Clinical trial evaluates first-line approaches for treating HIV
... The researchers found all three of the treatment regimens were potent, producing substantial increases in CD4+ T cell counts and decreases in HIV viral load. After 96 weeks of treatment, 89 percent of the participants randomized to the efavirenz arm had "undetectable" levels of HIV, meaning viral load was l...Exercise helps sustain mental activity as we age, may prevent dementia-like illnesses
...ramer. He cautions that different fitness training regimens and aspects of mental functions need further study to solidify a causal relationship. But, he added, there are some preliminary positive findings. In a four year study looking at the relationship between physical activity on cognition and brain funct...Africans much better than North Americans at taking anti-HIV meds
...on of poor adherence by Africans to antiretroviral regimens that was offered as a rationale to delay providing these therapies. If one had considered adherence simply on the basis of evidence, Sub-Saharan Africans would have had access to these life-saving therapies earlier," said study lead author Edward Mil...Sub-Saharan Africans with HIV may achieve favorable levels of antiretroviral therapy adherence
...ding to background information in the article. The regimens are often complicated, can include varying dosing ...t should be noted that the complexity of treatment regimens is potentially greater in North America, which should be considered when interpreting the data," the...National trial gives 'unprecedented' support for steroid withdrawal in kidney transplants
...d to further quantify the benefits of steroid-free regimens and their impact on health risks to provide the ve...pressive combination. "We know that steroid-free regimens are being employed with increased frequency across the United States," he says. "This study provides...Taking medicine regularly (even placebo) is good for you
...e hypotheses "could yield extra value in treatment regimens that patients agree to, believe in, and will sustain over time."...New data at ASCO show CAMPTOSAR is key to treating 1st line metastatic colorectal cancer
...FL and CapeIRI , two alternative chemotherapeutic regimens containing CAMPTOSAR used to treat metastatic colo...OS when compared to mIFL plus bevacizumab and both regimens were tolerable."...New study re-evaluates cardiovascular risks of anti-inflammatory drugs
...re needed to identify which anti-inflammatory drug regimens minimise serious cardiovascular and gastrointestinal problems. An accompanying editorial discusses other options for treating chronic pain and suggests that doctors work with their patients to choose the best solutions for them....New biomarkers for improving treatment of spondylarthritis
... at early time points across different therapeutic regimens and to combine synovial assessment with predictors of axial response to treatment in SpA."...Biologic therapies lead evolution of Crohn's treatments
...erely active CD. The team compared two ADA dosing regimens in maintaining clinical remission (CDAI<150) at 26 and 56 weeks in patients with active disease who had already responded to open-label (OL) induction therapy with ADA. A total of 854 patients received OL induction with ADA. After four weeks of ...Procedures beat meds to help patients fight obesity, GERD
...e efficacy of individual versus combined treatment regimens in attempt to further reduce symptoms. Results demonstrated that patients who managed symptoms with a class of medicines called proton pump inhibitors (PPI) and underwent laparoscopic Nissen fundoplication (LNF) experienced a significant reduction i...Best settings for biphasic automated defibrillators investigated
...ate a difference in other outcomes between the two regimens but was not powered to do so. This is the first randomized trial to compare fixed and escalating biphasic energy regimens, and it found more successful termination of VF and conversion to an organized rhythm for secondary shocks with the escalating r...Choice of chemotherapy before liver metastasis surgery matters for some patients
...ed to the liver by these preoperative chemotherapy regimens can adversely affects long-term surgical outcomes. Use of chemotherapy before surgery offers several important benefits, including reducing the size of tumors such that they are more easily removed and, potentially doubling the survival rate. Results...Almost 1/3 of colon cancer patients stop chemotherapy, leading to double the death rate
...ncer patients, need to complete their chemotherapy regimens whenever possible. Previous studies have shown that not completing chemotherapy regimens for breast cancer is associated with shorter survival. This is the first study to look at a link be...Cancer therapy based on anatomical location may soon be obsolete
...reatments -- which have established different drug regimens for brain, prostate or ovarian cancer, for example -- should eventually be replaced with therapies that use drugs deemed to be of highest benefit based on the tumor's pharmacologic profile. Treatment choice would be determined by how each patient's t...Benefit of chemotherapy in breast cancer depends on estrogen-receptor status
...searchers also compared the different chemotherapy regimens tested in the trials, and found the latest chemotherapy combination studied - biweekly doxorubicin/cyclophosphamide plus paclitaxel - lowered the rate of recurrence and death in ER- patients by more than 50 percent, compared to the low-dose regimen u...Newer chemotherapies improve outcomes for some types of breast cancer
...Cancer Intergroup. The trials compared (1): three regimens of cyclophosphamide, doxorubicin, and fluorouracil (January 1985 to April 1991); (2) three doses of doxorubicin concurrent with cyclophosphamide, with or without subsequent paclitaxel (May 1994 to April 1997); (3) sequential doxorubicin, paclitaxel, ...Advances in chemotherapy improve outcomes in select breast cancers
... overall survival rate with the newer chemotherapy regimens was 16.7 percent for ER-negative patients and 4 percent for ER-positive patients. "Our observations add to a growing body of evidence that breast cancer is not one homogeneous disease, but rather a disease with many subtypes and requires a variety o...New international standards for tuberculosis care published
...copy in making diagnoses, often use incorrect drug regimens and can fail to supervise adherence to treatment, which can lead to drug-resistant forms of the disease. Private healthcare professionals are also less likely than providers in government programs to assume responsibility for controlling the spread o...Maintenance treatment prevents recurrence in older adults with single-episode depressions
...rs tested the effectiveness of different treatment regimens in keeping patients symptom-free for up to 2 years. These patients were randomly assigned to one of four maintenance treatment groups: (1) paroxetine; (2) placebo; (3) paroxetine and monthly interpersonal psychotherapy (IPT); and (4) placebo and IPT....