UCLA Nobel Laureate honored with membership in the American Philosophical Society
...rly Sills. The American Philosophical Society promotes knowledge through scholarly research, professional meetings, publications, library resources and community outreach. Currently, there are 900 members. Ignarros groundbreaking discovery of the importance of nitric oxide in cardiovascular health se...Steps needed to reduce smoking in the US
...n sell tobacco products and limit how the industry promotes its products. The committee acknowledged that its recommendations to impose greater restrictions on tobacco advertising may not survive a challenge on First Amendment grounds. However, the report argues that restricting companies' ability to enco...New insights into chronic inflammation and atherosclerosis
.... The vascular inflammation might be a factor that promotes atherosclerosis and the formation of aneurysms. Aortic samples were obtained during CABG surgery, performed at two cardiac centers in Norway, from 66 patients with inflammatory rheumatic disease and 51 control patients. The inflammatory rheu...Brain inflammation may be friend, not foe, for Alzheimer's patients
...flammation. IL-1 beta, a signaling molecule that promotes brain inflammation, was one of the first molecules that scientists found in higher levels in the brains of people with Alzheimers disease compared to healthy people. Its recognized as a critical player in bringing about much of the brain damage that ...Brain-boosting pill alleviates post-chemotherapy fogginess
...Originally licensed to treat narcolepsy, modafinil promotes wakefulness and seems to boost brainpower without causing the jittery, restless feelings induced by amphetamines. Modafinil is part of a class of drugs called eugeroics, which stimulate the brain only when it is required. The effects of modafinil dis...Study says normal but out-of-control enzyme may be culprit that signals some cells to become cancer
...this study, we provided evidence showing that TOPK promotes transformation [of normal cells to cancerous ones] in colorectal carcinoma. The story begins with the frequent observation by researchers that members of this enzyme network are overactive in the cells of several human cancers. The function of all ...New research finds high prevalence of smoking among physicians in China
...n that targets physicians and medical students and promotes smoke-free hospitals. ...Penn researchers discover novel pathway for increasing 'good' cholesterol
...Research Assistant Professor of Pharmacology. This promotes an increased level of HDL-C in the blood. We showed that mice engineered to express high levels of PCSK5A had 50 percent higher HDL-C than control mice, says senior author Daniel J. Rader, MD, the Cooper/McLure Professor of Medicine and Associate ...Pathway links inflammation, angiogenesis and breast cancer
...gether help NF"B escape into the nucleus, where it promotes cell growth and blocks programmed cell death. IKKa then works separately in the nucleus and IKK in the cytosol to induce cancer through separate pathways....New cause of tamoxifen resistance in breast cancer cells discovered at Lombardi
...esearchers believe that the overexpression of XBP1 promotes cell survival by affecting the activity of the intrinsic apoptosis pathway. XBP1 may give us a much-needed clue for better predicting response to anti-estrogen therapies like Tamoxifen, explained Clarke. The presence of the activated protein at hi...Grandparents, older adults encouraged to seek help for a sleep disorder
...oduce and secrete less melatonin, the hormone that promotes sleep. They may also be more sensitive to changes in their environment, such as noise, and this may cause them to awaken. Further, older adults may also have other medical and psychiatric problems that can affect their sleep, says Dr. Krainson, add...