Bacteria get off easy in sinus infections
...re severely decreased, and their production of two proteins critical to this defense was 20 to 200 times less ...ectin (MBL) in those whose symptoms returned. The proteins are naturally produced in the nose whenever the immune system detects foreign bacteria or fungi, bin...Newly discovered behavior in cancer cells signals dangerous metastasis
...een the two as their surroundings necessitate. The proteins that the cell produces dictate which way the cell ...order in which DNA is reassembled determines which proteins the gene produces. In cancer cells, the splicing machinery goes awry -- as do myriad functions with...Mutation plays key role in hypertension
...ole, but no gene mutations have been identified in proteins that regulate smooth muscle contraction in essential hypertension. Dr. Yoo-Jeong Han, research associate in physiology and biophysics and lead author of the study, determined the DNA sequence of the stretch of the kinase gene that controls how often...tNOX serves as a serum marker for detection and monitoring of disease progression in prostate cancer
...otein -- called tNOX -- is a member of a family of proteins that are involved in cell growth. Normal cells express the NOX enzyme only when they are dividing in response to growth hormone signals. In contrast, cancer cells have gained the ability to express NOX activity at all times. This overactive form of N...A potential new affordable diagnostic test for TB
...LDI-ToF, ** to identify diagnostic combinations of proteins in the blood for TB. They used blood from patients...ntified two of the possible 20 most discriminatory proteins that could be adapted for use in the field....SARS: No evidence that any of the treatments worked
...ribavirin, lopinavir and ritonavir), steroids, and proteins called immunoglobulins which are found naturally in human blood. The WHO group wanted to know how these treatments affected the virus outside the body ('in vitro') and whether it helped the condition of patients and reduced the death rate, especially...Amateur boxing linked to brain cell injury
...hs later. "The cerebrospinal fluid levels of these proteins increase in disorders with neuronal and axonal degeneration and damage, and the increase is known to correlate with the size of the brain lesion," the authors write. "When applied to the results of this study, the increases in neurofilament protein ...Funding to tackle hospital superbugs
... market." Research into the development of novel proteins discovered by the team led by Professor Topley and Dr Simon Jones has already identified new pathways that enhance the bodies natural defence mechanisms to promote the clearance of infection. The new approach has been named "Resolution Therapeutics"...High chemical levels in blood stream indicate need for action to avoid heart attack, death
...gy. According to the research, high levels of two proteins in the bloodstream indicate that patients with acu... or bypass surgery to treat blocked arteries. The proteins troponin-T (TnT) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) are just two of the bio...Electric jolt triggers release of biomolecules, nanoparticles
...ules; nanoparticles; biopolymers such as peptides, proteins and DNA; and protein assemblies such as viruses, said Searson, who also is director of the Institute for NanoBioTechnology at Johns Hopkins. "The technique is relatively simple, but nothing like this has been done before," he said. "Scientists hav...Live H5N1 avian flu virus vaccines show protection in animal studies
... team created three vaccines by combining modified proteins derived from virulent H5N1 flu viruses with proteins from an artificially weakened (attenuated) flu strain. The virulent H5N1 viruses were isolated from ...Brown seaweed contains promising fat fighter, weight reducer
...ss. That's because fucoxanthin is tightly bound to proteins in the seaweed and is not easily absorbed in the form of whole seaweed. However, he hopes to extract the most active form of fucoxanthin from brown seaweed so that it can be developed into a pill that people can take daily or as needed. Human studi...'Allergy cells' can aggravate cancer and psoriasis
... other places, can stimulate mast cells to release proteins that regulate the recruitment of inflammatory cells. Since it is already known that levels of CD30 are higher in people with psoriasis or atopical eczema and with Hodgkins lymphoma, the results can explain how the mast cells are activated and how the...Mayo researchers discover HIV dependence on a human protein
...nto designs of screens for additional key cellular proteins that HIV either appropriates as partners, as in the case of p75, or schemes to evade. Quite a few more likely exist. The challenge is to use the right methods to find them." How HIV Infects Humans -- Cannot Currently Be Eradicated Each time HIV r...Reconstructive surgeon aims for rejection-free limb transplantation
...imb transplantation with this protocol, which uses proteins called costimulation-blocking antibodies. With current treatment methods, all transplantation patients take medications that reduce the function of their immune systems so their bodies don't reject the foreign tissue. But long-term use of immunosupp...Case and Cleveland Clinic researchers identify molecule in age-related macular degeneration
CLEVELAND--A dart-like molecule that adheres to proteins in the eye is the key that turns on the uncontroll...molecule, Carboxyethylpyrroles (CEPs), attaches to proteins found in the eye, triggering the uncontrolled growth of blood cells. The Case researchers teamed up...Proteins necessary for brain development found to be critical for long-term memory
...out a lifetime." The researchers have shown that proteins known as growth factors are as essential for the i...e researchers used a "molecular trick" to keep the proteins from binding with the appropriate TrkB receptors. For the experiment, the scientists used wild-cau...New findings could lead to vaccine for severe malaria
...te enters human red blood cells, where it produces proteins that attach themselves to receptors in the wall of...lf, and whether it produces many different surface proteins or if one and the same protein is able to bind to many host receptors....Unique results from Swedish study of HIV vaccine
...o stimulate the rapid endogenous production of the proteins for which the injected DNA codes. The trial subjects were vaccinated on three occasions with this vaccine using a needle-free method of injection. In order to enhance the effect, the researchers also gave the subjects a fourth dose of a vaccine in...... to clone five members of the BAG family, says the proteins help regulate heat shock protein 70, which helps other proteins fold and function properly. The BAG family also has an anti-death function called antiapoptosis. Dr....