New long-term data suggests Abatacept treatment
...as found to be significantly better than 1 year of placebo followed by 1 year of abatacept. Radiographic progression in the abatacept group slowed during year 2 vs. year 1. "The long term extension of the AIM study shows that 2 yrs of abatacept treatment slowed progression of structural damage in rheumatoid ...Tocilizumab study offers new hope for children with arthritis
...the encouraging results of the first double-blind, placebo controlled trial for tocilizumab at the Annual European Congress of Rheumatology in Amsterdam today (Thursday 22 June). Juvenile Idiopathic Arthritis (JIA) is a relatively rare disease, affecting 30 to 150 children per 100,000 per year in Europe.1 "...Cherry juice may prevent muscle damage pain
...ercise and for four days afterwards, or to drink a placebo juice containing no cherries. The 12-ounce bottle ...gain two weeks later, with those who had taken the placebo juice taking the cherry juice blend instead, and vice versa. The other arm was also used. There was ...Growth hormone stimulators improve physical function in older adults
...he study, and were divided into groups receiving a placebo or one of four different levels of an oral growth hormone secretagogue (GHS), which stimulates the secretion of human growth hormone. Researchers measured the participants' fat and lean body (muscle) mass, as well as their performance in physical tes...Media availability: Drug found to help scleroderma patients
...pill commonly used to treat cancer patients, or to placebo for one year. Participants were assessed periodically for an additional year after treatment. Negative side effects, such as low white blood counts and complications from infection, were more common among participants treated with the drug; however, ...Hormones could be prescription for living longer
...physical functioning, participants received either placebo or various oral doses of the growth hormone stimulator (GHS) capromorelin, an investigational medication discovered and developed by Pfizer Global Research and Development. Compared to placebo, GHS at any dose prompted an acute GH peak and an increas...Rheumatoid arthritis can be prevented if the timing is right
... versus Placebo Treatment-study) is a double-blind placebo controlled randomized multicenter trial in 110 patients with undifferentiated arthritis, which means they have arthritis but the exact diagnosis is undetermined. The aim of the study was to determine whether the patients would benefit from treatment ...Studies of married couples, soccer and hockey teams focus on brain's response to stress
...tocin via nasal spray, while the others received a placebo intranasally. From saliva samples, the team monitored production of a stress hormone called cortisol. Standard questionnaires were used to measure personality traits and document how participants perceived the quality and social support of their rela...Tip sheet, Annals of Internal Medicine, April 20, 2006
...unction and slowed joint damage when compared with placebo (Article, p. 865). Those receiving abatacept also ... needed for FDA approval, compares a new drug to a placebo (sugar pill) rather than to the best alternative drug, which is what would be most useful to practic...ROZEREM (ramelteon) shown to be effective in a first-night-effect model of transient
...ndomized to receive either ROZEREM 8 mg, 16 mg, or placebo 30 minutes before bedtime in this double-blind, parallel-group study designed to evaluate the efficacy of ROZEREM in a first-night-effect model of transient insomnia. Sleep was assessed with overnight polysomnography (PSG) a test that records brain...Common asthma inhaler causing deaths, researchers assert
...the beta-agonists died, compared with three in the placebo group, over a six-month period. "In total, there ...matory drug compared with asthma patients taking a placebo and an anti-inflammatory drug by itself. Of the 19 studies surveyed in the meta-analysis, the large...Risk of ventilator-associated pneumonia cut significantly
...hird group of 130 ventilated patients were given a placebo paste. In comparison to the placebo, the chlorhexi...ed with ventilator-associated pneumonia: 23 in the placebo group (18 percent); 13 in the chlorhexidine group (10 percent); and 16 in the combination group (13 ...Stopping inhaled corticosteroid use causes no problems in cystic fibrosis patient users
...ot. "Replacing the inhaled corticosteroids with a placebo was found to be safe as there was no significant increase in lung-related adverse effects leading to withdrawal from the study, nor an increased need for oral corticosteroids," said Dr. Balfour-Lynn. The researchers stressed that they were not advoca...Natural pine bark extract relieves muscle cramp and pain in athletes and diabetics
...ycnogenol. Results indicated participants who took placebo experienced no decrease in pain. Cramps are a common problem for people of all ages, ranging to the extreme fit and healthy to people who suffer from health problems. Previously, magnesium was hailed as the natural approach for relieving muscle cram...Increase in counterfeit antimalarial drugs prompts call for crackdown, better detection
...urther deceive patients and doctors by producing a placebo effect, Fernandez said. "For example, some of the counterfeit tablets we analyzed contained acetaminophen that would reduce a fever, or the antibiotic erythromycin, or even early-generation anti-malarials that are no longer effective." The researcher...Consumption of fish oil does not appear to protect against abnormal heart rhythms
...e 2 grams/day of fish oil in capsules (n = 273) or placebo capsules (n = 273) for a median (midpoint) period ...fish oil group and 81 patients (30 percent) in the placebo group received appropriate ICD intervention for VT or VF. Event-free survival did not substantially...Use of anti-depressant does not decrease risk of relapse for patients with anorexia nervosa
... New York, and colleagues compared fluoxetine with placebo to determine the rate of relapse and behavioral re...andomly assigned to receive fluoxetine (n = 49) or placebo (n = 44) and were treated for up to 1 year as outpatients. The researchers found that similar perce...Acupuncture relieves symptoms of fibromyalgia, Mayo Clinic study finds
...study convince me there is something more than the placebo effect to acupuncture," says David Martin, M.D., Ph.D., lead author of the acupuncture article and a Mayo Clinic anesthesiologist. "It affirms a lot of clinical impressions that this complementary medical technique is helpful for patients." Increasin...New results from the landmark PROactive trial
...gnificant risk reductions with ACTOS compared with placebo for the heart attack endpoint (23 percent, P=0.046... endpoint, compared with 409 (15.5 percent) in the placebo group. Additionally, 108 (4.1 percent) ACTOS patients had a myocardial infarction, compared to 140 (...Repeat corticosteroids for pregnant women at risk of preterm delivery could be beneficial
...receive a repeat injection of corticosteroids or a placebo every week until 32 weeks of pregnancy, if they re...%) in the repeat corticosteroids group than in the placebo group. Babies exposed to repeat corticosteroids also needed less oxygen therapy and help breathing. ...