Anemia and tropical diseases; Is pharmacogenomics ready for the clinic?
...wen and colleagues review the limited successes of pharmacogenomics (individualized drug dosing based on hereditary factors) and discuss the remaining challenges to its widespread clinical use. Citation: Swen JJ, Huizinga TW, Gelderblom H, de Vries EGE, Assendelft WJJ, et al. (2007) Translating pharmacogenomics: Ch...St. Jude projects 90 percent cure rate for ALL
...ent," Evans said. "That's why the breakthroughs in pharmacogenomics made at St. Jude and elsewhere are so important. T...t in diagnosis and treatment made possible by MRD, pharmacogenomics and new drug therapies has shifted the focus in ALL therapy toward reduction of both the immediate a...Mayo Clinic first to use pharmacogenomics to treat inherited kidney disorder of children
...CHESTER, Minn.-- Mayo Clinic researchers have used pharmacogenomics to develop a test and treatment for an inherited kidney disorder that can cause organ failure in children and young adults. The findings appear in the current issue of the journal Kidney International ( http://www.blackwell-synergy.com/links/doi/10....Gene expression pattern predicts multiple drug resistance, treatment failure in pediatric leukemia
...s University Hospital in Hamburg, Germany. Using pharmacogenomics techniques to assess gene expression levels in ALL cells, researchers identified 45 genes closely linked with leukemic cells' ability to resist treatment by at least two of the most widely used antileukemic drugs. The drugs tested were prednisolone, ...