Institute of Medicine news: Review of HIVNET 012 study
...12 study, which showed that nevirapine effectively prevents many infants from contracting HIV from their infected mothers, are sound and reliable," said James Ware, chair of the committee that wrote the report, and professor of biostatistics, Harvard School of Public Health, Boston. "None of the shortcomings...Data show cyclosporine inhalation solution improves long-term survival in lung-transplant patients
...y presented at ISHLT last year indicated that CyIS prevents chronic rejection, the most common cause of death in lung-transplant recipients. These follow-up data indicate that the significant survival advantage of CyIS compared to placebo persists long-term," said Aldo Iacono, M.D., lead investigator of the s...Fifteen-year hunt uncovers gene behind 'pseudothalidomide' syndrome
...s. Although there's some evidence that thalidomide prevents blood vessel growth, it's not clear why. If the underlying biology is related somehow, then thalidomide might affect chromosomes and cell division like ESCO2 in Roberts syndrome, Jabs speculates. During normal cell division, every chromosome is copie...Rats with migraines provide Jefferson scientists insights to improved drug strategy
... with DHE at the beginning of the induced headache prevents the headache from progressing to the debilitating sensitization state. "Physicians have used intravenous DHE as a standard treatment for patients admitted to the hospital for their migraines," Dr. Oshinsky notes. "The data in this new study suggest...New treatment for hereditary breast cancer
...he damage. The new treatment uses a chemical that prevents PARP from repairing the DNA, making recombination essential. The breast cancer tumour cannot perform recombination and is therefore unable to replicate and create new cells. The tumour is then unable to grow and eventually dies. The beauty of this s...Melbourne researchers develop safer and more effective 'aspirin'
...rugs. The 'holy grail' in the field is a drug that prevents disease-causing clots whilst not increasing the risk of bleeding." Animal studies have shown that the drugs, developed by Dr Jackson and colleagues at the Department of Pharmacology at the University of Melbourne, Cerylid Biosciences and the Universi...Exclusive breastfeeding reduces risk of mother-to-child HIV transmission
... percent of all pediatric HIV infections, yet also prevents millions of child deaths every year by protecting infants from diarrhea and other infections. Finding ways to make breastfeeding safer for infants of HIV-infected mothers has been an urgent research priority. A study conducted by the Johns Hopkins Bl...No wisdom in routinely pulling wisdom teeth, study says
...es focused only on whether removal of wisdom teeth prevents crowding in the lower jaw within five years, and neither study revealed a significant benefit. "The conclusion drawn from [the larger] study was that the removal of impacted third molars to reduce or prevent late incisor crowding cannot be justified,...UT Southwestern researchers show new drug may help treat certain forms of leukemia
...L. The drug blocks signals within cancer cells and prevents a series of chemical reactions that cause the cells to grow and divide. Although Gleevec has been highly successful against CML, it is unknown whether the drug can permanently eradicate all leukemia cells with the specific aberrant enzyme found in CM...Routine procedure during childbirth provides no benefits, study review finds
...omy, Thorp added, is that performing an episiotomy prevents more serious injury to the mother. It had been thought that a deliberate incision would heal more quickly and with fewer complications than a spontaneous tear, and that a woman who has an episiotomy would be less likely to have pelvic floor problems,...An alternative to prevent UC-associated colon cancer
... Medicine at the U-M Medical School. "Surveillance prevents cancer by leading patients to have colectomies, the surgical removal of part or the entire colon, which can significantly decrease their quality of life," says Rubenstein, who also is a staff physician at the Veteran's Affairs Ann Arbor Healthcare Sy...Targeted cancer drug combined with low-dose chemotherapy shrinks tumors, slows ovarian cancer
...e of a new class of "anti-angiogenesis" drugs that prevents the growth of blood vessels that feed cancer tumors. The study, presented at the 41st annual meeting of the American Society of Clinical Oncology (ASCO) in Orlando, Florida, evaluated 29 patients with recurrent ovarian cancer after having undergone ...Study shows Erbitux may fight colorectal cancer after other therapies fail
... and poor prognosis, Lenz explains. Cetuximab also prevents DNA from being repaired, blocks metastasis and suppresses the formation of blood vessels to nourish the tumor, he adds. The most frequently reported side effects were skin rashes, weakness and nausea....Penn researchers find relief for gastrointestinal illnesses
...O) -- a condition such as Crohn's disease -- which prevents the body from absorbing enough nutrients from the small intestines; and pouchitis, an inflammation of an internal pouch created in patients who have had a section of colon removed. Both conditions are commonly treated with antibiotics. However, us...Patients at high risk of stroke may need to continue warfarin after heart rhythm is controlled
...HICAGO Treatment with warfarin, a medication that prevents blood clotting, may reduce the risk of stroke by more than two-thirds in patients with atrial fibrillation (AF), a condition which places them at high risk of stroke, according to a study in the May 23 issue of Archives of Internal Medicine, one of t...Tiny bundles seek and destroy breast cancer cells
...hat ceramide, a naturally occurring substance that prevents the growth of cells, can be administered through the blood stream to target and kill cancer cells. "Ceramide is the substance that accumulates in cancer tissues and helps to kill cancer cells when patients undergo chemotherapy and radiation," said M...Risk factors in contracting cancer of the endometrium
...d not be misinterpreted. Tobacco at a fertile age prevents endometrial cancer, apparently because it lowers oestrogen levels - the reason why women smokers are more prone to osteoporosis and early menopause. Moreover, it has to be taken into account that tobacco increases the possibilities of other types of ...Oral liquid hydroxyurea promising for long-term use in babies with sickle cell anemia
...port protein in fetal red blood cells. Because HbF prevents red blood cells from sickling, clinicians have used hydroxyurea for about a decade to reactivate HbF production in adults and older children with SCA. In addition, hydroxyurea reduces the severity of symptoms suffered by adolescents and adults with S...Should everyone over 50 be taking aspirin?
...rom it. Based on data for 55-59 year olds, aspirin prevents around two first heart attacks per 1000 population each year. However, this benefit does not outweigh the expected risk of a major gastrointestinal bleed at age 60 (1-2 per 1000 per year). "In my view, we should not contemplate an age threshold app......e of a new class of "anti-angiogenesis" drugs that prevents the growth of blood vessels that feed cancer tumors. PATIENTS WITH METABOLIC SYNDROME AND MODERATE LEVELS OF CORONARY CALCIUM FOUND TO HAVE A GREATER CHANCE OF HAVING BLOCKED ARTERIES, AS DETECTED ON A STRESS IMAGING TEST Researchers at Cedars-Sin...