Bold three-stage brain operation for intractable seizures appears promising
...ant to treat children as early as possible because persistent seizures are associated with a host of serious learning and developmental problems." The report in the journal Pediatrics is entitled "Epilepsy Surgery in Young Children with Tuberous Sclerosis: Results of a Novel Approach." The authors are Dr. ...Inability to complete quarter-mile walk is significant predictor of death and poor health in elderly
...o stop if they experienced any signs of fatigue or persistent rapid heart rate. Of the 2,680 elderly people eli...rmer group also had a significantly higher risk of persistent limitations in their mobility and related disabilities than did those who completed the full 400-met...FDG-PET accurate for evaluating lung tumor destruction from radiofrequency ablation
...ts for the 10 patients, follow-up PET demonstrated persistent tumor activity. Two of the patients showed no activity on the follow-up PET, suggesting complete destruction of any active tumor. One patient had no definite change in the appearance of the mass, and another had a smaller lesion on follow-up PET. ...Rapid lung function decline raises risk of death and hospitalization
...t cause of hospitalization and death, results from persistent obstruction of the airways associated with either severe emphysema or chronic bronchitis. In emphysema, the tiny air sacs of the lung (alveoli) become enlarged and their walls are destroyed. In chronic bronchitis, the bronchial glands enlarge, causin...Melatonin improves mood in winter depression
...ur years of study, they concluded that, similar to persistent jet lag, circadian misalignment is a major part of SAD. Most patients, typically phase-delayed types or "night owls," have misalignment that responded best to taking low-dose melatonin in the afternoon or evening. A longer-than-expected subgroup of ...New drug could reduce tissue damage after heart attack
...heart attack. Patients with the greatest and most persistent increases in CRP concentration suffer higher mortality, and CRP is always deposited in and around the damaged heart tissue. Inflammation contributes significantly to the extent of heart attack damage and this can be exacerbated by CRP. The UCL team...JCI table of contents, April 20, 2006
...ents of some of the glomeruli. This results in the persistent release of protein from the urine and progression to renal failure. Despite a growing understanding of the genes involved in FSGS, a clear genetic diagnosis cannot be made in the vast majority of patients. In a study appearing online on April 20 in a...Inhaled steroids preferred over cromolyn to treat asthma
... are preferred first-line therapy for treatment of persistent asthma, which requires daily therapy. But we also ... Physicians recommend both types of medication for persistent asthma, but individual studies disagree about which type of medication works best, the reviewers fou...Endurance walking test distances improved significantly for COPD patients
...these patients," said Dr. Laude. COPD results from persistent obstruction of the airways associated with either severe emphysema or chronic bronchitis. In emphysema, the tiny air sacs of the lung (alveoli) become enlarged and their walls are destroyed. In chronic bronchitis, the bronchial glands enlarge, causin...JCI table of contents, April 6, 2006
...clinical symptoms. However, this brain-restricted, persistent viral disease makes the mice susceptible to T cell-mediated pathology and clinical disease following a subsequent peripheral challenge with a related LCMV virus. The authors hypothesize that the organ-restricted infection results from either an infec...Trial shows vaccine against cervical cancer provides long-term protection
... team found that the vaccine was effective against persistent and new infections and protected against infection with HPV-45 and 31--the third and fourth most prevalent oncogenic types of HPV. The vaccine also had a good long-term safety profile and provided substantial long-term protection against cancerous ce...Photodynamic therapy is an alternative to removal of esophagus
...tant to go to your doctor, if you are experiencing persistent or severe heartburn. If acid reflux is controlled, you may not develop Barrett's esophagus." Preventing Barrett's esophagus could be a matter of life or death: Those with Barrett's esophagus may be 30 times more likely than the average person to deve...Using HPV testing to screen for cervical cancer
...t outcome and can easily be automated." Since only persistent HPV infections are thought to be associated with pre-cancerous lesions, they suggest that procedures need to be developed for repeat testing to detect infections that may be transient, especially in younger women. They also suggest performing the HPV...Transition to menopause associated with new onset of depressive symptoms
...e identified risk factors are associated with more persistent depression," the authors conclude....ROZEREM (ramelteon) showed significant reduction in time to fall asleep
...ent in the time it took to fall asleep (latency to persistent sleep, or LPS). Results showed that a statistically significantly greater percentage of adults with chronic insomnia treated with ROZEREM 8 mg demonstrated at least 50 percent LPS reduction compared to those who received placebo at week 1 (63 perce...Doctors must work together better to improve survival in teenage and young adult cancer patients
...s, so that they realise that if a young person has persistent or worrying signs or symptoms, they should seek medical help. Even more importantly, we need to make sure that the medical profession is well educated as to the meaning of such signs and symptoms and do not fail their patients by delays in diagnosis...Pregnant women should not ignore breast cancer symptoms
...oms can include nipple discharge, skin changes and persistent or progressive unilateral breast swelling or engorgement....Researchers at Vanderbilt-Ingram Cancer Center study exercise to curb 'chemo brain'
...d chemotherapy in the last five years, experienced persistent memory or cognitive problems since chemotherapy, does not already exercise regularly, and has no history of brain cancer, heart disease, or a serious medical condition that could be worsened by exercise, is eligible for the study. Matthews said exer...New study reports increased response to therapy with no added toxicity in treatment of ...
...ty were from one institution) who had recurrent or persistent epithelial ovarian carcinoma. The final analysis included 39 women in the topotecan/control arm and 30 women in the thalidomide/topotecan arm. The women in the thalidomide/topotecan arm: Had a 47 percent overall response rate compared to 21 perc...Vol. 42, No. 5 JRRD tipsheet: Focus on spinal cord injury and prosthetics
...njury, upper-limb pain in tetraplegia, and severe, persistent pain) were stable in chronic SCI. They conducted two surveys 18 months apart to examine the stability of pain characteristics and pain-induced interference with sleep and daily activities. While pain locations, pain descriptors, pain intensities, and...