Study finds HIV protease inhibitor drugs may adversely affect the scaffolding of the cell nucleus
... and cause a host of disease phenotypes, including partial loss of body fat depots and metabolic syndrome. The fact that HIV protease inhibitors block ZMPSTE24 and have been associated with side effects similar to those observed with a genetic deficiency in ZMPSTE24 is intriguing, said Loren Fong, Ph.D., s...Chemical in brain acts like a fuel gauge
...at the University of Southern California provide a partial answer in the July 4 issue of The Journal of Neuroscience. Their study, highlighted by the journal on its news page, identifies a chemical that sends a low blood sugar message to a part of the brain that can do something about it. The neurotransm...Early-morning Friday classes may prevent students from getting sloppy on 'thirsty Thursdays'
...es in return for additional instructional support, partial release from other academic service obligations, or even salary considerations." In summary, said Wood, university administrators should seriously consider increasing the number of Friday classes, either overall, or specifically for individuals who...Parents of chronically ill kids are helped by better access to federal and employer leave
...tatewide payroll tax to provide up to six weeks of partial pay for employees to care for ill family members. This first-in-the-nation paid family leave program is being closely watched as a potential model for other states and the federal government. Paid Family Leave Insurance is a major attempt at chan...Drug shows activity against brain metastases
...n tumors shrank significantly in what was termed a partial response in 15 patients (6 percent). Across all 241 patients, there was a period averaging 15 weeks before the disease progressed again. About one-fifth of patients did not experience any worsening of their disease for 6 months or longer. Eric Wine...Researchers use MRI to predict recovery after spinal cord injury
...gists can better predict the likelihood of full or partial recovery of patients with acute spinal cord injuries (SCI), according to a study published in the June issue of the journal Radiology. "Our study demonstrates that the possibility and extent of neurological recovery after SCI can be predicted with...Dynamic sonography accurate in diagnosing muscle tears
...ded by hemotomas and the remaining 14 patients had partial tears, appearing as hypoechoic subtle lesions with relaxed muscle which looked like pseudo-tumors on contraction. According to the study, the healed tears appeared as highly reflective scar tissue. "We are successfully performing dynamic sonograp...Possible new breast cancer gene
...r of Cancer Biology at Penn. "Now we have gained a partial understanding of the molecular basis between cancer-causing BRCA1 failures to fix DNA damage versus normal BRCA1s ability to fix DNA damage." In this study, the researchers found Rap80 binds to the region of the BRCA1 protein that is necessary for ...New device for stroke patients improves walking
...e survivors, one common difficulty is foot drop, a partial leg paralysis that prevents the foot from lifting -- causing instability and difficulty walking. Now, a new high-tech rehabilitation device -- available in the New York Cityarea only at NewYork-Presbyterian Hospital/Weill Cornell Medical Center...Sleep apnea patients have greatly increased risk of severe car crashes
...s, during sleep. Periods of apnea end with a brief partial arousal that may disrupt sleep hundreds of times a night. Obesity is a major risk factor for sleep apnea. The study found that while in the general population men have more vehicle crashes than women, among sleep apnea patients, men and women crash ...The hepatitis C link: Diagnose, treat, transplant
...d by prior treatment status into non-responders or partial responders and randomized to three treatment group...lled 36 patients (PRC: 15; PC: 11; PR: 10) and the partial responder cohort had 21 patients (PRC: 3; PC: 9; PR: 9). For prior non-responder patients, an Ea...Sleep apnea increases risk of heart attack or death by 30 percent
...s, during sleep. Periods of apnea end with a brief partial arousal that may disrupt sleep hundreds of times a night. Obesity is a major risk factor for sleep apnea. The most effective treatment for sleep apnea is a technique called nasal CPAP, for continuous positive airway pressure, which delivers air throu...Sleep apnea may increase risk of diabetes
...s, during sleep. Periods of apnea end with a brief partial arousal that may disrupt sleep up to hundreds of times a night. Obesity is a major risk factor for sleep apnea. Emerging evidence also exists that sleep apnea is associated with hypertension, stroke and heart disease. The most effective treatment for...Some children are born with 'temporary deafness' and do not require cochlear implant
... He added that some of the children only develop partial hearing, which can be augmented with external hearing aids. Prof. Attias is now researching "temporary deafness" among young children, looking to find a way to identify those who will recover and those who will not....One pill may be better than two for treating patients with high blood pressure
...lts when varying the effectiveness associated with partial adherence from 0 percent to 100 percent of the effectiveness of full adherence. Researchers in the ValueMedics study used U.S. databases to estimate direct medical costs and adverse treatment outcomes over four years among adults with similar charact...New data shows once a day LAMICTAL XR is effective in patients with partial epilepsy
... is effective as add-on treatment in patients with partial epilepsy with and without secondary generalization...w once-daily, extended release formulation reduced partial seizures by 46 percent, while patients taking placebo experienced a reduction of 24 percent over the...Did drug reps encourage doctors to prescribe gabapentin for nonapproved uses?
...ly approved use of gabapentin was for treatment of partial seizures in adults with epilepsy, in combination with other drugs. However, gabapentin was used for many other conditions such as treatment of psychiatric disorders and management of pain. These researchers used the documents to research detailing an...Arsenic in chicken feed may pose health risks to humans, C&EN reports
...olon cancer, while low-level exposures can lead to partial paralysis and diabetes, the article notes. Use of roxarsone has become a topic of increasing controversy. A growing number of food suppliers have stopped using the compound, including the nations largest poultry producer, Tyson Foods, according to...Combined imaging approach may provide better identification of difficult-to-diagnose brain clots
...ache. "In cases where the patient has an ongoing partial or full blockage," Leach explains, "the blood clot organizes into a more solid lesion, forms connective scar tissue and can develop small vessels in an attempt to restore blood flow. This was very difficult to diagnose correctly using previous techni......en used as adjunct therapy for adult patients with partial epilepsy, fully eliminating seizures in 24 percent of tested patients. The occurrence of side effects was also low compared to other current treatment methods. No age- or gender-related differences were found in the effectiveness of the treatment. ...