Animal studies suggest vegetables may reduce hardening of arteries
...ment of plaques in the artery walls. "Although the pathways involved remain uncertain, the results indicate that a diet rich in green and yellow vegetables inhibits the development of hardening of the arteries and may reduce the risk of heart disease," said Adams. He said that a 37 percent reduction in a cert...DNA repair in mammal embryos is a matter of timing
... St. Jude team studied the roles of the two repair pathways using mice that lacked either the gene Xrcc2, which is critical for the HR pathway, or Lig4, which is critical for the NHEJ pathway....Preventing spinal cord injury during aortic surgery
...ive oxygen species and in initiation of cell death pathways during ischemia-reperfusion injury. In particular, the establishment of a correlation between the structural integrity and the function of mitochondria in ischemia-reperfusion injury is shown for the first time in an animal model of spinal cord inju...Early puberty may mean anxiety, abnormal eating behaviors later
...he development of the brain, when important neural pathways essential for behavioral and cognitive functions a...the development of the brain when important neural pathways essential for behavioral and cognitive functions are formed. It also is a time when teenagers and ev...Hopkins scientists use embryonic stem cells, new cues to awaken latent motor nerve repair
...ws that such cells can be made to re-trace complex pathways of nerve development long shut off in adult mammals, the researchers say. "This is proof of the principle that we can recapture what happens in early stages of motor neuron development and use that to repair damaged nervous systems," says Douglas Ke...Refined stem cell therapy helps paralyzed rats recover
...bryonic stem cells can be induced to create normal pathways for the generation of spinal motor neurons, and this activity can be encouraged by certain pharmacologic agents. The results could help victims of paralysis regain motor function. Based on this hypothesis, researchers led by Douglas Kerr, M.D., Ph.D....Cycles of cell death, proliferation key to liver cancer
... control of tissue renewal through the IKK and JNK pathways plays a key role in liver cancer in mouse models. One link between inflammation and cancer is known to involve the NF-kB pathway, which regulates gene expression. In research published in the journal Cell in 2005, Karin and his colleagues at UCSD im...Bazan to receive ARVO Proctor Medal
...the Proctor Medal for his elucidation of the lipid pathways in the retina, his discovery of the DHA derivatives named docosanoids, his work on the platelet activating factor in inflammatory responses, and his design of agents to prevent apoptosis arising out of this work. Bazan is Director of the Louisiana ...IADR and GlaxoSmithKline Consumer Healthcare announce winners of 2006 Innovation in Oral Care Awards
...ong emphasis on developing alternative therapeutic pathways and products to the more aggressive antimicrobial therapies currently used in many later-stage treatments for tooth decay and periodontal diseases." In its third year, the IADR/GSK Oral Care Awards received 25 applications from teams of researchers ...Researchers find molecular 'brake' to cell death
...cancer because tumor cells have adapted biological pathways to circumvent cell death, so many anti-cancer therapies focus on inducing apoptosis in these cells, Tang says. But the notion of how to push cancer cells to die has been flawed, Tang says. These new findings "overturn a scientific dogma so long ac...JCI table of contents: July 3, 2006
... Molecular Medicine, Berlin, discuss the signaling pathways involved in this disease and how they manifest the...ndings of this study in the context of other known pathways of cholesterol transfer, and steroid synthesis in a variety of tissues. TITLE: Liver X receptors reg...ESC recommends interdisciplinary collaboration in non-invasive imaging
...lop joint clinical services with common diagnostic pathways for patients with suspected cardiovascular disease...lop joint clinical services with common diagnostic pathways for patients with suspected cardiovascular disease, which are organised in collaboration between car...Einstein's Dr. Michael Brownlee receives prestigious new scholar award from JDRF
...ed that the four seemingly independent biochemical pathways found to contribute to hyperglycemia-induced damag... that normalizing free-radical levels inhibits the pathways through which cell damage occurs. Dr. Brownlee's current studies include clinical trials of benfot...Taking the wrinkles out of motoneuronal disease
...euronal diseases cause a degeneration of the nerve pathways controlling muscle activity. The diseases are severe and physically debilitating disorders which lead toprogressive weakness and wasting of muscles. Many of the diseases are incurable. Dr Meunier is developing botox to selectively deliver drugs to ...Duke researchers link newly discovered gene to hereditary neurological disease
...at play a potential role in governing the cellular pathways of neurodegenerative disease. By meticulously examining the DNA sequence of those genes, the researchers located mutations -- changes in the DNA sequence -- in the REEP1 gene among people who have hereditary spastic paraplegia but not in their unaffe...Protein potentially links diet, obesity and asthma
... emerging theme that an overlap exists between the pathways that regulate inflammation and those that govern metabolism. Finally, the study suggests that blocking aP2 function may be a novel approach for the treatment of asthma and other inflammatory lung diseases. ...Jefferson scientists show 'miracle' cancer drug Gleevec can be toxic to the heart
..., the researchers attempted to find the biological pathways involved in causing heart cells to die. They found that Gleevec appears to cause endoplasmic reticulum stress, which is initially a protective response by the cell, but if sustained, leads to cell death. They also found that treating mice heart cells...Slowing Alzheimer's disease by keeping mind and body active
...uenster, Germany -- Researchers have uncovered the pathways behind the protection offered by environmental sti...hat an enriched environment elicits protection via pathways that prevent A accumulation and enhance its clearance. The authors speculate that the alte...W.M. Keck Foundation announces 2006 class of Distinguished Young Scholars in Medical Research
...oRNA, regulates different genes and the biological pathways those genes control. She is focusing on a particular microRNA that may function as a tumor suppressor. Her work may contribute to developing microRNAs as less-toxic, targeted new therapies against cancer and other diseases. Each applicant was nomi......time. The researchers evaluated three different pathways involved in cell signaling, the complex system of ...l actions. It had previously been shown that three pathways (activated by vasoactive intestinal peptide, epidermal growth factor or phosphoinositide 3-kinase) a...