UC Davis researchers find added benefit of statins in those at high risk for heart disease, diabetes
...atins work at the molecular level. Compared to the placebo group, monocytes from patients exposed to statin produced less interleukin-6 and TNF, two critical molecules in insulin resistance and the development of cardiovascular disease. In addition, the researchers made the novel observation that in patients...Selective serotonin reuptake inhibitors antidepressants and risk of violent behavior
...e British regulatory authorities. A summary of placebo controlled trials in children and adults showed th... given paroxetine, compared with 20 of 6,455 given placebo (0.31%) had what was called a "hostility event". In their submissions to the Committee on Safety ...Stubborn ulcerative colitis responds to arthritis drug, review finds
...tudies, patients were given either infliximab or a placebo for moderate and severe cases of ulcerative coliti...gle infusion of infliximab was more effective than placebo in reducing the need for colectomy within three months. Serious side effects were "not common" in ...New SSRI effective for the treatment of moderate-to-severe premature ejaculation
...rtners. Patients were randomly assigned to receive placebo (870), 30 mg dapoxetine (874), or 60 mg dapoxetine (870) and were instructed to take a dose 1-3 hours before sexual intercourse. On average, at the start of the study, the men ejaculated under a minute after penetration. The researchers found that af...Early trial shows H5N1 influenza vaccine safe and effective in humans at low doses
...unteers aged 18-60 years to receive two doses of a placebo or the whole-virus vaccine at 1.25, 2.5, 5, or 10 ...y of reported side-effects between the vaccine and placebo group. The frequency of side-effects reported with the whole-virus vaccine was also similar to that ...Epilepsy medication proving ineffective over time
...Research is currently being done on the effects of placebo and conditional tolerance (a mental, conditioned-response effect that the mind has over the body). Doctors are also studying the effects of lower initial and target doses of AEDs. The possibility exists that many patients are being initially over med...Unlocking colon cancer with key of prevention
...ose of celecoxib (approximately 930 subjects) or a placebo (nearly 630 subjects). Subjects received colonosco... the cumulative rate of adenoma development in the placebo group was 49.3 percent (a 36 percent reduction). Celecoxib administration was associated with a 50 p...Study finds that vioxx reduces the risk of colorectal polyps
...yps, the subjects were randomized to receive daily placebo or 25 mg rofecoxib on a daily basis. The primary e...ower recurrence rate of adenomas than those taking placebo (41 percent vs 55 percent; p Baron says that patients treated with rofecoxib experienced more serio...Rofecoxib significantly reduces the risk of recurrence of colorectal polyps
...ower recurrence rate of adenomas than those taking placebo (41 percent vs 55 percent; p About the StudyThe ...polyps, patients were randomized to receive either placebo or 25 mg rofecoxib (the average daily recommended dose) on a daily basis. The primary endpoint was a...M. D. Anderson teaches the art of aromatherapy to soothe and heal
...y due to the fact that it is difficult to create a placebo and every person is different in their nasal sensitivities and skin absorption rates," says Perez. In the future, however, she would be interested in designing research to examine how aromatherapy can be used to treat/heal burns caused from radiation...Experts add to growing warnings about asthma drug
...ee among another 13,000 individuals who received a placebo during a 28-week treatment period. Other studies have suggested that some people have a genetic variation that causes them to respond negatively to the class of medications that includes salmeterol, Weinberger said. The concern about salmeterol an...Idursulfase is effective treatment for Hunter syndrome, clinical trial concludes
...were enrolled in the clinical trial. Some received placebo infusions, some received weekly infusions of Elapr...erage, 37 meters farther within 6 minutes than the placebo group. In addition, the weekly dosing group experienced an increase in forced vital capacity compare...New medication appears effective in helping smokers kick the habit
...ly, or 1 milligram twice daily for six weeks, plus placebo for one week; to 150 milligrams of sustained-relea...n hydrochloride twice daily for seven weeks; or to placebo for seven weeks. The authors report that varenicline, in combination with brief behavioral counsel...Heart failure drugs may be beneficial for patients with hardening of the arteries
...nts had been randomly assigned an ACE inhibitor or placebo for an average of 4.5 years. They found that ACE inhibitors reduced the risk of a range of outcomes including all-cause mortality (8.9 vs 7.8%), non-fatal heart attack (6.4 vs 5.3%), stroke (2.8 vs 2.2%), and heart failure (2.7 vs 2.1%) when compared...Aggressive reduction in cholesterol levels can reduce risk for stroke by 16 percent
... stroke (2.3 percent), compared to patients taking placebo (1.4 percent). However, the overall benefit in terms of reducing the risk of stroke was still significant despite this increase, and there was no difference in the number of deaths from hemorrhagic stroke between the two treatment groups. Every yea...Experimental medication kicks depression in hours instead of weeks
... either a single intravenous dose of ketamine or a placebo (inactive compound). Depression improved within on...enefits seven days later. Participants receiving a placebo infusion showed no improvement. One week later, participants were given the opposite treatment, unle...Study suggests anesthetic agent may have rapid antidepressant effects
...mly assigned to receive either the ketamine or the placebo infusion first. They underwent tests to assess th...fusion, patients who received ketamine rather than placebo showed significant improvement. The effect lasted through the following week. On the day after tre...Protein-added sports drinks don't boost performance during exercise, study finds
...nk, a sports drink supplemented with protein, or a placebo drink that provided no energy. The drinks were sim... sports drink improved performance compared to the placebo drink -- confirming prior research -- but there was no additional benefit of protein supplementation...Placebo study frames depression treatment puzzle
...me and regional changes in brain activity during a placebo lead-in phase prior to antidepressant treatment. ...tudy, all subjects received blinded treatment with placebo for one week prior to receiving antidepressant medication. A "placebo lead-in" phase is commonly use...New data demonstrate effectiveness of LAMICTAL (lamotrigine) as adjunctive therapy
... patients receiving LAMICTAL and 40 percent in the placebo group (p=0.044). The median PGTC seizure counts per month were significantly improved for all treatment phases in patients receiving LAMICTAL compared to placebo. The most commonly reported adverse events in this analysis were headache (10% LAM...