Penn study finds pro-death proteins required to regulate healthy immune function
...ll death are also necessary for the maturation and proliferation of immune cells. Activation of T-cell receptors on... stimulated on mutant cells lacking both proteins, proliferation was severely reduced relative to normal cells. Closer investigation showed that the amount and rate ...Stanford researchers find culprit in aging muscles that heal poorly
...ditionally thought to help promote maintenance and proliferation of stem cells in many tissues. But in this instance, Wnt appears to block proper communication. "That was a total surprise," said Thomas Rando, MD, PhD, associate professor of neurology and neurological sciences. "We had no idea that the Wnt signal...Targeted, oral agent Enzastaurin shows favorable results
... in-cluded: testing enzastaurin on cell signaling, proliferation and apoptosis in breast cancer, testing in Phase I/II with radiation combination therapy for first-line treatment of glioblastoma multiforme, a pre-clinical study on ovarian chemo-resistant cancer cell lines, testing for growth suppression in pancrea...Scripps Research awarded $17 million for adult stem cell use to treat eye diseases
...r enhance neuroprotection or to interfere with the proliferation of blood vessels. If successful, this approach could have broad treatment implications not only for eye disease, but also for some types of tumors. "We know that these particular stem cells like to target certain connective tissue cells of the centra...Innovative device to treat brain cancer shows promise in early studies
... this distinction enables the device to stop local proliferation and metastasis of cancer, which would explain the efficacy observed in these early findings," said Dr. Elion Kirson lead author and Vice President of Research and Development, NovoCure. "Based on our preliminary research, we believe that there is a h...Role of TRPM8 in the development of prostate cancer
...lls. Disrupted or dysregulated differentiation and proliferation are major causes of cancer. In a study appearing online on May 17 in advance of publication in the June print issue of the Journal of Clinical Investigation, Natalia Prevarskaya from Universit des Sciences et Technologies de Lille, France, show that ...JCI table of contents -- May 17, 2007
...lls. Disrupted or dysregulated differentiation and proliferation are major causes of cancer. In a study appearing online on May 17 in advance of publication in the June print issue of the Journal of Clinical Investigation, Natalia Prevarskaya from Universit des Sciences et Technologies de Lille, France, show that ...JCI table of contents: May 10, 2007
... a negative regulator of Ras- and Raf-induced cell proliferation and as an important mediator of the antiinflammatory effects of glucocorticoids. TITLE: GILZ mediates the antiproliferative activity of glucocorticoids by negative regulation of Ras signaling AUTHOR CONTACT: Carlo Riccardi University of Perugia...Hepatitis C increases risk of non-Hodgkin lymphoma
...proliferative precursor diseases (referring to the proliferation of the bone marrow cells that give rise to lymphoid cells), and thyroid cancer. There were 1,359 cases of non-Hodgkin lymphoma, 165 cases of Waldenstrm macroglobulinemia (a low grade lymphoma), 551 cases of cryoglobulinemia and 320 cases of thyroid...Diet and lifestyle -- In the cancer fight, eating well is the best revenge
... of these constituents to inhibit cell cycle, cell proliferation and oxidative stress, and to induce detoxification enzymes and apoptosis," Nthlings said. Polyp characteristics, diet, lifestyle factors and high-risk colorectal adenoma recurrence in the polyp prevention trial: Abstract 861 Experts agree tha...First step in developing heart hormone-based pill to control high blood pressure
...important for heart health, such as resisting cell proliferation and promoting dilation of blood vessels without causing low blood pressure. However, CNP had no effect on increasing kidney filtration. But another peptide, called D-type natriuretic peptide (DNP), did. The Mayo Clinic solution was to synthesize a hy...Blueberries contain chemical that may help prevent colon cancer
...iates say. Pterostilbene also reduced colonic cell proliferation and inhibited certain genes involved in inflammation, both of which are considered colon cancer risk factors, the researchers say. Although researchers still do not know the exact cause of colon cancer, the disease has been linked to a high intake ...On a diet? You'll spend more on impulse purchases
...ies for impulse purchasing have increased with the proliferation of ATMs, shopping on the Internet, and shop-at-home television programs. Instead of gauging desire for things, they are the first to measure actual spending patterns after the exertion of self-control, expanding the literature to include the impulse ...Aspirin reduces esophageal-cancer risk in people with most-aggressive form of Barrett's esophagus
... development. NSAIDs are also believed to decrease proliferation of cells and decrease the growth of blood vessels that supply blood to tumors, Reid said. The annual incidence of esophageal cancer among Barretts esophagus patients is about1 percent most patients never get the cancer. However, the outlook is grim ...Grants from leading eye research foundation surpass $9M in 2006
...ng mystery and a finding that may help prevent the proliferation of blood vessels in some blinding eye disorders and cancers. "RPB's mission is broad in terms of the spectrum of eye disease, but our strategy has always been targeted at those researchers and research communities most likely to yield crucial insig...Nano world off the radar for most
...res are the rage in engineering schools. While the proliferation of nano research may signal a mini revolution, outside the realms of business and science, this insurgency may be no more than a whisper, according to an international team of researchers. "In the last 15 years we have continuously been exposed to a...JRRD releases single-topic issue focused on vision rehabilitation
Migration and proliferation of retinal pigment epithelium on extracellular matrix ligands, pg. 713 Our goal is to develop a surgical treatment that will improve vision for patients with agerelated macular degeneration (AMD). AMD is the most common cause of blindness among peop...Mistletoe is not an anti-cancer drug, say doctors
...ven suggest that mistletoe extract may enhance the proliferation of some cancers. So the claim that mistletoe injections have no serious risks is misleading, argues Ernst. Mistletoe has been tested extensively as a treatment for cancer, but the most reliable trials fail to show benefit, and some reports show c...Stem cell activity deciphered in the aging brain
...enriching environment, that are known to stimulate proliferation of stem cells....Options improving for patients with acromegaly and gigantism, says endocrinology expert
...ess the secretion of growth hormone, interrupt the proliferation of somatotroph cells, and block the synthesis of IGF-I. High cost and temporary, unpleasant side effects continue to be factors, and the medications are not effective in or tolerated by all patients, but new alternatives are currently undergoing clin...