Tag: "protein" at medical news
Draining away brain's toxic protein to stop Alzheimer's
...lagues Alzheimers patients: Simply drain the toxic protein
away. Thats the method outlined in a paper publi...ess, dramatically reducing the levels of the toxic protein
in the brain and halting symptoms. The team is now working on developing a version of the protein
New cause of tamoxifen resistance in breast cancer cells discovered at Lombardi
...the effects of XBP1 over-expression occur when the protein
is bound to the estrogen receptor, suggesting for ...he cell. This was the first evidence that the XBP1 protein
may play a role in breast cancer pathways. Through molecular profiling of the downstream effects ...
Chromatin remodeling complex connected to DNA damage control
...the 'beads on the string' is accomplished by large protein
complexes, ATP-dependent chromatin remodeling complexes." In this case, the Ies4 subunit of the remodeling INO80 complex is phosphorylated by ATM/ATR, a necessary step for certain DNA checkpoints to work properly. When Shen and colleagues used a ...
Pathway links inflammation, angiogenesis and breast cancer
HOUSTON - A well-known inflammatory protein
spawns an enzyme that inactivates two tumor-suppre...le in cancer formation related to the inflammatory protein
Tumor Necrosis Factor alpha (TNFa). "What we found is a previously unrecognized role for IKKbeta, ...
Reductive stress linked to heart disease
...f Medicine and the studys principal author. The protein
alpha B-Crystallin, termed a molecular chaperone, ...makes alpha B-Crystallin is mutated in humans, the protein
unfolds improperly into aggregrates, the hallmark of the condition in different organs, including th...
Stanford researchers find culprit in aging muscles that heal poorly
... tissues. The key to the whole process is Wnt, a protein
traditionally thought to help promote maintenance and proliferation of stem cells in many tissues. But in this instance, Wnt appears to block proper communication. "That was a total surprise," said Thomas Rando, MD, PhD, associate professor of neur...
NIH scientists target future pandemic strains of H5N1 avian influenza
...tions in the region of the H5N1 hemagglutinin (HA) protein
that directs the virus to bird or human cells and ...dings build on elegant studies of the influenza HA protein
by structural biologists, notes Dr. Nabel. Insight into the structure of the avian flu virus has ena...
To gain muscle and lose fat, drink milk: study
...im milk, a soy beverage with equivalent amounts of protein
and energy, or a carbohydrate beverage with an equivalent amount of energy, which was roughly the same as drinking 600 to 700 milliliters of a typical sports drink. Upon the studys conclusion, researchers found that the milk drinking group had los...
Drug-eluting stent controversy explored in the American Heart Hospital Journal
...ssels after stenting) and persistence of fibrin, a protein
that indicates blood clotting, when compared with bare metal stents. This delayed healing is the primary substrate underlying all cases of late DES thrombosis at autopsy. In contrast, Drs. Williams and Abbott, of Brown Medical School and affiliated...
Where's the beef? Not enough of it is on elders' plates, muscle-metabolism study suggests
...archers say. And they add that consuming adequate protein
is essential for making and maintaining muscles. S...tudies show that many elderly individuals eat less protein
than the average person, researchers have reasoned that if the elderly simply increased their protei...
Novel candidate biomarker for heart failure also strongly predicts risk of death
...arch team describes finding that blood levels of a protein
called ST2 both indicate the presence of heart fai...MGH published the PRIDE study, which showed that a protein
called NT-proBNP, one of the natriuretic peptides, could confirm or rule out a diagnosis of heart fa...
Green tea holds promise as new treatment for inflammatory skin diseases
...elps by regulating the expression of Caspase-14, a protein
in genes that regulates the life cycle of a skin cell. That marker guides cells by telling them when to differentiate, die off and form a skin barrier, Dr. Hsu says. In people with psoriasis, that process is interrupted and the skin cells dont die ...
W.M. Keck Foundation announces 2007 class of Distinguished Young Scholars in medical research
...rens hopes to define the mechanisms of specialized protein
complexes in excitable cells, such as heart muscle. His research has the potential to explain the underlying causes of certain types of heart failure and cardiomyopathy. Jennifer Zallen, Ph.D., Developmental Biology Program, Memorial Sloan-Ketteri...
Trials underway for 'essential' new TB vaccine
...G, acting as a booster. It uses the 85A antigen, a protein
found in all strains of TB, to boost the response ... vaccine uses a virus as a delivery system for the protein
and the results of the clinical trials to date show the highest T cell responses ever induced with a...
UCLA, Italian chemists move closer to solving Lou Gehrig's disease mystery
...Italy may have solved an important mystery about a protein
that plays a key role in a particular form of amyo...sor of chemistry and biochemistry, has studied the protein
copper-zinc superoxide dismutase since the 1970s, long before it was implicated in ALS in 1993. Si...
Progress toward an antitumor vaccine
...a molecule that is typical for tumors to a carrier protein
without irritating the immune system. As they repo...hey are glycoproteinsmacromolecules with a central protein
chain and long side chains made of polysaccharides. The modified MUC1 would be a good target molecul...
Avian influenza on people's minds
...t. Chicken serves as a popular, low-cost source of protein
for many American families. Indeed, the USDA estim...ses in the prices of alternative sources of animal protein
resulting from higher consumer demands for substitutes for chicken products. As a result, the costs ...
Simple test predicts 6-year risk of dementia
... or subtype, of APO-E, the gene that codes for the protein
known as Apolipoprotein. The presence of APO-E e4 alleles is a known risk factor for Alzheimers disease. A best test score of 0 to 4 indicates a 4 percent chance of developing dementia within six years. A score of 5 to 8 indicates a 25 percent chan...
Study outlines how stroke, head injury can increase risk of Alzheimer's disease
...r head injury may cause generation of amyloid-beta protein
the key component of senile plaques seen in the b...d-beta is formed when the larger amyloid precursor protein
(APP) is clipped by two enzymes beta-secretase, also known as BACE, and gamma-secretase which rele...
Aging stem cells in mice may hold answers to diseases of the aged, Stanford study finds
...ained those cells with a chemical that clings to a protein
that's associated with DNA damage. This protein
can act as a flag to highlight nearby DNA damage. What he found is that young stem cells from norm...
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