Mayo Clinic study finds heart transplant patients benefit from new approach to immunosuppression
... an anti-proliferative immunosuppression drug with potent anti-rejection properties. One study involving 78 heart transplant patients over four years found that gradually transitioning stable patients from calcineurin inhibitors to sirolimus showed consistent improvement of kidney function. There was no ...Green tea compound may be a therapy for people with rheumatoid arthritis
...ental Biology 2007 in Washington, D.C., looks at a potent anti-inflammatory compound derived from green tea....nd has the capability to block the activity of two potent molecules, IL-6 and cyclooxygenase-2 (COX-2), which also are actively involved in causing bone erosi...Green tea compound suppresses factors causing cartilage, bone destruction in arthritis
...G), an active principal of green tea extract, is a potent anti-inflammatory molecule, and also was able to i... the capability to block the activity of two other potent molecules, IL-6 and cyclooxygenase-2 (COX-2), actively involved in causing bone erosion in the RA jo...Commonly used drug offers promise for premature babies
...rgaard and Ballabh point out that ZD6474 is a very potent medication not likely to be given to pregnant women in the near future. Overall, the best way to prevent the problem, doctors say, is to do everything possible to allow a pregnant woman to carry a pregnancy for a full 40 weeks. So doctors put a gre...The hepatitis C link: Diagnose, treat, transplant
...uch as the lypophosphatidic acid receptor (LPA), a potent signaling molecule, were also over-expressed in HCV patients. "Early detection of liver cancer is crucial. For patients eligible for liver transplant, early detection is associated with excellent long term cancer survival," said Mary Maluccio, M....Human antibodies protect mice from avian flu
...Dr. Subbarao. They show that fully human mAbs with potent H5N1 influenza virus neutralizing ability can be rapidly generated from the blood of convalescent patients and that these mAbs work well to both treat H5N1 infection and prevent death from such infection in a mouse model. The authors plan to take the...Scripps Research awarded $17 million for adult stem cell use to treat eye diseases
...t it may be possible to use these cells to deliver potent anti-angiogenic molecules to the tumor and, thus, kill it." A major strength of the new grant is bringing together expertise from a variety of fields represented in different Scripps Research labs to address the use of stem cell therapy for treatin...Case study: cross-cultural bioethics training program helps fight African 'brain drain'
...e. For the first time, the case study reveals some potent lessons in what it takes to deliver a successful, cross-cultural ethics training program. We initially sought to increase the critical mass of African individuals professionally trained in ethics, said Nancy Kass, ScD, deputy director for public h...NIH scientists target future pandemic strains of H5N1 avian influenza
...ntibodies that target H5N1 were up to tenfold less potent against the mutants. Dr. Nabel and his colleagues used their knowledge of receptor specificity to create vaccines and isolate new antibodies that might be used therapeutically against human-adapted mutants. They vaccinated mice with the material f...