DNA vaccine against multiple sclerosis appears safe, potentially beneficial
...tic periods and periods of remission] or secondary progressive MS [when symptoms progressively worsen, but there still may be periods of remission]. After one, three, five and nine weeks, participants received intramuscular injections of placebo or BHT-3009 (in doses of .5 milligrams, 1.5 milligrams or 3 milligr...Smoking may strongly increase long-term risk of eye disease
...nals. Age-related macular degeneration (AMD) [a progressive eye disease that affects the central portion of the retina] is the leading cause of blindness in the Western world, according to background information in the article. In addition to smoking, AMD is postulated to share other risk factors with cardiov...Fluctuating eye pressure associated with visual field deterioration in glaucoma patients
...ean [average] and peak IOP does not always prevent progressive visual field deterioration. Samin Hong, M.D., an...er fluctuation in IOP. The number of patients with progressive visual field loss was significantly larger in the group with more fluctuation. Our results suggest...1 of 2 pediatric kidney disease research centers in world established
...or thousands of children with genetic, acquired or progressive kidney disease. This new Center of Excellence des... the resources to understand and effectively treat progressive kidney diseases in children. It also will permit us to attract and mentor a new group of physicians ...Investigating the causes of Parkinson's disease
...ure to specialise in Parkinsons. Parkinsons is a progressive neurological condition caused by the death of nerve cells in the brain that produce the chemical dopamine, which is responsible for movement. The condition affects movements such as walking, talking, and writing. Its three main symptoms are tremor, m...UK scientists set their sights on cure for AMD
...hese cells, and so failure of these cells leads to progressive loss of vision. In addition, the disease often provokes a scarring process at the back of the eye leading to the formation of new blood vessels within the retina which subsequently leak fluid resulting in exudative or so called wet AMD. The London...Benefits of trastuzumab are lasting, reducing both HER2 + breast cancer deaths and recurrence
... in the trastuzumab treatment group have developed progressive disease, a second primary cancer or contralateral breast cancer (cancer in the other breast), compared with 243 patients in the chemotherapy group. In one of the trials (NCCTG-N9831), Dr. Perez reports that the risk of weakened heart muscle was gr...Drug shows activity against brain metastases
...d on tumor volume reductions in some patients with progressive HER2-positive disease of the central nervous system after being treated with Herceptin and radiation, the researchers said. ...Mouse model points to possible new strategy for treating rare muscle disease, kidney disorders
...mptoms that emerge in adulthood and lead to slowly progressive muscle weakness. Most patients develop symptoms while in their early 20s and become wheelchair-bound by the time they reach 40, as their arm, hand, leg and core muscles progressively weaken. It is caused by a mutation in the GNE gene, which codes for...Human stem cell treatment restores motor function in paralyzed rats
...lls directly into the spinal cord we can achieve a progressive recovery of motor function, said Marsala. This co...on was evaluated in seven-day intervals, showing a progressive recovery of ambulatory functions in the rats that received stem cells. Three of the nine rats inje...Scripps Research awarded $17 million for adult stem cell use to treat eye diseases
...enerative diseases such as retinitis pigmentosa, a progressive eye disease affecting the rods and cones in the retina, and age-related macular degeneration, a condition that gradually destroys sharp, central vision and is the leading cause of vision loss in Americans age 60 and older. Glaucoma, in which increase...Personality changes may help detect form of dementia
...tient and family members more time to plan for the progressive decline." Galvin said more detailed personality tests are not often used in most office settings because of time and lack of training. "Our results show incorporating a brief, simple inventory of personality traits may help improve the detection of...ACE inhibitors help preserve kidney function in IgA nephropathy
...The finding that ACE inhibitors reduce the risk of progressive kidney disease in young patients with early-stage ...duce the number of patients who eventually develop progressive kidney disease requiring dialysis. Dr. Coppo concludes, "It is of interest that most of the patients...Testosterone may help men with multiple sclerosis
... JAMA/Archives journals. Multiple sclerosis is a progressive disease involving the immune and central nervous systems. MS and many other autoimmune diseases (in which the body attacks its own systems or tissues) are less common in men than in women, according to background information in the article. This is e...Mediterranean diet halves risk of progressive lung disease
...editerranean diet halves the chances of developing progressive inflammatory lung disease (COPD), reveals a large ...pulmonary disease) is an umbrella term for chronic progressive lung disease, such as emphysema and bronchitis. It is expected to become the third leading cause of ...SCAI'S Hildner Lecture traces progress through 30 years of interventional cardiology
...ge is that over the last 30 years, there have been progressive improvements in the success, safety, and durability of PCI as new technologies have been launched," Dr. Baim said. "But as each innovation solved a serious prior problem, it sometimes introduced a rare new adverse event that needed its own solution."...Breakdown of myelin implicated in Alzheimer's, UCLA research shows
...artzokis said. "That's what we think underlies the progressive spread of the neuritic plaques from the late-myelinating regions toward the earlier-myelinating regions." Bartzokis noted that a similar progression has been described clinically of the cognitive, functional and neurologic declines that accompany ...New therapeutic targets for neurodegenerative diseases
...eutical medicines, in order to stop the process of progressive deterioration, substances that favour the survival of the neurones and oligodendrocytes are also sought; substances such as, for example, antioxidants, given that, in many of the neurodegenerative illnesses the cells die because oxidative stress is p...First clinical trial of gene therapy for childhood blindness
...nherited retinal degeneration. This disease causes progressive deterioration in vision, due to an abnormality in a particular gene called RPE65. This defect prevents normal function of the retina, the light-sensitive layer of cells at the back of the eye. This results in severely impaired vision from a very youn...Studies suggest investigational agent reduces disease activity in MS
...th fatal infusion reactions, tumor lysis syndrome, progressive multifocal leukoencephalopathy, renal toxicity, and other adverse effects. ...