Tag: "phase" at medical news
DNA vaccine against multiple sclerosis appears safe, potentially beneficial
...compared with placebo. Based on these results, a phase
2b triala randomized clinical trial in approximately 290 patientsof BHT-3009 is already under way. If successful in MS, antigen-specific DNA vaccines can be developed for prevention or treatment of related diseases, such as type 1 diabetes mellitus, ...
New study shows promise in reducing surgical risks associated with surgical bleeding
...remost interest to surgeons. The results from this phase
III trial show that we can stop bleeding in 95 percent of patients within 10 minutes and do so without introducing foreign proteins that can carry greater risk of development of antibodies, said William C. Chapman, MD, FACS, Department of Surgery, Wa...
To gain muscle and lose fat, drink milk: study
...orking out, drink milk. As reported in the first phase
of the study, the milk drinking group came out on top in terms of muscle gain with an estimated 40 per cent or 2.5 pounds more muscle mass than the soy beverage drinkers. In addition, this group gained 63 per cent or 3.3 pounds, more muscle mass tha...
World's largest respiratory health study launches next phase
...health research study, is launching a new research phase
focussing on the 21,000brothers and sisters of the...1961 throughschools across the State. In this next phase
of the study we are hoping to contact all the brothers and sisters of thoseoriginal 8,500 children w...
Why women get more migraines than men
...udy results appear to be independent of a specific phase
of the cycle, according to Charles. We didnt mon...graine that may not be simply linked to a specific phase
of the menstrual cycle. These results are exciting, Charles said, because they may represent a mod...
Shining light on pancreatic cancer
...lthough the researchers hope to use the next trial phase
to test individuals with serious pancreatic diseases that are not cancer to see if the changes are truly unique to cancer. Eventually, the researchers hope to expand their study to breast cancer, lung cancer and other variations of the disease. Whi...
Trials underway for 'essential' new TB vaccine
...ety trials in The Gambia, the drug has now entered phase
II trials in The Western Cape in South Africa, where the incidence of TB disease in infants is 1 in 100 (despite BCG vaccination). It has first been tested in HIV negative adult volunteers and these trials are now being stepped down into adolescents,...
SAGE to publish British Journal of Infection Control
...tish Journal of Infection Control moves into a new phase
in September 2007, as we embark on an exciting partnership with SAGE Publications. The ICNA believes this publishing partnership will allow us to strengthen and grow the reputation of the BJIC as a respected professional journal of value to all profe...
MU researchers find mechanisms that may unlock answers to Alzheimer's disease
...ood and Natural Resources, are entering the second phase
of an $11 million project aimed at identifying the...can harm neurons and other brain cells. The next phase
of the study includes three projects. Sun will study mechanisms whereby A-beta affects phospholipase...
Study shows Diachrome improves blood sugar control in people with type 2 diabetes
...blication of this landmark study, which followed a phase
III pharmaceutical-equivalent design, reinforces our belief that Diachrome will become a standard tool for public and private healthcare professionals charged with managing the growing epidemic of type 2 diabetes, said Paul Intlekofer, CEO of Nutriti...
Research shows survival benefit for leukemia patients treated with arsenic trioxide
...atients in the U.S. and Canada participated in the phase
III study over a six-year period from June 1999 through March 2005. The study was sponsored by the National Cancer Institute (NCI) and led by one of its cooperative groups, the Cancer and Leukemia Group B (CALGB). The Comprehensive Cancer Center at ...
Adding radioimmunotherapy to chemo may help patients with lymphoma
...a positive PET scan after the initial chemotherapy phase
of treatment relapsed. Of the 34 patients whose early PET scans were negative, none have relapsed to-date. We were surprised to find that PET was a useful tool in determining those patients who were at highest risk for their diseases to relapse. O...
Phase II study shows combination improves survival of metastatic melanoma patients
...ortal/site/ASCO ) (ASCO) Annual Meeting. In this phase
II clinical trial of 53 patients, tumor growth was delayed by almost six months, whereas, typically, these cancers begin spreading again eight weeks after chemotherapy treatment, researchers say. The researchers from Mayo Clinic ( http://www.mayo....
Liver cancer patients with high serum levels of hepatitis B virus face poorer outcomes
...ents. They studied 188 patients participating in a phase
III randomized controlled trial comparing two different chemotherapy regimens. One hundred and seventy patients (92 percent) had evidence of HBV infection. Of these, 125 had sera available to determine HBV DNA levels and were included in the study. ...
Doctors conclude temsirolimus is effective new treatment for advanced renal cell carcinoma
The results of a phase
III, randomized clinical study involving patients with advanced renal cell carcinoma and poor prognostic features show temsirolimus improved overall survival when compared to the current treatment for this stage of disease. The study, led by Gary R....
Innovative device to treat brain cancer shows promise in early studies
...udes the results of cell culture, animal and early phase
human trials, appears in the current issue of the Proceedings of the National Academy of Sciences (PNAS). The device, called the Novo-TTF, uses electrical fields to disrupt tumor growth by interfering with cell division of cancerous cells, causing...
Increasing radiation dose shortens treatment time for women who choose breast sparing treatment
...he cosmetic result," explained Freedman. "In this phase
II study, women reported acceptable side effects, and the cosmetic result was similar to the longer six-week treatment course." The study included 75 women treated with 2.25 Gy for 20 days (versus 2 Gy per day with conventional therapy) and a 2.8 Gy...
New hope for severe heart disease patients
Funded by the MBF Foundation, the second phase
of the project will test whether using the G-SCF h...Professor Bob Graham, said evidence from the first phase
of the study into the safety of the G-SCF treatment gave hope to the patients taking part. Many of t...
Experimental gene therapy 'abolishes' arthritis pain and lessens joint damage
...e gene therapy with a different vector in the next phase
of experiments. Kyrkanides is partnering with rese...roof of principle needed for the team to apply for phase
I human clinical trials, perhaps within 18 months, Kyrkanides said. Early results, while not yet pub...
Rosiglitazone -- Seeking a balanced approach to avoid panic among patients
...tion can reasonably await the results of RECORD a phase
III trial specifically designed to analyse cardiovascular events connected to use of rosiglitazone. The Editorial says: "Until the results of RECORD are in, it would be premature to overinterpret a meta-analysis that the authors and NEJM editoriali...
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