Smoking may strongly increase long-term risk of eye disease
...ary, the findings from this large population-based prospective study add evidence to a possible causal relationship between smoking and the long-term risk of late, but not early, AMD, the authors conclude. This supports speculation that AMD is a condition with multiple etiologic factors, and such joint effects c...Reanalysis of controversial meta-analysis says writing off rosiglitazone may be premature
...t Cedars-Sinai Medical Center,concludes "that only prospective clinical trials designed for the specific purpose of establishing the cardiovascular benefit or risk of rosiglitazone will resolve the controversy about its safety." In an Annals of Internal Medicine article, cardiologists George Diamond, M.D., and...Annals of Internal Medicine tip sheet for Aug. 7, 2007, issue
...that the risk controversy will only be solved with prospective clinical trials designed for the specific purpose of establishing the cardiovascular benefit or risk of rosiglitazone. (This Perspective piece is published early online by Annals of Internal Medicine at www.annals.org. Authors appeared before the F...Takeda responds to the FDA advisory committee recommendation
...is consistent: Short- and long-term studies, both prospective and observational, studies in both humans and animals, all have shown no evidence that ACTOS is associated with an increased risk of heart attack or stroke, said Mehmood Khan, M.D., TGRD president. Critical in this body of data is the PROactive (PROs...Patients with soft tissue sarcomas should be treated at high volume centers
...cases. They used the Florida cancer data system, a prospective database of all cancer cases in the state of Florida since 1981, to identify all records of soft tissue sarcomas up to 2001. A total of 6259 cases were extracted and, after duplicates were removed, the researchers arrived at a total of 5564 unique ca...Split the difference: Pill-splitting study looks at cost-saving step that could be used by millions
...impact on cholesterol levels. It is also the first prospective randomized controlled trial of pill-splitting, and the first to look at the impact of out-of-pocket costs on patients willingness to take the time to split pills. The study is published in the June issue of the American Journal of Managed Care by a...Simple test predicts 6-year risk of dementia
... Cardiovascular Health Cognition Study, a national prospective study sponsored by the National Heart, Lung, and Blood Institute (NHLBI). At the beginning of the study, none of the subjects were demented. Their mean age was 76. Fifty-nine percent were women and 15 percent were African-American. By the end of t...Drinking 4 or more cups of coffee a day may help prevent gout
...vard School of Public Health in Boston conducted a prospective study on 45,869 men over age 40 with no history of...ric acid levels among patients with existing gout, prospective studies of these populations would be valuable."...Study reveals aspirin's colorectal cancer prevention mechanism
..., the research team compiled data from two ongoing prospective research studies the Nurses Health Study (NHS) and the Health Professionals Follow-Up Study (HPFS). Both studies gather comprehensive health information on their participants every two years, which is analyzed for associations between factors such ...Efficacy and safety of Aripiprazole as adjunctive therapy in major depressive disorder
...hase, adults in this study underwent an eight-week prospective treatment phase with one ADT plus single-blind pla... was the mean change from baseline the end of the prospective treatment phase to the end of the randomized treatment phase in a standard measure called the MADRS...New prevention, treatment methods for patients with painful bowel inflammation
...or of this study. "However, data from this large, prospective cohort suggest that these foods do not increase the risk of diverticular complications. In fact, frequent popcorn and nut consumption were associated with a decreased risk of diverticulitis." Dr. Strate will present this study on Tuesday, May 22, ...Some vitamin supplements don't protect against lung cancer
...from the supplements, is one of the most detailed, prospective observational studies to look at the effect of vitamin supplements instead of vitamins from foods on lung cancer risk. People are spending billions of dollars on supplements, and there is a general sense in the population that they prevent cancer, ...Erectile dysfunction -- the canary in the mineshaft?
...and cardiovascular disease (CVD) in a large-cohort prospective analysis of 4,747 patients with a history of nephrolithiasis. CVD was defined as myocardial infarction, angina, need for coronary artery bypass graft and ischemic or hemorrhagic stroke. Risk of CVD in men with a history of nephrolithiasis was 1.15;...Could statins be a new option for hepatitis C patients?
...s and inaccuracies and should be only used to plan prospective trials. "It is important for statins to be studied prospectively for their effect on hepatitis C," says Ted Bader, M.D., of University of Oklahoma in Oklahoma City, Okla., and lead author of this study. "Further study may contribute to developin...Experts debate role of stenting, bypass surgery in left main coronary artery disease
...laque build-up within five years of surgery. "In a prospective trial with hard endpoints of death and heart attack, I think we might find that drug-eluting stents stand up well to bypass surgery in left main diseaseand if you could have a less invasive therapy, why wouldnt you choose that"" Drs. Mack and Mehra...Magnesium loss in patients given monoclonal antibodies
...validation of The Lancet Oncology data in a larger prospective study could help in the development of a model that accurately predicts those who are most at risk of severe hypomagnesaemia and candidates for monitoring and early intervention. In addition, Fakih proposes that intermittent treatment schedules could...Free weight training gets workers with rotator cuff injuries back on the job
...researchers now hope to test the model in a larger prospective trial of workers at varying levels of injury in order to demonstrate increased outcome efficacy with a standardized prescription and concurrently measure cost-benefit to the worker's compensation system....Eating cured meats frequently can lead to lower lung function and potential COPD
...tary nitrite intake warrants further evaluation in prospective longitudinal studies as a novel risk factor for COPD. ...Diet and lifestyle -- In the cancer fight, eating well is the best revenge
... and head and neck cancer in a large United States prospective cohort study: Abstract 849 A new study among AA...ers from the National Cancer Institute. A large prospective study of 500,000 men and women aged 50 and older has found that those who ate more fruit and vegetab...Study finds lack of health insurance may be associated with increased rates of stroke
...ment of myocardial infarction than in stroke. The prospective study of 15,792 participants in the Atherosclerosis Risk in Communities database also found that those who reported being uninsured at leas once were more often female and non-white with lower education levels and family incomes. People with insuranc...