Survival differences by race most apparent in advanced stages of breast cancer
...n may be exacerbated by the more complex treatment regimens used for more advanced breast cancer. ...Medical residents score poorly in diagnosing and managing tuberculosis
...f the questions about the toxicity of current drug regimens and about the link between TB and HIV infection, physicians gave the right answer (with a median score of 63 percent for both questions.) Despite the poor results for trainees, people cannot assume that lack of comprehensive knowledge about tuber...U-M study finds lymphoma drug effective over long term
... those achieved with state-of-the-art chemotherapy regimens that take months to deliver. But Bexxar is given as a single treatment, completed within one week, which makes it an extremely convenient regimen for patients," Kaminski says. Non-Hodgkin's lymphoma, the nation's sixth leading cause of cancer death...Herceptin does not increase heart failure in patients long term
... terms of choice of Herceptin-containing treatment regimens based on their personal risk and benefits, said Dr. Rastogi. ...GSK's Pazopanib shows positive results in patients with advanced renal cell carcinoma
... to standard chemotherapy, and immunotherapeutic regimens using recombinant human interleukin-2 (IL-2) and recombinant human interferon -2b (IFN-), either alone or in combination, have been widely used in patients with advanced disease. Although high-dose IL-2 has shown promise with durable complete remiss...GSK's Pazopanib shows positive results in patients with advanced RCC and ovarian cancer
... to standard chemotherapy, and immunotherapeutic regimens using recombinant human interleukin-2 (IL-2) and recombinant human interferon -2b (IFN-), either alone or in combination, have been widely used in patients with advanced disease. Although high-dose IL-2 has shown promise with durable complete remiss...Gene variations point to why lung cancer drugs work better in Japanese vs. US patients
...of pharmacogenomics, which promises to tailor drug regimens to a patients genetic profile. Nobody else in the world has ever done this, with a common arm looking at genetic differences among ethnic groups, Gandara says. Researchers looked at DNA from 156 patients who received the chemotherapy drugs paclitax...VEGF Trap shows activity in patients with advanced ovarian cancer
... who had received three or four prior chemotherapy regimens and had become resistant to platinum-based chemotherapy agents. The findings, which are being presented today at the American Society of Clinical Oncologys annual meeting, may indicate a role for this targeted therapy in women with ovarian cancer who...Treatment outcomes of patients with HIV and tuberculosis
...ue of the journal, future HIV-related TB treatment regimens and relapse studies should broaden their focus to ...ance. They suggest that short-course, intermittent regimens may be necessary in areas where resources are limited, and that additional research on regimens (inc...Hepatitis B patients' understanding of infection and treatment deficient
...long disease and often do not comply with the drug regimens necessary to control it, according to a new UCLA s...ed, which could result in better adherence to drug regimens and improved clinical outcomes. The results of this study are very compelling and are a wake-up ca...New guideline for treating Lyme disease
.... Patients who have received accepted antibiotic regimens for Lyme disease sometimes have persisting symptoms, often referred to as Post-Lyme syndrome (PLS). This guideline states that long-term use of antibiotics does not improve the outcome in people with chronic symptoms after customary treatment of Lym...Certain combination therapy found more effective for treating malaria in African children
... malaria. However, it is not clear which treatment regimens are most effective. Grant Dorsey, M.D., Ph.D., o... evaluated the three leading available combination regimens for treating uncomplicated falciparum malaria (one of the most severe types of malaria, with one of ...Ulcerative colitis sufferers find UC quite disruptive to many aspects of daily life
... to address is compliance. More convenient dosing regimens such as once-daily dosage formulations may be part of the solution." Bridging the physician/patient gap Patients are also normalizing their experiences with flare-ups, a serious worsening of UC symptoms. UC patients reported an average of eight fl...Atypical pathogen treatment vital in hospitalized CAP patients
...ty-acquired pneumonia (CAP) who received treatment regimens against atypical disease-causing pathogens reached clinical stability quicker, had fewer days of hospitalization, and had lower mortality rates as a result of their disease, according to a large new study. The research results appear in the second ...Genetic markers in surrounding tissues linked to breast cancer tumor grade, presence of metastases
...gnized for decades that identical chemotherapeutic regimens for similar stage and grade in patients with, for example, breast cancer (or virtually any malignancy) respond differently. The complexities of genetic alterations in breast cancer may provide a primary basis for these consequent (secondary) clinicop...Once-a-year drug reduces fractures from osteoporosis
...ffective as current monthly or weekly osteoporosis regimens at reducing the incidence of bone fractures, accor...Black said. "Adherence to these weekly and monthly regimens is often a problem, so an annual treatment means patients are far more likely to actually receive va...Other highlights in the May 2 JNCI
...treatment with rituximab and standard chemotherapy regimens should be considered the standard of care for patients with indolent and mantle cell lymphomas who require therapy and for patients with follicular lymphoma," the authors write. Contact: Holger Schulz, holger.schulz@uni-koeln.de , +49 221 7107701...New class of HIV drug attacks previously untargeted enzyme
...me an important component of combination treatment regimens used to treat heavily pretreated patients failing current therapies with multidrug-resistant virus and limited treatment options." In an accompanying Comment, Dr Pedro Cahn and Dr Omar Sued, of the Fundacin Huesped, Buenos Aires, Argentina, said th...Combined imaging approach may provide better identification of difficult-to-diagnose brain clots
...one day help physicians formulate better treatment regimens and possibly prevent more serious medical complications for certain patients. "If we can more easily characterize the patients problem as chronic instead of acute, it could alter the way we prescribe anticoagulation (clot-busting) drugs to treat th...Drug used to prevent HIV transmission from mother to child damages DNA
...cy. Most, but not all, of the prenatal treatment regimens in this study included AZT. At birth, the researchers observed ten-fold increases in the frequencies of micronucleated reticulocytes (MN-RET) in the women and infants whose prenatal drug regimen included AZT. No increases were detected in the women...