Tag: "rats" at medical news
Statin simvastatin linked to protection against endothelial dysfunction in diabetic rats
...iabetes in rats, then treated half of the diabetic rats
with simvastatin. After four weeks the untreated rats
had high levels of cholesterol and various indicators of endothelial dysfunction in the vessels of t...
Onion compound may help fight osteoporosis
...tained a group of isolated bone cells from newborn rats
and exposed the cells to parathyroid hormone to stimulate bone loss, then exposed some of the treated cells to GPCS. Treatment with GPCS significantly inhibited the loss of bone minerals, including calcium, when compared to cells that were not expose...
OHSU scientist helping explain basis of psychotic behavior
...hers used mice bred to lack the D2 gene as well as rats
treated with PCP, alcohol, amphetamine and other dopamine-inducing drugs. They found that while there were small increases in the total population of D2 receptors among the animal models, the increases were small compared with the jump in densities o...
Chemical present in clear plastics can impair learning and cause disease
...ist at Yale, found that low doses of BPA in female rats
inhibit estrogeninduction of synaptic connections in the hippocampus, an area of the brain involved with expression of sexually differentiated behaviors, as well as with formation and retention of memory. Although estrogen is best known as one of the...
Rats with migraines provide Jefferson scientists insights to improved drug strategy
When Michael Oshinsky, Ph.D., gives his rats
a headache, he has good reason. The animals are helping Dr. Oshinsky, assistant professor of neurology at Jefferson Medical College of Thomas Jefferson University in Philadelphia, study how migraine treatments work. In recent experiments, the animals...
Hormone aids recovery in rats with hemorrhagic stroke
...red blood cells, has shown a therapeutic effect on rats
who have suffered an intracerebral hemorrhage, acc...otective effect and improve functional recovery in rats
following an intracerebral hemorrhage, which is a type of stroke. "This is the first evidence that e...
Tea may help prevent diabetes and cataracts
...y. Researchers fed green and black tea to diabetic rats
for three months and then monitored the chemical composition of the rats' blood and eye lenses. At levels that would be equivalent to less than five cups of tea per day for a human, both teas significantly inhibited cataract formation relative to a c...
Propensity for obesity, diabetes, may occur in utero
...s showed, but islets from 12-day-old suckling 2-HC rats
showed a capacity for insulin oversecretion when m...proximately 4 days after weaning to rat chow, 2-HC rats
once again had high insulin levels and showed a higher capacity for insulin secretion to a glucose s...
Two studies offer clues about how alcoholic behavior is 'switched' on
...ain's reward center decreased drinking behavior in rats
trained (see: http://www.bnl.gov/bnlweb/pubaf/pr/...cohol consumption. They tested their hypothesis in rats
with a genetic predisposition to prefer alcohol when given a choice between a 10 percent ethanol sol...
Study suggests antibiotic may limit or prevent vision problems caused by diabetes
...eurons critical for normal vision. "Our studies in rats
suggest that this antibiotic may be a strong candi...red the mRNA levels of cytokines in the retinas of rats
with diabetes to healthy rats. Increasing mRNA levels are an indicator of increasing cytokine produc...
Can rice bran oil melt away cholesterol?
...rol. The results: The most effective dose in rats
was 8 IU kg/day. Extrapolated to humans, a person with an average body weight of 154 pounds would get around 560 IU, which is close to the 400 IU of Vitamin E normally taken. (The upper tolerable intake of Vitamin E is 1500 IU). Researchers have b...
Researchers prevent post-traumatic brain damage
... surrounded by a scar, whereas the brains in those rats
treated with the experimental drug, Flavopiridol, ... and motor function recovered, Faden said. "These rats
were no different from the ones that had not experienced brain injury," he said. The approach that F...
Study shows grapefruit extract can heal stomach ulcers
...the study, investigators induced gastric ulcers in rats
and applied graded doses of GSE (2-20 mg/kg) to me...ssue with fibrous scar tissue). Male and female rats
were divided into groups and given either no alcohol (IC) or alcohol (AF) in a higher carbohydrate d...
Discovery of a 'drug anticipation' brain signal
...imally small recording electrodes in the brains of rats
to detect the release of the neurotransmitter dopa...th taking such drugs. The researchers first taught rats
to self-administer cocaine by pressing a lever when a light in their cage came on. They next extingu...
Narcotic drugs effective for severe, chronic pain in older patients
... no study had systematically evaluated how quickly rats
develop tolerance to opioid pain medication as a f...at source. The researchers found that the youngest rats
experienced drug tolerance more than five times sooner than the oldest rats. Six-month-old and three...
Researchers study natural products that may prevent certain cancers
...radiation induced inflammation and skin damage and rats
against certain forms of heart muscle damage following chemotherapy treatment. Curcumin is the yellow pigment of the spice turmeric. Based on studies that showed dramatically reduced rates of colon cancer in populations with diets rich in curcumin, ...
In those genetically predisposed, 'developmental reprogramming' could explain cancer risk
...p in adulthood. While the study was conducted with rats
that are susceptible to benign uterine tumors, and... Cook and their team designed a study using female rats
that are genetically predisposed to development of uterine leiomyoma, the same kind of benign fibroi...
Animal model demonstrates course of epilepsy
...rlying brain malformations lead to epilepsy in the rats
in adulthood. The article is available via Wiley I...rrent study, the researchers found that when these rats
reach adulthood, almost all develop temporal lobe epilepsy. Furthermore, they have deficits in learn...
New memory drug works best in combination with older remedy
... team conducted this study on 60 normal young male rats
who were not memory-impaired. Each rat was given a...iously ate all the available food. So we asked the rats
to remember where they had found treats in the 'information' session, and to look for food in new pl...
Brain's own marijuana-like chemicals play key role with stress-induced pain relief
...algesia in response to pain stimuli. Further, when rats
used in study were given a small molecule inhibitordeveloped by Piomelli and his collaborators, stress-induced analgesiaincreased dramatically, proving the connection between pain suppressionand the release of these marijuana-like compounds. The inhi...
1 2 3 4 5 6 7 8