Tag: "reactive" at medical news

Penn study finds pro-death proteins required to regulate healthy immune function

...ion, a key by-product of energy production, called reactive oxygen species or ROS, were not produced. And beca...equently, the release of ROS. It is the release of reactive oxygen species by the mitochondria that actually generate the proliferation. We think that is the ba...

NIH scientists target future pandemic strains of H5N1 avian influenza

... mutant receptors, and they discovered one broadly reactive antibody that could neutralize both the bird- and human-adapted forms of an H5N1 virus. According to Dr. Nabel, their findings should contribute to better surveillance of naturally occurring avian flu outbreaks by making it easier to recognize dan...

New oxidation methods streamline synthesis of important compounds

...rbon-hydrogen catalysts that are highly selective, reactive and tolerant of other functionality. The catalysts also offer a new strategy for streamlining the synthesis of important compounds, including drugs and pharmaceuticals, by avoiding the functional group manipulations required for working with oxidiz...

Progress toward an antitumor vaccine

...cause the protein portion of the molecule has many reactive groups that are attacked in the coupling reaction. In addition, says Kunz, many of the structures that make suitable anchors are themselves highly immunogenic, which can suppress the immune response against the true target, the glycoprotein. This te...

World first medical treatment announced by researchers

...ccurs when the production of free radicals, highly reactive chemicals, outweighs antioxidant defences. This leads to a great deal of damage to cells, and in particular DNA, the cells blueprint, and is likely to be responsible for the fibrosis, as the lungs try to repair the damage done by free radicals. In...

JCI table of contents -- May 17, 2007

...oundation report that Cdelta-CS B cells are highly reactive to self antigens. Future studies will be important to determine the mechanism by which the majority of Cdelta-CS B cells are autoreactive and may provide insight into the enigmatic function of the IgD antibody, with the goal of understanding the acti...

World-leading innovation in child-allergy detection

...also allow doctors to keep allergens in their best reactive state, the powdered form. The materials used in 'DIALLERTEST' patch tests are all bio-compatible, specially conceived for the pharmaceutical industry. At the beginning of 2006, new investors SOFINOVA and APAX contributed 12 million euro to DBV Tec...

Effectiveness of first renin inhibitor drug for treating hypertension is limited

... Hypertension. The authors report that, because of reactive renin secretion, this drug has not been any more e...rtensive capabilities can be counteracted by large reactive increases in renin secretion; this is particularly likely at higher dosage. Writing in the article...

Comparison of patients' access to new and better cancer drugs reveals inequalities between countries

...l budgets, preferably on a proactive basis and not reactive basis i.e. by planning ahead. Dr Jnsson concluded: "We believe that the inequalities between countries in patients' access to cancer drugs cannot persist. Cancer patients will not accept that a standard of care available in one country is not avai...

Cause of gender differences in blood pressure, kidney damage under study

...se hypertrophy, it can stimulate the production of reactive oxygen species, so it does all sorts of bad things... cortex, she also finds males have too many highly reactive and potentially damaging free radicals. Free radicals or reactive oxygen species have important job...

Eating cured meats frequently can lead to lower lung function and potential COPD

...olor fixative," said Dr. Jiang. "Nitrates generate reactive nitrogen species that may cause damage to the lungs, producing structural changes resembling emphysema." Although certain rodent studies suggest that inhalation of nitrogen dioxide may contribute to emphysema, no other human studies to date have ex...

DOE commits $27.5M for uranium contaminant transport field studies

...hat can then be used to develop effective flow and reactive transport models." Researchers look forward to initial analysis of microbial protein expression during field-scale bioremediation. These data will make it possible to learn what nutrient factors are most important for achieving maximum rates of ...

Synthetic production of potential pharmaceuticals dramatically simplified by Scripps research team

..., which are extra compounds chemists use to shield reactive portions of a molecule during specific stages of a...ps are eventually cleaved chemically to expose the reactive portion during later chemical reactions to complete a product's synthesis. Each protecting group use...

Molecular differences between early and advanced melanomas could provide new drug targets

...Akt overexpression was the increased production of reactive oxygen (ROS). Reactive oxygen is created during ce...wth melanoma cells into highly invasive tumors via reactive oxygen pathways," says Dr. Arbiser. "This could provide us with promising targets for anti-cancer d...

New treatments prevent brain injury hours after stroke in rats

...because brain cells are suddenly exposed to highly reactive and unstable oxygen molecules, which are toxic. The researchers found that NAD+ reduced brain cell death from reperfusion by 70 to 86 percent compared with rats not given the treatment, according to lead author Weihei Ying, PhD, a research scienti...

Obesity could bankrupt the health system, warn doctors

...anges to prevent excess weight gain but are simply reactive to their environment, say the authors. What is provided is what is eaten so what is provided has to change, they add. Thus education alone will fail to halt this obesity epidemic, and environmental changes (physical, food, and fiscal policy) are u...

SARS: No evidence that any of the treatments worked

...ploits a new finding in a mouse model that lack of reactive oxygen species makes arthritis worse rather than, as had been expected, better in a mouse model with arthritis. Reactive oxygen species are thought to be important in defense against pathogens. The researcher tested phytol, which increased oxidative ...

Keep slapping on that sunscreen

...anson's team found that the samples contained more reactive oxygen species (ROS) than skin exposed to UV with no sunscreen on it. ROS are free radicals that can damage skin cells and increase the risk of skin cancer (Free Radical Biology and Medicine, DOI: 10.1016/j. freeradbiomed.2006.06.011). The Skin Can...

Sunscreens can damage skin, researchers find

...s that then can generate harmful compounds, called reactive oxygen species or ROS, which are highly reactive molecules that can cause "oxidative damage." For example, ROS can react with cellular components lik...

Researchers discover how acid reflux leads to esophageal cancer

...ses the activation of NOX5-S and overproduction of reactive oxygen species (ROS), thereby increasing cell growth and decreasing cell death optimal conditions for cancer to develop. It was previously known that levels of ROS are increased in Barrett's Esophagus and in esophageal cancer and that ROS may play...

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