JCI table of contents: May 1, 2006
...ic T cells to respond to TGF-beta1 is critical for protection against the autoimmune response. These animals represent an important experimental tool for the study of immune-mediated diabetes. In an accompanying commentary, Dirk Homann and George Eisenbarth from the University of Colorado, Denver, discuss the c...Annals of Internal Medicine tip sheet for May 2, 2006
...perhaps duplicitous family requests, or what legal protection is provided for on-the-spot decisions....Boost to health and medical research funding visionary
...port for education and vocational training, strong protection for intellectual property, and the maintenance of an operating environment conducive to encouraging investment by the local and international biopharmaceutical industry," Mr Schneemann said. The Grant Review quotes Access Economics' estimate of consu...Vaccine given post-exposure protects monkeys against deadly Marburg virus
...nes might be beneficial. ARTICLE: "Postexposure protection against Marburg haemorrhagic fever with recombinant vesicular stomatitis virus vectors in non-human primates: an efficacy assessment," by KM Daddario-DiCaprio et al. The Lancet DOI: 10.1016/S0140-6736(06)68546-2 (2006). This study was conducted by sc...Vaccine could be effective after exposure to Marburg virus
...D, one of the study authors, states: "Postexposure protection against MARV [Marburg virus] in non-human primates provides a paradigm for the treatment of MARV haemorrhagic fever. Indeed, these data suggest that rVSV-based [Recombinant Vesicular Stomatitis Virus] filoviral vaccines might not only have potential ...Vulnerability to measles among nursery school children risen sharply
...pected to reach the levels required for population protection among young schoolchildren, say the authors....Locked door psychiatric units have more disadvantages than advantages say staff
... with secure and efficient care by 73 per cent and protection against the outside world by 68 per cent" says lead author Kristina Haglund. "We know where the patients are" commented one member of staff, while another said that "it gives patients a sense of security when the ward is locked." Another said that fa...Chemical guidance of T cells leads to immunologic memory and long-term immunity
... providing, together with antibodies, long-lasting protection following vaccinations," says NIAID Director Anthony S. Fauci, M.D. The body contains hundreds of millions of CD8+ T cells, but only a tiny fraction of them become activated during an infection. These are selected because each CD8+ T cell carries a u...Massive German floods monitored from space
...d data sources. The federal departments for flood protection and water management of the German states of Saxony, Saxony-Anhalt, Brandenburg and Lower Saxony, along with the city of Dresden's Department for Environment, used these maps. The police department of Potsdam also used the information to coordinate t...Europe slow to add infant pneumococcal vaccine to national programmes despite strong US results
...their risk and also provides added indirect "herd" protection for other unvaccinated members of the community. C...rall cases of childhood IPD may be prevented. Herd protection cannot be achieved without broad vaccine coverage" says lead author Dr Mark Fletcher, Director of In...Sustained blood pressure treatment lowers dementia risk in elderly
...year of hypertension treatment, there is increased protection against dementia." Some physicians hesitate to tr...f 446 men with normal blood pressure. "We found protection against both Alzheimer's disease and vascular dementia," Peila said. "There is more and more recogn...Significant reduction in antibiotic-resistant pneumococcal disease since the introduction of PREVNAR
...ication to its use. PREVNAR does not provide 100% protection against vaccine serotypes or protect against nonvaccine serotypes....Jefferson researchers discover that nanoparticle shows promise in reducing radiation side effects
...f to two-thirds, which was as good as the level of protection given by Amifostine. "We also showed that the fullerene provided organ-specific protection," Dr. Dicker notes. "It protected the kidney from radiation-induced damage, for example, as well as certain parts of the nervous system." He explains that one...Ovary removal surgery elevates risk for dementia
...trogen due to the ovary removal leads to decreased protection of a woman's brain from cognitive decline, or 2) the ovariectomy is innocent and variations in the genes a woman is born with dictate the need for ovary removal and also prompt development of dementia or cognitive impairment. The researchers hypoth...Hopkins study suggests commercially available antibiotic may help fight dementia in HIV patients
...h HIV proteins. The dose of ceftriaxone needed for protection was well within the range currently used for treatment of bacterial infections. "These results indicated that this class of drugs may prove effective in treating HIV patients with dementia," Rumbaugh says. About 500,000 people in the United States al...Trial shows vaccine against cervical cancer provides long-term protection
... safety profile and provided substantial long-term protection against cancerous cell changes associated with high-risk HPV types. Dr Harper states: "These findings set the stage for the widescale adoption of HPV vaccination for prevention of cervical cancer."...St. John's wort, Echinacea interfere with some drugs by moving them out of the body too fast
...ally considered a clinical indication of decreased protection against pregnancy by the oral contraceptive. Dr. Gorski now is studying the impact of St. John's wort on antihistamines and other pharmaceutical drugs. Dr. Gorski began his research with Echinacea, a herbal preparation often touted for its ability to...COX-2 inhibitors significantly reduce risk of cancer
...ors appears to provide about the same magnitude of protection from prostate, lung and colon cancer. "These results suggest strong potential for regular use of these drugs in cancer prevention. Still, we know these drugs may have side effects, so we are not advising people to go out and start taking them until m...Research suggests that immune response protects against brain tumor development
...t those who use antihistamines could decrease that protection and increase their risk. The real question is if there are particular gene variants that would make a person susceptible." The researchers also asked participants about their history of chicken pox. A latent infection is known to promote low level in...International study questions health benefits of moderate drinking
...lar results. Moderate drinking was associated with protection from premature death in the majority of studies -- those containing the "abstainer error." Protection was not found in the few studies without the error, e.g. where moderate drinkers were compared with long-term abstainers. Previous meta-analyses tha...