Studies examine menopausal hormone therapy and risk of breast cancer recurrence
...itional evidence that use of combined estrogen and progestin is associated with an increased risk of breast cancer. However, they write, "the lack of direct evidence for the effects of estrogen alone from these two trials, especially in the context of divergent data on the effects of exogenous estrogen, emphas...Other highlights in the May 4 JNCI
...mal model. Medroxyprogesterone acetate (MPA) is a progestin that is used in Depo-Provera and has been tested as a treatment for advanced breast cancer. An earlier study found that MPA increases the expression of a metastasis suppressor gene called Nm23-H1 in estrogen and progesterone receptor-negative breast ...Annals of Internal Medicine tip sheet for May 17, 2005
...mmend against routine use of combined estrogen and progestin for the sole use of preventing chronic conditions. 3. Slightly Elevated Blood Sugar Levels Not Associated with New Heart Attacks, Study Finds An analysis of data on 2,763 postmenopausal women with established coronary heart disease finds that wome...Women report various symptoms after stopping hormone therapy
... the Women's Health Initiative (WHI) estrogen plus progestin (E + P) trial findings that the overall health ris...one [CEE + MPA] or placebo) when the estrogen plus progestin intervention (part of the WHI study) was stopped. Surveys were mailed 8 to 12 months after the stop...Long-term smoking is associated with up to 40 percent increased risk of breast cancer
... association in smokers who used both estrogen and progestin and not among women who used estrogen alone. We will follow up on this finding in future studies to see if it can be replicated." Another interesting and encouraging finding was that once a woman stops smoking, within about 10 years of quitting her...BRCA1 gene found to inhibit two sex hormones, not just one
...eplacement therapy that includes both estrogen and progestin (a synthetic form of progesterone) are at greater risk of developing breast cancer than women who use only estrogen replacement. The use of progesterone in the breast is tightly regulated and is primarily activated when growth in cells is needed, suc...Low-fat diet's benefits for women less than expected, Stanford researcher says
...ed that estrogen and a combination of estrogen and progestin increased risks in such diseases as stroke, blood clots and breast cancer among postmenopausal women. The third study on the effects of calcium and Vitamin D on bone fractures and colorectal cancer will be released later this month....Genes and environment interact to promote cancer
...drug, Valproic acid, potently boosted estrogen and progestin activity inside cells. The elevated hormone levels are likely responsible for the reproductive failures and breast cancers seen among women exposed to these chemicals, said Duke pharmacologist Donald McDonnell, Ph.D. "Our study demonstrates that thes...Hormone use linked to increased breast cancer risk among black women
...was slightly higher for women taking estrogen with progestin than for those taking progestin alone. The association between hormone use and breast cancer was strongest for women who were lean,...Postmenopausal hormone therapy appears to increase risk of blood clots in veins
...ne WHI trial examined the effects of estrogen plus progestin and found that this combination of hormones appear... was lower than that associated with estrogen plus progestin in the other WHI trial. "Our data suggest that although the absolute incidence is relatively low, th...WHI updated analysis: No increased risk of breast cancer with estrogen-alone
...ing combined hormones may be due to the effects of progestin when it is combined with estrogen....No link between estrogen-only therapy, breast cancer in postmenopausal women
...e of hormone therapy - which combined estrogen and progestin - did result in a higher risk of breast cancer among postmenopausal women. Marcia Stefanick, PhD, a Stanford University School of Medicine researcher who oversaw the latest WHI findings, said she hopes the results provide some clarity. "The clinical ...Use of estrogen by postmenopausal women does not increase risk of breast cancer
...ghly suggestive of malignancy in the estrogen plus progestin (E + P) trial. Initiation of CEE alone in women after hysterectomy should continue to be based on careful consideration of potential risks and benefits for a given individual," the authors write....Menopausal women don't get enough guidance on treatment options, Stanford survey shows
...ither estrogen nor the combination of estrogen and progestin helped prevent heart disease. Instead, although both forms of hormone therapy offered some benefits in easing menopausal symptoms, they both posed substantial health risks. Despite these risks, hormone therapy is still considered the most effective a...Estrogen plus testosterone therapy may increase risk of breast cancer in postmenopausal women
... use (15 percent) and current use of estrogen plus progestin (58 percent). When the researchers considered onl...antial evidence implicating combined estrogen plus progestin therapy in breast cancer and the results of the present study regarding estrogen plus testosterone t...Hormone-replacement therapy hurts hearing, study finds
...men not taking HRT. On average, women who received progestin had the hearing of women five to 10 years older. ...h in Otolaryngology. The new results also identify progestin as the component of HRT doing possible damage. "Whether a woman goes on HRT is certainly her decis...Breast discomfort during hormone therapy may indicate increased risk for breast cancer
...own that postmenopausal women taking estrogen plus progestin in hormone replacement therapy experience both increased breast density and breast discomfort. The researchers sought to determine whether the discomfort was a signal for increased density. Using data from women enrolled in the Postmenopausal Estroge...Hormonal contraception does not appear to increase HIV risk
...etate (DMPA), an injected contraceptive containing progestin only. Numerous studies have considered the issue of whether contraceptives might increase a womans risk of becoming infected with HIV. The results of these studies, however, are inconclusive. The current study was commissioned by NIHs National In...Decline in breast cancer cases likely linked to reduced use of hormone replacement
...." HRT provides both estrogen and sometimes also progestin hormones to women who are postmenopausal. The ongo...in July, 2002 when the combination of estrogen and progestin was found to significantly increase the risk of developing invasive breast cancer. Ravdin said ab......eated women and women on estrogen or estrogen plus progestin determine risk of hip fracture and breast cancer. ...ers by whether or not the estrogen is opposed by a progestin and if how a woman metabolizes estrogen on hormone therapy relates to the risk of hip fracture. "...