News tips from The Journal of Neuroscience
...n in the rat spinal cord. The authors found that a rapid increase in GABA A -mediated inhibition in lamina II after hindpaw injection of carageenan was prevented by finasteride (FIN), a blocker of 5αNS production. FIN had no effect in control adult rats, indicating that levels of endogenous 5αNS ...Toward the future of cancer prevention
..., given advances in screening and early diagnosis, rapid developments in genetics and molecular biology, and progress in the treatment of early disease and in next-generation targeted therapies. And finding answers is one of the top goals of The University of Texas M. D. Anderson Cancer Center, which has o...Artificial light at night stimulates breast cancer growth in laboratory mice
...sed subjects stimulated tumor growth. "We observed rapid growth comparable to that seen with administration of daytime blood samples, when tumor activity is particularly high," Blask said. According to the researchers, melatonin exerts a strong influence on the body's circadian rhythm, an internal biologic...New Israeli study finds vaccinating all toddlers against hepatitis A
...he disease, but also offers objective proof of the rapid vaccination-induced reduction of hepatitis A circulation, and the positive effect vaccination can have, on that community." The study presented by Dr. Dagan follows the fluctuation in hepatitis A incidence rates among the Israeli population. Since ...Heart burn medication a risk factor for community-acquired C. difficile
...and prevention techniques, as well as develop more rapid diagnosis for an infection that has become a serious health concern, not just in Quebec but around the world....Research clarifies how brain replenishes memory-making molecules
...nown as AMPA receptors, they are essential for the rapid connections made between nerves during learning. T...placed by receptors from inside the cell to permit rapid regulated changes in the number of receptors, England explained. "Our study suggests that the source...Antibody therapy promising for pediatric neuroblastoma
...tology-Oncology at St. Jude. "We were able to make rapid progress by doing all the development and production of the antibody on campus. Now we're planning to submit a proposal to the Food and Drug Administration to begin a Phase I trial of this strategy that will permit us to begin exploring ways to use t...Benefits of flu vaccine substantially overestimated says study
...ible through school-based vaccine clinics allowing rapid administration of vaccine to large numbers, representing all socioeconomic groups, within a short period of time."...Role of nervous system in fatal heart rhythm under study
...gnals that control the pumping of the heart become rapid and chaotic causing the lower chambers of the heart to quiver instead of contract. Those chambers can no longer pump blood to the rest of the body, which leads to sudden cardiac death without defibrillation a successful emergency shock to jump start...Researchers investigate the case of the disappearing teaspoons
...easpoons are an essential part of office life. The rapid rate of teaspoon loss shows that their availability (and therefore office life) is under constant assault. One possible explanation for the phenomenon is resistentialism (the theory that inanimate objects have a natural aversion to humans), they writ...Medicare drug benefit could do harm to poor, elderly, and disabled
...care and Medicaid Services (CMS) should commission rapid studies to examine the impact of formulary restrictions and changes in cost sharing on the use of essential medication and health outcomes," Soumerai writes. He suggests that CMS should also modify policies that cause underuse of essential medication...Guidelines needed to help care for children during emergencies
...gnitude and severity of these illnesses, requiring rapid assessment and treatment of large numbers of severely ill children. This was seen with the tsunami disaster and the recent earthquake in Pakistan. What we need are simple, easy-to-use guidelines that are brought together in a single package for the d...AstraZeneca and M. D. Anderson Cancer Center form umbrella scientific collaboration agreements
...onal research at M. D. Anderson. "To make the most rapid progress in the era of targeted therapies, we need new ways to organize our research and to collaborate with pharma for the benefit of our patients." AstraZeneca has a strong pipeline of novel cancer agents, including both small molecules and monoclo...Potential treatment for intracerebral hemorrhage under study
...f the main arteries of the brain can benefit from rapid delivery of a factor that is part of the body's natural clotting process. Intracerebral hemorrhage accounts for up to 15 percent of the 750,000 strokes that occur annually in the United States, says Dr. Christiana E. Hall, MCG neurologist and a princ...Mutation that protects against HIV infection may raise risk of West Nile virus illness
...tically engineered to lack CCR5 receptors suffered rapid and uniformly fatal infection by the virus. Further investigation showed that CCR5 promoted the movement of several classes of immune system cells into the brain and central nervous system, which appeared to protect normal mice from the encephalitis ...New compound stops brain cell degeneration in Alzheimer's disease
...rug Discovery and Chemical Biology (CDDCB) for the rapid discovery of new potential therapeutic compounds. ...d. Second, an innovative approach was used for the rapid and cost-effective discovery of orally bioavailable, safe and efficacious compounds, and this approa...Low-level heat wrap therapy safely reduces low back pain and improves mobility in the workplace
...unction with pain management education experienced rapid and significant reduction in pain intensity and greater pain relief when compared to patients who only received pain education. Patients on CLHT showed a 52 percent reduction in pain intensity and a 43 percent improvement in pain relief within one d...Mice studies illustrate potential of chimp/human antibodies to protect against smallpox
...re experienced only slight weight loss followed by rapid recovery. Conversely, all five of the mice that received 5 mg of VIG 48 hours after virus exposure experienced much greater weight loss than those that received the hybrid antibody. "This study demonstrated that the hybrid antibodies provide instant...NFL players show more rapid recovery from concussions than high school players
National Football League (NFL) players showed more rapid recovery from concussions than high school footbal...thletes NFL athletes in this study demonstrated a rapid neuropsychological recovery following concussion. As a group, NFL players returned to pre-injury bas...Studies confirm effectiveness of fentanyl lozenges for 'breakthrough' cancer pain
...esic effect, better global satisfaction and a more rapid onset of action than the usual rescue medication o...through pain is an analgesic with good efficacy, a rapid onset of action, a short duration of action and minimal adverse effects. Irrespective of the drug, t...