Three-fold risk of sudden cardiac death from some non-cardiac drugs
...A." He concluded: "These findings are important to regulatory authorities because QTc prolongation is used as a surrogate marker for the prediction of serious adverse drug effects and the authorities have to evaluate the clinical significance of QTc prolongation observed in relatively small clinical trials wher...Exercise in cold water may increase appetite, UF study finds
..., particularly those with joint disorders, thermal regulatory problems and balance or coordination difficulties," she said. "However, an earlier study reported that women who swam did not lose as much weight as those who jogged or cycled." For her study, published in February in the International Journal of Sp...Microbicide partners receive $5.7 million from Gates Foundation
...ck the microbicide pipeline, clarify and influence regulatory processes, problem-solve, and conduct research and convene participants around critical issues. "Without the generosity of the Gates Foundation, our efforts to develop microbicides would be delayed by years," said Polly Harrison, Director of the Alli...Guava and AHF Global Immunity bring low cost AIDS diagnosis to resource-limited countries
...s for use on the Guava EasyCD4 system. A number of regulatory organizations around the world have indicated that new guidelines for HIV/AIDS diagnosis and monitoring will recommend the use of CD4 percent tests for monitoring pediatric HIV/AIDS patients. About the Guava EasyCD4 The Guava EasyCD4 system and a...Substituting nurses for doctors results in high quality care, few savings
...ower overall costs. The ANA advocates for removing regulatory and legislative barriers to increased use of nurses as health care providers. The systematic review included 16 studies totaling more than 25,000 patients in the United Kingdom, United States and Canada. The review appears in the most recent issue of...Kidney donation program may provide more matches for previously incompatible recipients and donors
...Organ Procurement and Transplantation Network, but regulatory obstacles to a national program still exist; therefore, no data exist regarding the impact of national vs. regional programs. Dorry L. Segev, M.D., of the Johns Hopkins University School of Medicine, Baltimore, and colleagues developed a novel kidney...Mercury levels and cognitive function investigated in adults
... type are critical to the development of effective regulatory policies," said Brian Schwartz, MD, senior author of the study and a professor in the Bloomberg School of Public Health's Department of Environmental Health Sciences....Researchers find that chocolate compound stops cancer cell cycle in lab experiments
...the novel aspect here is that a pattern of several regulatory proteins are jointly deactivated, probably greatly enhancing the inhibitory effect compared to targeting any one of the proteins singly. That is also why the compound seems to work on cancer cells, irrespective of whether any of these single genes a...Competition in health care may not result in better quality
...luate the benefits and costs of competitive versus regulatory policies. "The health care environment is complicated and multi-layered, and perhaps the most effective change may require a mix of approaches involving competition and regulation to ensure patient safety and quality of care. For example, the automot...Belgium doctors treating critically ill infants favour legalising euthanasia
... in the Netherlands despite its new, more liberal, regulatory system of such actions. In an accompanying comment Chris Feudtner (Children's Hospital of Philadelphia, USA) outlines five issues in the euthanasia debate. He states: "If we want a policy that would reduce acts of killing to a minimum, we need far b...Scientists discover way to control allergic reactions
...e allergic reactions by increasing numbers of CD4+ regulatory T-cells. Dr Mark Larch from Imperial College Londo...ns. Although we have known about the role of these regulatory immune cells for a number of years, this is the first time we have found a way to manipulate them to...Pezcoller Foundation-AACR International Award for Cancer Research
...D., M.D. (h.c.). "In addition to opening up a key regulatory pathway of oncogenesis that is manifested in many, if not most human malignancies, they also provide opportunities for drug targeting of PI3K or downstream effectors. "Indeed, many such drugs are in clinical trials for cancer and are expected to also...