrying blood from the heart to create pressure and oxidative stress. Hearts of untreated mice with NOS3 doubled in size after three weeks and almost tripled in ...Study shows grapefruit extract can heal stomach ulcers
...uit and the ability of this fruit extract to limit oxidative stress in the ulcerative gastric mucosa have therapeutic properties that, when combined with additional therapies, can be especially beneficial for healing of gastric ulcers." Alcohol-Induced Changes in Gut Permeability and Liver Injury are Influenc...Newly discovered 'branding' process helps immune system cells pick their fights
...cause T cells to attack the beta cells." Damaging oxidative reactions are also believed to play a role in atherosclerosis. Scientists suspect oxidative damage in the blood vessel walls may lead to immune reactivity that contributes to narrowing and sti...Red delicious, Northern Spy apples have most antioxidants, chemists find
... in apples appears to protect brain cells against oxidative stress, a tissuedamaging process associated with Alzheimers and other neurodegenerative disorders. This study was published in the December 1, 2004, issue of the Journal of Agriculture and Food Chemistry. Heart disease. Antioxidants found in ap...Bad metabolism in blood vessels linked to high blood pressure and atherosclerosis
...lux of oxygen through the blood vessel wall caused oxidative damage, high blood pressure and atherosclerosis." ...according to Semenkovich. He says it's likely that oxidative damage accumulates in cells, and the mitochondria eventually become defective. As cells try to compe...Prevent prostate cancer with antioxidants? Gene pathway may reveal more clues
...lly, cells with functioning Nkx3.1 seem to process oxidative free radicals appropriately," says Theodore L. DeW... "But cells with faulty Nkx3.1 genes cannot manage oxidative injury. Then, their DNA gets damaged, and that leads to other mutations that in turn can bring abou...New nutritional challenges emerge for HIV care providers
...e progression for many patients, may also increase oxidative stress. "Oxidative stress" refers to the state of imbalance that exists when chemically unstable by-products of metabolism exceed the body's capacity to quench them, either with its own natural antioxidants or with those obtained from the diet. The p...Mechanism controlling DNA damage response has potential novel medical applications
...mal tissues from dying after exposure to toxins or oxidative damage," he added. Kastan is senior author of the Cell paper. The discovery of the roles of RPL26 and nucleolin in p53 production may have much broader implications than just the regulation of p53 levels in response to DNA damage, according to Kast...Flavonoids may inhibit prostate cancer
..."Apigenin has been shown to lower inflammation and oxidative stress, and exerts growth inhibitory effects on cancer cells." In the study, Gupta and his team orally fed apigenin to mice two weeks before implanting a prostate tumor, then continuing the feedings for eight weeks. In a second protocol, apigenin was...Phenolic compounds may explain Mediterranean diet benefits
...ink, looking at our results, that the reduction in oxidative stress and the increase in the nitric oxide bioavailability are behind the observed improvement in ischemic reactive hyperemia," Dr. Prez Jimnez said. Dr. Prez Jimnez said that olive oil may be superior to seed oils because it is a natural juice, pre...The role of Type II Collagen in rheumatoid arthritis
...xcess oxygen. In addition to unleashing MMPs, the oxidative stress provokes non-enzymatic glycation a chemica... author, Ahuva Nissim, Ph.D. "We propose that the oxidative modification of CII creates a CII autoantigen." This hypothesis has important implications for the ...Researchers discover new way to stimulate brain to release antioxidants
...in nerve cells to release antioxidants and counter oxidative stress," said Stuart Lipton, M.D., Ph.D., Director...in nerve cells that is designed to protect against oxidative and nitrosative stress (which produces free radicals) and excitotoxicity. This pathway, known as Ke...Cocoa intake linked to lower blood pressure, reduced risk of death
...lso be related to other disease that are linked to oxidative stress (e.g. pulmonary diseases, including chronic obstructive pulmonary disease, and certain types of cancer) ," the authors conclude. "However, this merits further investigation."...Major biomarker candidates for Alzheimer's disease explored
...tau. Other biomarkers that target inflammatory and oxidative damage processes may have future potential.In a di...niversity), in "Quantitative in vivo biomarkers of oxidative damage and their application to the diagnosis and management of Alzheimer's disease," discuss how th...Hypertension drug may restore cardiovascular function in African Americans
... and can restore levels of nitric oxide and reduce oxidative stress. A deficiency in nitric oxide and high oxidative stress can cause a variety of health problems, including heart attacks, stroke and heart failure, as...