Advanced prostate cancer previously considered inoperable may be operable, curable
...y had a cT3 prostate cancer, a more advanced form, rather than what they really had a cT2 prostate cancer in which the malignancy is confined inside the prostate. Dr. Zincke points to following patients over 15 years post-treatment as a strength of the study. "The highest incidence of prostate cancer death ...Study shows new antipsychotic drug prevents brain loss in schizophrenia
...t new patients with atypical drugs like olanzapine rather than older conventional medications such as haloperidol and chlorpromazine." Gray matter contains the bulk of the brains cell's and the billions of connections among the cells. Loss of gray matter in patients with schizophrenia has been linked to so...Carnegie Mellon researchers open window into the ability of humans to recognize faces
...had the opportunity to test: 'I have always been a rather extreme introvert, uncomfortable in groups of people and in social activities. I sort of tend to want to be a hermit. However, I find it relaxing to go window-shopping in a mall. A crowd of a hundred strangers is more relaxing than a dozen neighbors ...BI-RADS lexicon for ultrasound useful for differentiating benign from malignant solid masses
...recommendations to base those decisions on science rather than gestalt. For example, we are taught in general that margins that appear circumscribed at ultrasound are generally seen with benign masses. While this is true in general, our study showed that 10% of masses with circumscribed margins at sonograp...Six organizations vie for INFORMS 'science of better' innovation prize
...eatable method; evaluate key resource requirements rather than relying on past examples; and become a more agile organization that evaluated alternative solutions to emerging problems. PLATO produced overall time and cost saving and reduced required resources without compromising level of service. Its assis...ALLHAT findings are 'color blind' in showing diuretics work better for high blood pressure
...(ALLHAT), confirms earlier findings that diuretics rather than newer, more expensive drugs such as ACE inhibitors, calcium channel blockers, or beta blockers should be preferred as a first therapy for most patients. The multi-center ALLHAT study is conducted under a National Institutes of Health contract wi......meter ultrasonic transducers in transmission mode, rather than the commonly used echo mode, to create the 3-D image. He explains that in traditional hand-held ultrasound systems, sound waves are broadcast into the tissue, and the echoes produce an image of the reflecting interfaces that is, the sound tran...Golf-related head injuries in children increasing along with sport's popularity
...of the injuries occurred in a neighborhood or park rather than a golf course. "But it doesn't matter where you get hurt. It's the same mechanism of injury." Much like a 1996 study in North Carolina that showed a 32 percent increase in golf-cart related injuries in children age 10 and younger, the increasin...Insomnia, falls in elderly linked
...t the real culprit may be the underlying insomnia, rather than the medications used to treat it. Residents w...ese concerns did not look to see whether insomnia, rather than the drugs themselves, might be the problem," says senior author Ronald Chervin, M.D., M.S. "Our...Study reveals drinking alcohol reduces breast milk supply in women
... who are breast feeding reduces their milk supply, rather than boosting it. New evidence shows that alcohol consumption causes hormonal disruption, decreased lactation performance and diminished milk supply. The findings were published today in the April issue of The Journal of Clinical Endocrinology & Meta...Dr. Gutin selected as Fulbright Senior Specialist
...siological factor, was how fat they were. It was a rather surprising and clear-cut finding." Years of research and the growing waistlines of Americans have clarified the true impact of fatness and unfitness. "Now, most epidemiologists would say it's more a predictor of future mortality than anything else, i...ISHLT updates guidelines for heart and lung transplants
... "We do not intend to throw wisdom out the window, rather we want to update widely held beliefs and offer continued support of relevant concepts," Mehra says. "There is a lot of knowledge out there that is robustly worthy of our support."...'Promiscuous' area of brain could explain role of antidepressants
... receptors had to turn off and become desensitized rather than be stimulated," Dani said. "That didn't make ...we assumed they're a little promiscuous. That is, rather than transporting one neurotransmitter, these systems may transport other neurotransmitters as well....Liver may be source of 'good' cholesterol
...t that HDL formation occurred throughout the body rather than coming mainly from one organ. They know that some of it is manufactured in the walls of blood vessels, for example. "These results profoundly alter our concept of how HDL is manufactured in the body and establish the liver as the single most imp...Blood test can accurately diagnose heart failure in emergency patients
...valuated potential heart failure patients has been rather random, with some receiving a physical examination and medical history while others also get expensive and time-consuming procedures," Januzzi says. "Having a widely-available, accurate, and cost-effective diagnostic method would be of extraordinary...Location of body fat associated with cardiovascular risk even at normal body weight
...in the deeper tissues and around the body's organs rather than just under the skin) was associated with metabolic syndrome in older men and women whether they were normal weight, overweight or obese. Subcutaneous (under the skin) abdominal fat was associated with metabolic syndrome only in normal weight men...Exercise may not be good enough to reduce mild hypertension in older people, Hopkins experts say
...l stiffening causes higher systolic blood pressure rather than higher diastolic blood pressure, and older pe...to immediately bring blood pressure under control, rather than relying strictly on exercise, although a comparison of exercise to drugs requires further study...Obesity and insomnia linked by excitability of brain cells
... cutting back on stressful aspects of their lives, rather than trying to specifically medicate either insomnia or obesity." Obesity and metabolic disorders are a major cause of death and illness in the United States, with one of the highest financial burdens on the health care system....Columbia research suggests need to rethink causes of heart failure
... e.g. anemia, obesity, hypertension and diabetes - rather than the treatments currently prescribed specifica...art size similar to that of a healthy 25 year old, rather than taking into account that this disease predominantly affects elderly women, who have smaller hea...Adverse outcomes from blood clot therapy may be due to patient characteristics, not dosing errors
...east in some situations, may be due to confounding rather than a direct effect of the error itself." "Thus, while medication errors need to be minimized, caution should be used in concluding that adverse outcomes associated with errors are primarily caused by the errors. Importantly, more research is needed...