Tag: "parasites" at medical news

Anti-malaria drug combination could help address treatment crisis in Africa

...r the start of treatment. Failure to clear malaria parasites from the blood was found in 42% of patients on amodiaquine, 20% on amodiaquine and sulfadoxine-pyrimethamine, 11% on amodiaquine-artesunate, and 1% on artemether-lumefantrine. Recruitment to the amodiaquine group was stopped early because of the high...

Reducing malarial transmission in Africa

...t might reduce selective transmission of resistant parasites in treated patients....

NIAID scientists unveil mechanism behind resistance to severe malaria

...w hemoglobin type C impairs the ability of malaria parasites to cause disease symptoms. "This research gives ...alled PfEMP-1. To evade the immune system, malaria parasites produce proteins, including PfEMP-1, that remodel the red blood cell's surface to their advantage. F...

Parasite genome sequences offer hope for new drugs and vaccines, Science studies say

...sequenced and compared the genomes of three of the parasites responsible for sleeping sickness, Chagas disease ...evastating diseases of the developing world. These parasites collectively cause disease and death in millions of humans each year, and the new genome sequences p...

Three deadly parasite genomes sequenced

...e globe have determined genetic blueprints for the parasites that cause three deadly insect-borne diseases: Afr.... At a genetic level, the similarities among these parasites outweigh their differences. The shared genes give scientists a vastly expanded array of targets for ...

Not enough is known about treating malaria in pregnancy, researchers say

...y better than the drug quinine at clearing malaria parasites from the bloodstream and reducing fever in pregnant women. The risk of treatment failure was 9 percent less in the group receiving the combination drug regime, compared to treatment failure rates in the quinine group, the researchers found. The stud...

Wet combing four times more effective than chemical treatments for head lice

...h published online by the BMJ today. Head lice are parasites that usually infest the scalps of school age children. Current treatments include over the counter insecticide products or fine tooth combing of wet hair using a specially developed "Bug Buster" kit. However, chemical resistance is a problem, while w...

Researchers discover how malaria parasite disperses from red blood cells

...ained the blood cells green, the other stained the parasites red. In the first stage of the merozoites' release...ood cell resembles a lop-sided fried egg, with the parasites visible as a sphere near the center of the cell. (A diagram of the entire sequence appears at http...

KwaZulu-Natal's successful fight against malaria

...been particularly resurgent in recent years as the parasites transmitting the disease have developed resistance to many of the existing drugs. Approximately a million people are killed by malaria every year, predominantly in Africa. KwaZulu-Natal was the first Ministry of Health in Africa to introduce an artem...

Institute for OneWorld Health receives multimillion dollar grant

...transmitted by sand flies, which spread leishmania parasites that attack internal organs. VL is endemic in 62 countries, and the number of new VL cases per year is estimated at 500,000. With the exception of malaria, VL kills more people than any other parasitic disease. OneWorld Health completed phase III ...

Older drugs may be good stopgap treatment for malaria in Africa

...han the other drug combination at clearing malaria parasites from the blood at a particularly infectious stage ...ination to reduce the number of infectious malaria parasites in the blood to clinically insignificant levels. Reducing the parasite load is important because it ...

Elephantiasis close to elimination in Egypt

...g administration are likely to have eliminated the parasites that cause elephantiasis in most areas of Egypt, according to a study in this week's issue of The Lancet. Elephantiasis, or lymphatic filariasis, is a disfiguring and disabling tropical disease caused by infection with parasitic worms. Egypt is one o...

Global program to eliminate elephantiasis has early success in Egypt

...rms are nematodes closely related to the heartworm parasites that infect dogs and cats. Infections with the worms, which are spread by mosquitoes, can lead to lymphatic filariasis, a condition where the worms lodge in lymphatic vessels. This triggers inflammation that blocks the drainage normally provided by t...

A Jekyll and Hyde of cytokines: IL-25 both promotes and limits inflammatory diseases

...e infected with Trichuris, a species of intestinal parasites known as whipworms, the researchers were able to d... helper cells that fight infection with intestinal parasites like Trichuris, " said Colby Zaph, a co-author and Irvington Research Fellow at Penn. "In industria...

The World Bank accused of deception and medical malpractice in malaria treatment

...drug-treatment policies to match different malaria parasites within different regions of the country. They write that this approach is more effective than a one-size-fits-all policy in a large country like India where patterns of drug sensitivity vary within the country itself. Sarbib and colleagues present ev...

Immune culprit in malaria-associated anemia

... the major causes of death among children. Malaria parasites use RBCs as multiplication factories, rupturing the cells as progeny parasites exit. Infection also hampers the production of new RBCs from the bone marrow, an effect this group r...

OHSU researchers discover possible HIV therapy in an animal study

... infections caused by bacteria, viruses, fungi and parasites that are normally held at bay by a healthy human body. The infected body's inability to fight off these "intruders," leads to death. "To learn more about HIV, its impacts and possible treatments, we study simian immunodeficiency virus (SIV), a close...

Reports characterize fungal eye infections among soft contact lens wearers

...m or other fungal species in addition to bacteria, parasites or viruses as causative organisms," the authors conclude. "Clinicians should conduct the necessary clinical and laboratory investigations to establish a specific diagnosis promptly to initiate the most specific, efficacious therapy." (Arch Ophthalmo...

Increase in counterfeit antimalarial drugs prompts call for crackdown, better detection

...ate tablets, the authors note. Exposure of malaria parasites to low concentrations of artesunate in patients ta...e the risk for the selection and spread of malaria parasites that are resistant to artemisinin derivatives. That could lead to a loss of effectiveness for these ...

Wild vs. lab rodent comparison supports hygiene hypothesis

...hile the IgE type is likely a key defender against parasites and has been implicated in allergic reactions in h..., since wild rodents would likely have encountered parasites that activated the production of antibodies as protection. However, the production of polyreactive, ...

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