New kidney cancer drug response rate is more than double that of standard treatment
...se, the median duration of partial response was 10 plus months. Eight of the patients remain progression-free, including two whose tumors became operable as a result of the treatment. The median time to progression was 8.7 months; the median survival was 16 months; six patients remain on therapy. In a s...Vitamin D, taxotere combination promising for advanced prostate cancer
...d more frequently in subjects receiving the DN-101 plus docetaxel combination (63 percent) versus docetaxel alone (52 percent). While the difference between the two arms did not reach statistical significance (p=0.07), the combination results represent an historically strong PSA response. Six months into ...Study demonstrates longest reported survival rate for locally advanced lung cancer patients
...r chemotherapy drugs -- cisplatin and etoposide -- plus radiation therapy. Among patients treated with the regimen, 29 percent were still alive after five years versus 17 percent of patients from a previous study, SWOG-9019. Patients in the earlier study received the same chemoradiation without docetaxel....Mayo researchers to announce new findings about promising early-stage breast cancer treatment
...m breast cancer. This intervention -- chemotherapy plus trastuzumab -- essentially changes the natural history of the disease," says Dr. Perez. The National Cancer Institute (NCI) sponsored two large, multicenter clinical trials studying more than 3,300 women with breast cancer between February 2000 and A...Dermatologists use immunotherapy to treat warts
...n. Warts were injected with antigen alone, antigen plus interferon alfa-2b (a chemical produced by the immune system), interferon alfa-2b alone or normal saline. Patients who had more than one wart were also tested for an immune response to HPV. Because interferon alfa-2b had no impact on the results, the...Randomized trial of two therapies for acute lymphocytic leukemia finds survival advantage
... compared with patients on a standard, vincristine plus prednisone-based regimen. Mark A. Weiss, MD, a leu... after two years. Patients treated with cytarabine plus high-dose mitoxantrone appeared to have a survival advantage at three, four, and five years. Thediff...Breast cancer chemotherapy regimen associated with life-threatening complications
The chemotherapy regimen of doxorubicin plus docetaxel, used to treat breast cancer in a clinic...hrough January 2003. Patients received doxorubicin plus docetaxel, or doxorubicin plus cyclophosphamide, given postoperatively for 4 courses. The trial was ...Bones don't pay a price when fat is lost through exercise
...robic exercise on a treadmill, bicycle or stepper, plus weightlifting, subjects experienced better overall fitness and fat loss without much change in bone mineral density. A more detailed analysis revealed slight gains in bone mass, of 1 percent to 2 percent, for those who exercised hardest and showed t...New NIAID grants strengthen national biodefense and emerging infectious diseases research network
...tium whose members include five other universities plus small business partners; it also includes substantial collaboration with the Centers for Disease Control and Prevention. The addition of these two new RCEs expands the network's scientific reach to cover some poorly understood diseases and new resear...Prescription of heroin is less costly for society
Prescribing methadone plus heroin to chronic, treatment resistant addicts is ... They were randomised to treatment with methadone plus heroin (experimental group) or with methadone alone (control group). After one year, data from 430 p...Chemotherapy options improve for patients with advanced colorectal cancer
... shown that a chemotherapy regimen of capecitabine plus oxaliplatin (CAPOX) is as safe and effective as infusional 5-fluorouracil/folinic acid plus oxaliplatin (FUFOX) in the first-line treatment of metastatic colorectal carcinoma (MCRC). The findi...Johns Hopkins team finds 'ancestral' hepatitis-C virus at the root of evolution in infections
...y injections of pegylated interferon for one year, plus twice daily doses of oral ribavirin. While some patients recover on their own, with their immune system attacking the virus and clearing it from the body, most do not. Scientists have not yet determined why this happens in some patients and not in ...Risk of heart attack may increase with certain anti-inflammatory drugs
...en, diclofenac, naproxen, celecoxib and rofecoxib, plus a host of other less commonly prescribed anti-inflammatories. The findings were adjusted to allow for several other heart attack risk factors including age, obesity, and smoking habits. Importantly, they also adjusted for whether the patient alread...Nutritious frozen foods can play role in weight-loss programs
... the second diet ate two packaged entrees each day plus recommended servings from the food pyramid. Both diets contained about 1,700 daily calories with equal amounts of carbohydrates, protein and fat. Subjects in the packaged-entree group chose from 24 varieties of Uncle Ben's? bowls, a brand of frozen e...Invasive treatment may be more effective for heart attack patients presenting late to hospital
...y (n=182) based predominantly on coronary stenting plus the intravenous medication abciximab or a conventional conservative treatment strategy (n=183), which included an intravenous infusion of heparin. The researchers found that the final left ventricular infarct size was significantly smaller in patien...Avoiding amputation: Early infection intervention can save feet & legs
... antibiotics alone are not as effective as surgery plus antibiotics, both for healing wounds and saving limbs," says Henke. "It also suggests that diabetic patients, especially those with PVOD, have a very high chance of developing osteomyelitis -- and that these patients should be considered for aggressi...Elevated CRP can foil diet's ability to lower cholesterol
... the next six weeks, they were fed the Step 1 diet plus 25 grams of soy protein or milk protein, after which their blood samples were drawn. The participants then took a two-week break and ate their usual diet before returning to eating only foods from the research kitchen. In the final 6 weeks of the...Italian law on ART brings problems for doctors and patients
...nancy rates before the law (fresh embryo transfers plus frozen embryo transfers) with those after the law (fresh embryo transfers plus the transfers of embryos obtained from frozen and thawed oocytes), we saw a statistically significan...Johns Hopkins scientists use gene therapy to prevent heart arrhythmias from stem cell transplants
...00 new cases of heart attack in the United States, plus an additional 300,000 cases of recurrent heart attack. More than 3 million Americans suffer from congestive heart failure, a common target of the myoblast stem cell therapy. In the study, Marbn and his team created a simulation of stem cell transpla...Takeda submits new drug application for combination type 2 diabetes medication
... to treatment with diet and exercise alone or diet plus insulin. Patients should always talk with their health professional about all the prescription and over-the-counter medications and dietary supplements they are taking before starting a new prescription....