Test accurately predicts aggressiveness of breast cancer
...that the molecule Ki67 is a good indicator of cell proliferation rate, and the marker is already used to define the...us, and other parameters. "We found that high cell proliferation rate, measured as Ki67 levels, correlates with larger tumor size, axillary nodal involvement, higher...Exposure to carcinogenic crop toxin lowered by simple intervention
..., humidity, insect and rodent damage can result in proliferation and spread of fungal spores. Chris Wild (University of Leeds, UK) and colleagues introduced a simple packaged intervention to improve storage of groundnuts among farmers in a rural area of Guinea, West Africa. Farms from twenty villages were includ...New technique appears to stop abnormal blood vessel growth
... researchers have reduced destructive blood vessel proliferation by up to two-thirds. Findings are published in the May issue of Investigative Ophthalmology & Visual Science."We have a promising new preclinical approach to treat conditions that involve blood vessel formation," says Dr. Ambati. These include cornea...Researchers prevent post-traumatic brain damage
... required for glial cells to grow and divide. This proliferation produces a "glial scar" that can limit recovery. The same process also activates a type of glial cell, called microglia, that are involved in brain inflammation after injury. At the same time, the cell cycle in neurons is activated, but because these...Dermatologists use immunotherapy to treat warts
... information provided in the article. Because wart proliferation is controlled by the immune system, various methods have been tried to stimulate an immune response to the human papillomavirus (HPV), the cause of skin warts. Previous studies have shown that injecting a wart with an antigen preparation of mumps, Ca...Blocking the Odc gene is effective in preventing cancers
...et of certain cancers in people by reining in cell proliferation so there's less opportunity for a second, cancer-triggering mutation to occur." Cleveland is senior author of a report on this work that appears in the May issue of Cancer Cell. Myc has many targets in the cell, a fact that makes it difficult to dete...Molecular change occurring during brain tumor progression also evident in breast cancer
...fold for cell attachment, regulates cell behavior, proliferation and migration. The laminin molecule is composed of... The molecular mechanisms that contribute to tumor proliferation may prove to be targets for therapeutic intervention." "The importance of the present paper is that ...Prevalence of concussion effects linked to 'pot of gold' lawsuits, researcher says
...hard C.W. Hall of the University of Florida says a proliferation of lawsuits driven by claims of postconcussional syndrome means more physicians are being asked to make high-stakes diagnoses -- often for patients who are tangled financially and psychologically in litigation. In the new review -- which appears in t...Kidney donation program may provide more matches for previously incompatible recipients and donors
... and algorithms is absolutely crucial to the smart proliferation of KPD in the United States and the prevention of a haphazard system that diminishes the impact of this promising approach to the organ shortage," the researchers write. "We believe that KPD should be the preferred treatment for patients who have inc...Angiogenesis factor may help tumors prepare the way for spread to lymph nodes
...t the MGH and elsewhere found that it also induced proliferation of lymphatic tissue and vessels in laboratory and animal models. As a result, the MGH team decided to investigate its possible role in tumor-associated lymphangiogenesis. Research fellow Satoshi Hirakawa, MD, PhD, the study's first author developed a...