Metabolic side effects of antipsychotics are known, but rarely monitored
...s genetic make-up of their serotonin receptors can predict whether a patient will gain weight or not during treatment with clozapine." Another study being presented seeks to give physicians and patients information on which of the newer drugs are best for cognition. Impaired cognition problems with the abi...Certain weight control behaviors may precipitate obesity among adolescent girls
...ination of genetics and environmental factors that predict obesity. Interestingly, the weight-control behavio... foods, binge eating and lack of exercise did not predict the onset of obesity, possibly because people tend not to report these behaviors very accurately, no...Early stage breast-cancer rates are rising as incidence of invasive cases are leveling
...i said. "However, if we could develop new tools to predict which women with LCIS are more likely to develop invasive cancer we could better counsel them on what might be appropriate treatment options," he said. LCIS is characterized by precancerous changes in the cells that line the milk-producing lobules, o...Jefferson researchers find timing of post-epilepsy surgery seizures predicts outcome
... seizures. These results, if confirmed, "May help predict the long-term success of surgery and help the patient's peace of mind," he notes. "While seizures in the first few months indicate a worse prognosis, many patients still do well in the long run," says Dr. Sperling, noting that experiencing a seizure ...Cost-effectiveness of drugs may vary across borders
...tions in one country give little basis on which to predict cost-effectiveness across borders. Factors affecting the variations include demography and epidemiology of disease, difference in clinical practice patterns, and differences in relative prices cross-country. This variability is a particular concern ...One-meter waistline predicts high risk of diabetes and heart disease
...ferent body measurements and biological markers to predict insulin sensitivity. Their study involved 2,746 healthy male and female volunteers aged between 18-72 years with body mass indexes from 18-60 kg/m2 and waist circumferences from 65-150 cm. Height, weight, waist and hip circumference were measured and...Prostate cancer therapy - study suggests new molecular screening theory
...la, April 15th) -- Levels of the Smad7 protein may predict therapeutic response in patients with prostate can...nd other proteins in this molecular pathway, might predict the cell-killing ability of other cancer therapeutics and thus their effectiveness for treating indi...Northwestern's cancer genetics program finds gene variants that greatly increase breast cancer risk
...lly-occurring variants of the TGF-beta pathway may predict breast cancer risk. It is also the first study ass... finding is promising as it may eventually help us predict breast cancer risk in a large subset of the population. Indeed, breast cancer risk may be predicted...Rice, NC State win NAS/Keck Futures funding
...bility and hydrophobicity, which are often used to predict uptake and activity of traditional hydrocarbons but which have not been extended to fullerenes. They will also try to determine what properties correlate to cell uptake and what properties correlate to cellular activity. Barron and Monteiro-Riviere's...Measuring enzymes at end of cancer pathway predicts outcome of Tarceva, Taxol
...l growth factor receptor (EGFR), but that does not predict response to the targeted therapy in other forms of cancer, Ueno says. "We find here that as long as CDK2 is suppressed, the drug works, so developing an accurate test for CDK2 activity would be a boon for delivering individualized therapy to patients...Researchers develop 'genetic blueprint' to predict response to esophageal cancer treatments
...o use a comprehensive panel of genetic variants to predict how a patient with esophageal cancer will respond ...Center report that six different gene variants can predict an improved outcome in patients treated with two different chemotherapy drugs and/or with radiation ...New prognostic markers help identify risk of relapse
...ostic factors (low ANC and high MRD) were found to predict outcome by distinct mechanisms and to have independent prognostic significance. "These results are very promising," says A/Prof Marshall. "If ANC levels can complement MRD levels at the end of induction in predicting relapse as our study indicates, i...Tools for diagnosing heart attack could be inaccurate in some populations
...ictive Instrument (ACI-TIPI), which is designed to predict whether a patient is having a heart attack. Although ACI-TIPI itself is not widely used clinically, its elements form the basis of many other risk assessment tools. There is no single, definitive test to diagnose heart attacks, making it difficult to...Study reveals new data on how lyme disease is spread
... or absence of blood stream invasion impossible to predict with certainty based on clinical features alone. Younger patients and those with a prior history of Lyme disease were somewhat protected. Dr. Wormser and his colleagues concluded that, "The high rate, early onset, and prolonged duration of risk for b...Other highlights in the May 4 JNCI
...g new technologies that may improve our ability to predict or detect cervical neoplasia, we must not lose sight of the need to increase screening adherence," the authors write. "Even the most perfect screening method will not detect disease in a woman who has not participated in the prevention process." Cont...Long-term outcomes promising for patients with localized, low-grade prostate cancer
...onounced improvements in the ability of models to predict not only true stage but outcomes based on blood or...ar technologies. Indeed, one thing that is safe to predict right now is that in 20 years, commentators discussing on the natural history of prostate cancers di...Mayo Clinic first to use pharmacogenomics to treat inherited kidney disorder of children
...have used the finding to develop a genetic test to predict which patients are best suited for this treatment....n explanation for the varied response and a way to predict who will respond to vitamin B6 therapy. By studying 23 patients' genetic profiles and their response...Stroke drug still meets resistance from doctors wary of its risks
...d choose the best treatment. In fact, the authors predict that tPA use will increase as hospitals increasingly form stroke teams and write plans for what to do when a stroke patient comes through the emergency department door. Primary Stroke Centers are now recognized by the main hospital accreditation orga...New blood test for ovarian cancer screening
...falls within a certain warning area, the test will predict that she has cancer. In a test group of over 200 ovarian cancer patients and healthy women, the test showed 95 percent sensitivity (fraction correctly diagnosed with cancer) and 95 percent specificity (fraction correctly diagnosed as cancer-free). Ea...Untreated low-grade ductal carcinoma in situ poses long-term risk
...as ADH lesions pose only small malignancy risk and predict risk to both breasts rather than regional risk. With the advent of mammography, DCIS is now identified earlier and is the largest growing subset of breast cancers. Understanding the natural history of low-grade DCIS can provide insight into current a...