Predicting cardiovascular problems in liver transplant patients
...lant populations. Appleton, et al., suggest future prospective studies that add newer reported risk factors to those previously established, including serum high sensitivity C-reactive protein, fibrinogen, homocysteine, lipoprotein and apolipoproteins A1 and B....The critical role of the meniscus in osteoarthritis of the knee
...otes. "Our study points to the need for critical, prospective evaluation of these new therapeutic options."...Obesity may affect response to asthma medications
...t material from previous trials. I'd like to see a prospective study in which lean patients and heavy patients are enrolled at the outset, and you compare both types of medications in both groups," Peters-Golden says. If verified by other studies, this insight may help physicians to better tailor medication regi...Large prospective study examines colon cancer risk in women
A prospective cohort study of 31,783 American women has found no...niversity of California-San Francisco, conducted a prospective study of a large cohort of post-menopausal women in the United States. Using the Breast Cancer Detec...New, expensive, widely-used drugs continue to cause liver problems, says Jefferson liver specialist
..."adaptation." The authors suggest that "only large prospective trials" will provide the missing information on the causes behind drug-related liver toxicity. Dr. Navarro notes that an ongoing National Institutes of Health-supported study at five medical centers looks at drug-induced liver disease by collecting D...Dutch study finds four in 10 heart attacks go unrecognised
...e men and women involved in the Rotterdam Study, a prospective population study investigating chronic disabling diseases. A total of 5,148 participants[2] with no evidence of prevalent myocardial infarction (MI) were enrolled from 1990-93. They underwent a baseline ECG and examination. Data from clinically recog...Radiologic signs more than double sensitivity of MRIs
... Using these four radiologic 'signs' increased the prospective characterization and sensitivity for the detection of radial tears from 37% to 89%," said Dr. Harper. "We feel that by using the four signs, most radiologists who interpret knee MRIs should have a high degree of success of prospectively identifying r...Course of bipolar disorder in youths described for the first time
...ients with bipolar disorder to date, and the first prospective naturalistic study of children and adolescents with bipolar spectrum disorders....Preventive treatment helps avoid Hepatitis B relapse during chemotherapy
...Catholic University of Korea in Seoul, conducted a prospective randomized study on pretreating HCC patients undergoing chemotherapy with lamivudine between January 2004 and February 2005. The study involved 36 patients with HCC who were given the drug while undergoing transarterial chemo-lipiodolization (TACL) c...Computer systems assisting orthopaedic surgeons
...ier, "between focused retrospective and systematic prospective research. Surgeons using these tools in a prospective approach can be more productive in their research, and draw conclusions for a given patient."...Point-of-care test proves more effective for recurrent bladder cancer than conventional lab test
...668 patients with a history of bladder cancer in a prospective study to evaluate the effectiveness of the NMP22 assay for detecting recurrences of the disease. Each patient provided a urine sample, which was tested for the presence of the NMP22 protein using the tumor marker assay and urine cytology. Bladder exa...Annals of Internal Medicine tip sheet for Jan. 17, 2006
...r Dementia by 30% to 40%, New Study Finds A large prospective study -- perhaps the most definitive yet of the relationship between exercise and dementia -- found that older adults who exercised at least three times per week were less likely to develop dementia than those who were less active (Article, p. 73). T...Cyclosporine inhibits hepatitis C virus in vitro
...nvites further investigation, the authors write. A prospective randomized comparative trial between cyclosporine and TAC should further evaluate their observations. "Due to the accelerated rate of disease progression and graft failure after liver transplantation in HCV patients," the authors conclude, "it will b...Reduced brain volume may predict dementia in healthy elderly people
...t develop dementia, even after six years. Further prospective population studies are therefore required to find additional biomarkers, including other brain imaging parameters, that alone or in combination with clinical and genetic characteristics can help separate those who are at risk for developing dementia ...Having sibling with cardiovascular disease associated with higher CVD risk
...a sibling with CVD. "Using validated events and a prospective design, our study substantially extends the knowledge base regarding the importance of sibling CVD. We observed that sibling CVD confers increased risks of CVD events above and beyond traditional risk factors and parental premature CVD. Thus, sibling...Monumental measurement of mortality
The world's largest prospective study on mortality, in which a staff of a thousand are monitoring 14 million people in 2.4 million representative households, is currently underway in India. As described in the open access journal PLoS Medicine, the study will ascertain the causes o...Smoking associated with severity of psoriasis
... series of patients with psoriasis enrolled in the prospective Utah Psoriasis Initiative (UPI) was compared with three population databases: the Behavioral Risk Factor Surveillance System of the Utah population, the 1998 patient-member survey from the National Psoriasis Foundation, and 500 adult patients who at...Blood test can accurately diagnose heart failure in patients with kidney dysfunction
...tic value of NT-proBNP, the analysis evaluated the prospective value of NT-proBNP testing for predicting death within 60 days. "In fact, NT-proBNP measurement was an even stronger predictor of death in breathless patients with significant renal insufficiency, emphasizing the fact that the marker is likely detec...Insulin levels and resistance linked to risk of pancreatic cancer
...sed on the findings from several retrospective and prospective observational studies, type 2 diabetes mellitus and glucose intolerance are fairly consistent, albeit somewhat controversial, risk factors for pancreatic cancer, according to background information in the article. This is because it has been unresolv...High intake of dietary fiber not associated with reduced risk of colorectal cancer
...ber intake and risk of colorectal cancer. But most prospective cohort studies have found no association between d...tal cancer by reanalyzing the primary data from 13 prospective cohort studies (Pooling Project of Prospective Studies of Diet and Cancer). The pooled analysis incl...