Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinson's symptoms
... ... Results of the study by Emory scientists, along with the University o...Investigating the causes of Parkinson's disease
... ... Dr Bedford will be using a new genetic model of Parkinsons to further understanding of how and why nerve cells die. Her research will also take a clos...Risk of Parkinson's disease increases with pesticide exposure and head trauma
... ... The two risk factors are potentially modifiable, the authors say. Head trauma resulting from contact sports such as boxing can be avoided and further research could identify more specifically which pesticides are associated with this effect, so that the...Implanting dopamine generators in brain cells obtains improvement in Parkinson's in monkeys
... , and have corroborated the conclusions of a previous study, published in 1...Exercise may lead to improvement in patients with Parkinson's
... ... Recent studies have shown that exercise can have beneficial effects in patients with Parkinson's Disease but the underlying reasons haven't been fully e...Coenzyme Q10 does not improve Parkinson's disease symptoms
... Parkinson's disease is a neurodegenerative disorder characterized by tremors and difficulty with walking or other movements. The biological mechanisms underlying the condition are not fully understood, but researchers suspect a malfu...Alzheimer's, Parkinson's, type 2 diabetes similar at molecular level
... ... The researchers s...New blood test can diagnose and monitor treatment of Parkinson's disease
... Dr Qiao-Xin Li and colleagues from The University of Melbourne and The Mental Health Research Institute of Victoria, along with Prof Malcolm Horne from the Howard Florey Institute, found people with PD had low levels of the brain-secreted protein alpha-synuclein in their bloo...Drugs for Parkinson's disease may ease stroke-related disability
... ... Like stroke patients with motor neglect, Parkinson's patients are also slow to initiate responses involving movement. Scientists attribute this deficit in Parkinson...Energy supplement under study for Parkinson's disease
... ... We think it may help cells that are damaged or overworked, says Dr. Sethi, a site principal investigato...Worldwide Parkinson's cases will double in next 25 years
... In recent years, a great deal of resources and energy have been focused on confronting infectious diseases such as HIV, malaria, and tuberculosis. This is highlighted by high-profile priv...Drug improves tremors, involuntary movements in Parkinson patients
... The three-month, multi-center study in Japan involved 279 Parkinson disease patients who weren't responding well to the commonly used drug, levodopa, to manage their symptoms. The patients were divided into groups that took 25, 50 or 100 mg a day of...Synchronous neuronal firing may underlie Parkinson's disease
... ... "Imagine an orchestra playing a beautiful symphony...Dopamine imbalances cause sleep disorders in animal models of Parkinson's disease and schizophrenia
... ... The same processes likely occur in humans, according to the researchers. They said the findings give insight into the sle...Appetite changes, depression signal impulse control disorders in Parkinson disease
... Compulsive gambling, hypersexuality, and excessive shopping have been linked to treatment with dopamine agonists in small numbers of patients....Large collaborative effort provides first publicly available genetic data for Parkinson's research
... PD is a chronic neurodegenerative disease that occurs in more than one per thousand people. Risk for PD is increased by 70% in individuals who have a sibling with the disease, which suggests that there could be an underlying genetic cause. However, traditional testing of potential genetic associations in idiopathic (without an id...Laser probe of a brain pigment's anatomy may offer insight into Parkinson's disease
... Other scientists previously had determined via chemical analysis that the dark pigment, called neuromelanin, is composed of the two pigments: eumelanin, found in black-haired people, and pheomelanin, found in redheads. But how those pigments are arranged structurally remained unknown -- a...Pesticide exposure could increase risk of early onset of Parkinson's disease
... The concept of an accelerated disease process is a new twist in the investigation of the long-suspected lin...Two copies of G2019S Parkinson's gene mutation doesn't lead to more severe disease
... In most diseases with a genetic cause or component, two copies of a bad gene lead to more severe visible manifestation of the disease. Researchers expected to see worse symptoms, the disease start earlier in life and a shorter life span for those with two copies of the LRRK2 ge...Early warning test for Parkinson's receives national recognition
... This national publication will be launched by The Minister for Health and Ageing, Tony Abbott at 10am,...Friday 1 September in the Scientia Gallery, University of New South Wales. ... Dr Double's research into Parkinson's disease looks at the function of neuromelanin, a pigment unique to human brains. In the brain cells of a person with Parkinson's di...University of Pittsburgh named Parkinson Disease Center for Advanced Research
... J. Timothy Greenamyre, M.D., Ph.D., UPMC Endowed Professor of Neurology and chief, movement disorders division, University of Pittsburgh School of Medicine, will direct all aspects of the center and chair the center's executive committee. Dr. Greenamyre, an internationally renowned Parkinson's disease researcher,...Strong evidence of a genetic risk factor for Parkinson's disease
ROCHESTER, Minn. -- A Mayo Clinic-led international research collaboration -- one of the largest studies of its kind -- provides strong evidence that a genetic risk factor may account for ...3 percent of the cause of Parkinson's disease. ... ... "This is an important step forward because the contribution of common genetic risk factors to the development of Parkinson's has long been suspected,...Nicotine found to protect against Parkinson's-like brain damage
New research suggests that nicotine treatment protects against the same type of brain damage that occurs in Parkinson's disease. The research was conducted in laboratory animals treated with MPTP, an agent that produces a gradual loss of brain function characteristic of Parkinson's. Experimental animals receiving chronic administration of nicotine over a period of six months had 25 percent less d...Mayo Clinic links allergies to Parkinson's disease
... ... Previous studies had shown that people who regularly take nonsteroidal anti-inflammatory d...New genetic model for Parkinson's disease
Researchers at the Karolinska Institute in Sweden are homing in on mechanisms that may explain one set of causes for Parkinson's disease. In mice they have mimicked disturbances of mitochondria thought to be one cause of disease. By genetic means the disturbance of mitochondria - the energy factories of cells - were directed to those nerve cells that produce the transmitter substance dopamine and...Neurologists with expertise in brain stimulation therapy help Parkinson's patients
... Deep brain stimulation is a surgical procedure that involves implanting electrodes into the brain to electronically stimulate areas that control movement, treating Parkinson's disease symptoms s...Pesticide exposure associated with incidence of Parkinson's disease
A prospective study of over 143,000 people found that those who reported exposure to pesticides had a 70 percent higher incidence of Parkinson's disease. Exposure to other occupational hazards, including asbestos, chemicals, acids, solvents, and coal or stone dust did not lead to an increased disease risk. The study is published in the July issue of Annals of Neurology, a journal published by Joh...Pesticides exposure associated with Parkinson's disease
Boston, MA -- In the first large-scale, prospective study to examine possible links between chronic, low-dose exposure to pesticides and Parkinson's disease (PD), researchers at the Harvard School of Public Health (HSPH) have shown that individuals reporting exposure to pesticides had a 70 percent higher incidence of PD than those not reporting exposure. No increased risk of PD was found from rep...Study concludes that pesticide use increases risk of Parkinson's in men
ROCHESTER, Minn.--Mayo Clinic researchers have found that using pesticides for farming or other purposes increases the risk of developing Parkinson's disease for men. Pesticide exposure did not increase the risk of Parkinson's in women, and no other household or industrial chemicals were significantly linked to the disease in either men or women. ...... Findings will be published in the June issu...Damage from oxygen may be one cause of Parkinson's disease
Charlottesville, Va. Research by neuroscientists at the University of Virginia Health System shows that oxygen free radicals are damaging proteins in mitochondria, the tiny cellular 'batteries' of brain cells. This damage may be one main cause of Parkinson's Disease (PD), the chronic movement disorder that affects at least one million Americans. UVa scientists believe the damage is taking plac...JRRD tipsheet: Focus on stroke, Parkinson's treatment, wheelchair durability
, pg. 717... Intense, short-term, upper-limb robotic therapy improved motor outcomes among chronic stroke patients. Investigators enrolled 30 patients with upper-limb impairment due to stroke. Over 3 weeks, 18 sessions of robot-assisted therapy were delivered with the use of a robotic exercise device. Significant improvements were observed for severely impaired participants, which indicates that...Agent protects Parkinson's neurons from rotenone toxicity
BUFFALO, N.Y. -- Researchers at the University at Buffalo affiliated with the New York State Center of Excellence in Bioinformatics and Life Sciences have identified a novel agent that can protect neurons involved in Parkinson's disease from being destroyed by the pesticide rotenone. ... The agent, called L-AP4, activates a critical group of receptors called group III metabotropic glutamate rec...Variants in three estrogen-related genes linked to Parkinson's disease in women
ROCHESTER, Minn. -- Mayo Clinic researchers have discovered a possible connection between increased risk for Parkinson's disease and variants in three genes that control estrogen production and activity in the body....... The findings will be presented Tuesday at the American Academy of Neurology meeting in San Diego. ...... "We and other investigators have found evidence that estrogen helps pr...Genetic perversity: Smoking & gene avert Parkinson's
It has long been known that smoking offers some protection against developing Parkinson's disease and now a Queensland University of Technology PhD researcher has found out part of the reason why....... Yifu Deng of QUT's School of Public Health studied the interplay between genetics, smoking and the development of Parkinson's disease with 400 people who had Parkinson's disease and 400 people wit...Risk takers may have lower rates of Parkinson's disease
Risk takers may have lower rates of Parkinson's disease, suggests research in the Journal of Neurology Neurosurgery and Psychiatry....... Parkinson's disease is a degenerative neurological disorder, which becomes more common with older age. But its cause is still unclear....... The research team compared 106 patients with confirmed Parkinson's disease with 106 healthy people of the same age and s...Gene therapy 'turns off' mutation linked to Parkinson's disease
A group of Northwestern University researchers is developing a novel gene therapy aimed at selectively turning off one of the genes involved in the development of Parkinson's disease. ... The gene therapy, described in the January online issue of the journal Experimental Neurology, was designed by Martha Bohn and her laboratory group at Northwestern University Feinberg School of Medicine. ... B...Motor symptoms associated with increased risk for future Parkinson's disease
Elderly people who complain of stiffness, loss of balance and tremors may be at increased risk for future Parkinson's disease (PD), according to a study posted online today that will appear in the April 2006 print issue of Archives of Neurology, one of the JAMA/Archives journals....... PD develops over time as neurons in certain areas of the brain that control muscle movement slowly waste away, a...Scientists close in on genes responsible for Parkinson's disease
Scientists have identified 570 genes that act abnormally during the development of Parkinson's Disease, a finding which could help doctors predict the likelihood of it developing, and provide targets for new treatments....... The research published in Neurogenetics, by the team from Imperial College London and the University of Liege, Belgium, uses microarrays to analyse brains from Parkinson's p...Evidence links cocaine abuse and Parkinson's disease
Adults who abuse cocaine might increase their risk of developing Parkinson's disease (PD), and pregnant women who abuse cocaine could increase the risk of their children developing PD later in life, according to results of laboratory studies performed by investigators at St. Jude Children's Research Hospital. ...... The study's findings are important because there are currently more than 2 millio...Eye cell implants improve motor symptoms for Parkinson patients
CHICAGO A preliminary study suggests that implants of cells from the human retina improved motor symptoms in patients with Parkinson disease, and they appear to be safe and well tolerated, according to a report in the December issue of Archives of Neurology, one of the JAMA/Archives journals.... ...Parkinson disease (PD) is a neurodegenerative disorder characterized by tremor, rigidity, postural...