Molecular change occurring during brain tumor progression also evident in breast cancer
...tissues," said Shikha Bose, M.D., an expert breast pathologist who participated in the study. "1 chain of laminin-2, -8 and -10 is detected in newly formed tumor vessels and might be important predictors for patient outcome."...Investigating 'brain shrinkage' in alcoholics
..., calling it critical to solving the puzzle. "The pathologist and neuroradiologist can identify the region of the brain to study, and the molecular biologist can take samples from these regions and look at the genes controlling structure and function and even identify individual proteins that might play a role ...PLoS Medicine refocuses world's attention on the tsunami, six months on
...st impossible task, argues the Sri Lankan forensic pathologist Clifford Perera. Was the humanitarian response guided by the best research evidence? Prathap Tharyan and colleagues from the Cochrane Collaboration say that some disaster response teams treated people with a psychological therapy called debriefing...Benign breast disease an important breast cancer risk factor
...l benign breast samples were evaluated by a breast pathologist unaware of initial diagnoses or patient outcomes and assigned to one of three categories of benign breast lesions -- non-proliferative, proliferative and atypical. This information was used to link the risk of subsequent development of breast cancer ...Researchers win Nobel Medicine Prize for discovering cause of ulcers
... Australian gastroenterologist Barry Marshall and pathologist Robin Warren were awarded the 2005 Nobel Medicine Prize today for discovering that the bacterium Helicobacter pylori ( H. pylori ) is responsible for stomach inflammation and ulcers. Each year, there are nearly half a million people newly diagnose...Altering time of breast biopsy may improve mastectomy reconstruction process
...e using SLNB, the sentinel node is quick-frozen; a pathologist then examines the node under a microscope. This me...detailed study called a permanent section. "If the pathologist does not see tumor in the lymph node on frozen section, there is still a chance that tumor may be fo...Errors in cancer diagnosis put patients in harm's way
...collection, and the proportion of errors caused by pathologist misinterpretation ranged from 5 percent to 50 percent. When pathologists reviewed specimens from other institutions they frequently disagreed with the assignment of error cause. Review of medical records showed that gynecologic errors resulted in ha...New evidence supports century-old theory of cancer spread
...r cells is not new. In the early 1900's the German pathologist Otto Aichel proposed that metastasis is caused by cancer cells fusing with macrophages. "There is now evidence to support all aspects of his proposition," said Pawelek. "Macrophages are among the most motile cells we have. By co-opting the macrophage...UCI receives major grant to develop 'gene signature' for prostate cancer prognosis
A UC Irvine pathologist who studies cancer cells has received a five-year, $9.5 million grant from the National Cancer Institute to develop a genetic method for predicting the outcome of prostate cancer at the time of diagnosis. It is one of the 10 largest research grants i...Researchers say criterion for diagnosing child abuse not always accurate
...seem, according to Patrick Lantz, M.D., a forensic pathologist from Wake Forest University Baptist Medical Center. "Contrary to what many doctors have been taught, we found that number and location of hemorrhages of the eye's retina aren't always proof of child abuse," said Lantz, who reported the results today ...BIDMC's Harvey Goldman, MD, receives distinguished pathologist award
...cine have included distinguished service as senior pathologist of the former Beth Israel Hospital, and chairman o...at BIDMC. "He has had an extraordinary career as a pathologist and educator and in the process has touched the lives of so many people in so many positive ways. We...Bone resorption cells offer drug targets for osteoporosis, rheumatoid arthritis, and more
Washington University pathologist Dr. Steven Teitelbaum describes how he and his col...an Society for Investigative Pathology (ASIP) to a pathologist with an illustrious career in research and continued productivity in the field. His Rouse Whipple A...M. D. Anderson: Setting the benchmark in brain tumor treatment
...has not told us that much," says Aldape, lead U.S. pathologist for the trial. "This is an unprecedented effort to understand precisely what is going on in brain tumors." Gilbert says that up to 20,000 genes and proteins can be characterized through this screening process, and the results will be compared ...AGA Institute presents cutting-edge research during DDW
...astritis. Dr. Marshall and J. Robin Warren, MD, a pathologist at the Royal Perth Hospital, later showed that patients could be cured of their peptic ulcer disease only when the bacteria were eradicated from the stomach. Additionally, a session on "Wnt Signaling in the Digestive Tract: From Development to Carci...A new guideline for screening apparently healthy individuals to prevent a heart attack
... said Dr. Erling Falk, a pioneering cardiovascular pathologist from Aarhus University in Denmark who coordinated the Writing Group of the SHAPE Task Force. Atherosclerosis, a metabolic and inflammatory disease that causes plaque build up in arteries, is responsible for nearly all cases of heart attack and most...Specimen radiography confirms success of MRI-guided breast biopsy
...iographs showed the lesion in question, helped the pathologist correctly identify the lesion while the patient was still in the operating room and helped the surgeon obtain negative surgical margins," said Dr. Erguvan-Dogan. In addition, "whole specimen radiography is able to correctly locate fractured biopsy n...Cancer survival compromised by poor staging methods
...en the surgeon who resects the lymph nodes and the pathologist who must analyze them. The work of either of these physicians may be impacted by patient characteristics, such as obesity. Prior to 1997, evidence suggested that the system of staging as put forth by the American Joint Committee on Cancer (AJCC) an...Second opinion yields treatment changes for half of patients
...e abnormalities. In addition, a dedicated breast pathologist can make a difference in how the cancer is staged, which in turn can affect treatment recommendations. In this study, the tumor board pathologists interpreted test results differently in 29 percent of patients. For some patients, this meant a change ...PET imaging identifies aggressive kidney cancers that require surgery
...ded as positive or negative for antibody uptake. A pathologist unaware of PET scan results then classified resected tumor specimens as clear cell renal carcinoma or otherwise. All patients were monitored for toxicity and the antibody infusion was well tolerated with no side effects or other adverse events rela...Exercise science principles strengthen swallowing rehabilitation
...about it," says Dr. Lori Burkhead, speech-language pathologist and clinical research scientist at the Medical College of Georgia Department of Otolaryngology Head and Neck Surgery. "We swallow in our sleep. Babies do it in utero. It is something we do without giving it much thought, but it's actually a very com...