UT study reveals inaccuracies in cardiac PET-CT imaging, finds fixes
...rity of coronary artery disease, for following its regression or progression, and for identifying mild early non-obstructive coronary atherosclerosis as the basis for intense, lifelong pharmacologic and lifestyle management, the publication states. PET-CT is a valuable tool in the detection and management of ...Extended duration work shifts risky to the safety, well-being of medical interns, patients
..., completing a total of 17,003 monthly reports. A regression analysis was performed to determine the relationship between the number of extended duration work shifts (greater than or equal to 24 hours in length), reported medical errors and a self-reported measure of stress. It was discovered that the report...GSK announces launch of largest ever Phase III trial in lung cancer treatment
...60 patients receiving placebo (43.3%). Using a Cox regression model to adjust for the fact that patients in the different arms were enrolled in the study at different times, there was a 27% reduction in the relative risk of cancer recurrence following surgery, compared with placebo (p=0.107). Although the study...New drug shows promise in treatment of advanced thyroid cancer
The investigational drug axitinib produced tumor regression or stable disease in almost three-out-of-four patients with advanced thyroid cancer, a research team reported at the annual meeting of the American Society for Clinical Oncology in Chicago. In this exploratory phase-2 trial, 18 out of 60 patients ...Erectile dysfunction -- the canary in the mineshaft?
... records of the subjects were examined. Logistical regression models examined the associations between ED and CVD. Men with CVD were 4.2 times more likely to have ED than men without heart disease. The results underscore a need to consider sexual function in men with heart disease and CVD in men with ED. This...Dealing deadly cancers a knockout punch
...th agents, test animals experienced enhanced tumor regression compared with either agent alone, and without additional toxicity. Oncolytics has permission from the U.K. regulatory authorities to test Reolysin in three separate human trials in combination with the cancer drugs gemcitabine, paclitaxel/carboplatin...Therapeutic unshackles p53 and causes tumor regression
...treatment with Nutlin-3a induced substantial tumor regression in mice with established human PEL, reactivation of p53 using Nutlin-3a might provide a viable therapeutic for the treatment of individuals with PEL. ...No benefit for liver cancer patients from long-acting octreotide
...ol group had died after a median 5.3 months. Tumor regression did not occur in any patient. The six month survival rates were 41 percent for patients in the octreotide group and 42 percent for patients in the control group. The placebo group reported 169 side effects, compared to 161 reported by the octreotid...Infectious disease researchers develop basis for experimental melanoma treatment
...owth was completely inhibited and near total tumor regression occurred in those animals with smaller tumors (0.6 to 0.7 cm in diameter). Further, the treated mice showed no signs of kidney or other organ damage and none died during the 30-day study. Conversely, tumors continued to aggressively grow in the untre...Manmade protein shows promise for cancer, macular degeneration
... he says. The work shows the intraceptor prompts regression of blood vessels by inducing programmed cell death, or apoptosis, in the vascular endothelial cells that line the vessels. "The biology of all this is showing this molecule interrupts the proper folding of proteins involved in existing blood vesse...Innovative surgery corrects vision in kids with neurological disorders
...of life, most laser-treated children will see mild regression in their vision over time and about 10 percent require repeat surgery, Tychsen says. But for most parents, the decision to have their child go through the surgery is relatively simple. "For special-needs children, there is often no alternative," Ty...New cell-based targets for treating autoimmune inflammatory diseases
...n expression, defect in platelet function, and the regression of crescent formation in the glomerulus. What's more, these links are related to BLOC-1, which controls lysosomes, tiny organelles that contain digestive enzymes critical to maintaining healthy cell function. "The profound role of BLOC-1 ...Placebo study frames depression treatment puzzle
...ed using a statistical tool called multiple linear regression analysis. Final outcomes were determined using Hamilton Rating Scale for Depression scores. The study found that decreases in cordance in the prefrontal brain region during the placebo lead-in period were associated with lower depression-scale score...High estrogen levels associated with dementia in older men
...eloped vascular dementia. The researchers used Cox regression analyses, adjusting for age and other covariates, to see if hormone levels were associated with risk of developing dementia "Levels of bioavailable testosterone were not associated with risk of cognitive decline and incident dementia," they report....Encouraging results for folic acid as a cancer prevention drug
...lements may prevent cancer progression and promote regression of disease, according to a new study. Published in the July 15, 2006 issue of CANCER (http://www.interscience.wiley.com/cancer-newsroom), a peer-reviewed journal of the American Cancer Society, the small study found that 31 of 43 patients with the pr...ACTOS (pioglitazone HCl) to be studied in new trial
...is studying the effects of ACTOS on progression or regression of atherosclerosis in the coronary arteries using intravascular ultrasound."......e utility of statistical model-based inference and regression in delineating key task parameters that may be represented in spatially distinct brain regions," they concluded....Nano-particles effective in killing cancer with one-two punch of chemotherapeutics
...of paclitaxel and doxorubicin lead to better tumor regression than either drug alone, but there hasn't been any carrier system that can carry both drugs as efficiently to a tumor," said Fariyal Ahmed, the lead author, former doctoral student in bioengineering,and now a fellow at Harvard Medical School. "Polyme...American Indians with alcohol problems have more medical conditions
...ity confidentiality.) Study authors used logistic regression to examine associations between self-reported alcohol abuse/dependence and 19 medical conditions. "Medical conditions that had significant relationships with alcohol abuse/dependence were sprains and strains, hearing and vision problems, kidney and b...Very high-intensity statin therapy shows promise for inducing regression of coronary atherosclerosis
..., increased HDL-C levels by 15 percent, and showed regression of coronary atherosclerosis, according to a study ...2;0.98 percent and 63.6 percent of patients showed regression of atherosclerosis. For the second primary efficacy parameter, change in atheroma volume in the 10-m...