Tamoxifen discontinuation rates surprisingly high in clinical practice
... an inherently biased data collection method in a population accustomed to chronic medications. Led by Thomas I. Barron, M.Sc. of the Department of Pharmacology & Therapeutics at Trinity College Dublin & St James's Hospital, Dublin, researchers reviewed pharmaceutical data from a national database of 2816 wome...Drug resistance in an influenza pandemic
...s with the intent to treat a large fraction of the population is a key part of pandemic preparedness of many countries. However, it is known that influenza viruses can develop resistance to these drugs. New research by Marc Lipsitch and colleagues (Harvard University) suggests that wide-spread use of antiviral ...Experts urge strongest isolation for new drug-resistant tuberculosis cases appearing in South Africa
...ing XDR-TB before it spreads more generally in the population globally." "We would not argue for forcible treatment of MDR-TB or XDR-TB patients, simply restriction of mobility rights of such individuals," the authors say, adding that detained patients need appropriate legal council, given the uncertainty of t...New international study to test exercise in heart failure patients
...uced heart contractions). He added, "The patient population enrolled in this trial will be a broad representation of heart failure patients, including large numbers of women, minorities and people from low socio-economic status." "The HF-ACTION trial has been designed so that if the intervention is benefic...New fat, same old problem with an added twist?
... fat consumed, underlying genetics of the specific population examined, or some unknown factor, requires further study because the apparent adverse impact on insulin metabolism is a troubling finding," he added....Study suggests hip fractures not caused by benzodiazepine use after all
...oked for changes in hip fracture rates in a stable population of more than 90,000 Medicaid recipients age 65 and older before and after a policy was implemented in New York in 1989 requiring benzodiazepine prescribing on triplicate forms. Since then, all physicians in the state are required to obtain, pay for, ...Study demonstrates long-term durability of Plicator procedure
...e years is that 55 percent of the original patient population had complete symptom relief." Pleskow's goal is to look at the data again in two years. He doesn't anticipate much drop-off in numbers. In fact with time, he anticipates better results, because this study reflects the early experience of the Plicator...Hospital death rate study reveals wide variations
... together with official discharge and death rates, population statistics and insurance plan data they discovered that a number of factors accounted for 45 per cent of the variation in death rates. "Our research underlines the need for hospitals to look as carefully at staffing structures and care processe...Resurgence and spread of syphilis in China is a rapidly increasing epidemic
... a substantial majority of men and a large migrant population of male workers, the report says. Changing social ...f syphilis in China for 20 years means the general population of young, sexually active individuals has no natural immunity to the disease, according to the autho...Improved adherence to certain medications associated with longer survival following heart attack
...nce-based medications predicts better survival, no population outcome study has attempted to differentiate whether these associations are attributable to the drug's biological responsiveness (drug effect) or to the adoption of healthier lifestyles that often accompany adherent behaviors (healthy adherer effect)...High level of cardiac biomarker may help predict risk of CVD events in patients with heart disease
...cation for cardiovascular events among the general population and among high-risk individuals is of considerable interest because of the potential to help guide use of primary and secondary preventive therapies. Brain-type natriuretic peptide (BNP; consisting of 2 or more amino acids) and the amino terminal fra...Pancreatic cancer surgery five-year survivors 65 and up live nearly as long as anyone
..."actuarial" or estimated survival of the general population beginning at age 70. Reporting in the journal Surgery, they found that 201 patients (23 percent) lived five years after surgery, at least half of whom were 65 years old or older at the time of surgery. Of those five-year survivors, an estimated 65 ...New Congress should focus on covering the uninsured, reducing health costs, according to new survey
... reducing the proportion of the uninsured under-65 population from 18 percent to 5 percent is an achievable and desirable goal for policy action within the next 10 years. The survey of leading health care experts with a diverse range of professional and ideological perspectives is the ninth in a series by The...Youth are receiving shorter inpatient stays for mental health treatment
...entionally harmed themselves. The total number and population rate of discharges did not change, but the total number of inpatient days and the average cost per visit each fell by approximately one half. They also report that transfers to short-term, nursing, and other inpatient facilities declined. "During...Binge drinking, gender and clinical depression
... than among men." Researchers conducted a general population telephone survey of 6,009 males and 8,054 females aged 18 to 76 years. The study included four types of alcohol measures given for both the past year and the week prior to the survey: frequency of drinking, usual and maximum quantity per occasion, o...Minorities and colorectal cancer screening: Phone them and they will come
...pulation. The study focused on a mainly minority population in the New York City metropolitan area. The 456 pa... among groups who are less likely than the general population to have participated in screening."...Clinical guidelines help identify which children at risk of bacterial meningitis
...olleagues conducted a study to validate in a large population the clinical prediction rule, the Bacterial Meningitis Score, which classifies patients at very low risk of bacterial meningitis if they lack 5 criteria, which include certain CSF measurements and a history of seizure. The multicenter study was condu...Study examines risk of soft tissue sarcomas in hereditary retinoblastoma survivors
...retinoblastoma survivors compared with the general population and a 390-fold increase in cases of leiomyosarcomas. Only 20 percent of the soft tissue sarcomas were diagnosed within 10 years of the retinoblastoma diagnosis; 45 percent of the sarcomas arose 30 or more years after diagnosis. In addition, 18 of t...Tuberculosis risks for health workers in developing countries
...und to have latent TB. One third of the world's population is infected with Mycobacterium tuberculosis, the b...lso substantially higher than those in the general population of the same countries. In high-income countries, measures are in place to reduce the TB infectio...UCLA study finds a need for services that help homeless youth obtain health insurance
...th with a history of homelessness are a vulnerable population at high risk for negative health outcomes. The findings suggest that facilitating health insurance coverage for them may lead to increased use of outpatient care services, which may prevent costly emergency room services for conditions that could hav...