Reanalysis of controversial meta-analysis says writing off rosiglitazone may be premature
...gs but stopped short of calling for the drug to be removed from the market. "The original meta-analysis employed one statistical model, but there are other approaches that deserve consideration as well. Only when different methods give us the same answers should we be confident in the results," say Diamond...Controlling prescription drug expenditures: a case report of success
...ver a drug was changed to a more expensive tier or removed from the formulary, the members out-of-pocket costs were the same or less if they changed to the less-expensive alternative. The interventions included reclassifying select brand-name drugs to non-preferred status (resulting in approximately half o...Method shows promise for early detection of pancreatic cancer
...n the pancreas. (Resectable means the tumor can be removed surgically, which in this study is defined as stage 1 or 2 tumors.) Some people were identified who did not have a tumor; it is uncertain whether this is a false finding or if it means those people could be at risk for developing pancreatic cancer an...Speeding up CT scans with cellphone technology, ultrasound warning signal for breast cancer
... insulator (a dielectric). When most of the air is removed from the tube to create a vacuum, the tube can structurally withstand the very high electric-field gradations necessary for accelerating protons to high energies in a short distance. In addition to its smaller size, a DWA-based proton therapy sys......nding to cells, whereas the dye molecules stay far removed from the metal nanoparticles and thus retain their bright fluorescence. Many cancer cells, including those implicated in cancers of the ovary, kidney, uterus, testis, brain, colon, and lungs, tend to overexpress folic acid receptors. Owing to the fo...Brightening prospects of using fluorescent nanotubes in medical applications
... of Nanoscale Science and Engineering (VINSE) have removed an obstacle that has restricted fluorescent nanotubes from a variety of medical applications, including anti-cancer treatments. In a paper published online in the Journal of the American Chemical Society on June 7, they describe a method that can suc...Folic acid supplements do not appear to reduce risk of colorectal tumors
... large intestine among individuals with previously removed adenomas. The evidence for an increased risk of adenomas is equivocal and requires further research. In view of the fortification of the U.S. food supply with folate, and some suggestions that folate could conceivably increase the risk of neoplasia e...Doctors, engineers develop new wireless system to detect esophageal reflux
...RFID chip to the esophagus, where it remains until removed by a physician. The chip, about two square centimeters, or a little bigger than a dime, tests for electrical impulses that signal acidic or nonacidic liquids moving through the esophagus. It then transmits data to a wireless sensor worn around the ne...Increasing radiation dose shortens treatment time for women who choose breast sparing treatment
...me period, the lumpectomy site where the tumor was removed was treated with a high-dose radiation "boost." The standard "boost" is typically administered after the four to five weeks of whole breast irradiation and adds another one to two weeks to the treatment time. Fox Chase radiation oncologist Gary Fr...'Nurse cells' make life and death decisions for infection-fighting cells
...ies, it was suggested that thymic nurse cells only removed non-functional thymocytes," said Eve Barak, program director in NSF's Division of Molecular and Cellular Biology. "This research shows that nurse cells are performing a much bigger role in the thymus than we thought." Thymic nurse cells were given ...'Smart' mice teach scientists about learning process, brain disorders
...rning. The new research showed that when Cdk5 is removed from the brain, the levels of NR2B significantly increase, and the mice are primed to learn, Dr. Bibb said. "We made the animals smarter, but in doing so and applying this technology, we also found biochemical targets that hold promise for future ...Breast MRI may help determine surgical management of women with newly diagnosed breast cancer
...y instead of lumpectomy, 21 women whose lumpectomy removed more tissue than originally planned, and five patients who had surgery on both breasts. Following surgery, the researchers compared the actual appearance of the cancer to the original mammogram or ultrasound and also to the MRI. The change in surgi...Vacuum cleaning ineffective in allergy avoidance
... vacuum cleaners with rotating brushes in the head removed more dirt and allergen from the carpets than those without. However, rotating brushes may serve to kick dust up into the air if the suction component of the cleaner is not operating properly. For the first time, the study demonstrated that carpet...Veterans exposed to Agent Orange have higher rates of prostate cancer recurrence
... If it sounds odd that men who had their prostate removed could have disease recurrence, Dr. Terris points out that microscopic cancer cells can migrate out of the area before surgery, becoming detectable later when they start pushing PSA levels back up. In fact, following any type of prostate cancer trea...Exposure to mercury preservatives before birth is no higher in children with autism
...demy of Pediatrics, recommended that thimerosal be removed from all routinely recommended early childhood vaccines; this was accomplished by 2002. The current study investigated thimerosal exposure during pregnancies that resulted in the birth of a child subsequently diagnosed with autism. Rh negative wo...Thymus transplants gives hope to babies with fatal immune disease
...all or part of it to gain access to the heart. The removed thymus tissue is grown in culture for several weeks in a laboratory while researchers ensure that there are no diseases present in the tissue. Strips of tissue are then implanted in the baby's thigh, where they attract a blood supply and begin to act...Novel catheter technique successfully patches holes in the heart
...al months after device implantation. The patch was removed and all 3 patients had successful surgery to repair the rupture. Even in such cases, the VSD patch serves its purpose by allowing patients to regain enough strength to withstand surgery, Dr. Martinez said. "Surgery is the long-term answer for some...Study confirms health benefits of whole grains
...tioxidants, and healthy fats. These are the parts removed in the refining process, leaving behind the energy-dense but nutrient-poor endosperm portion of the grain. Examples of whole grain foods include wild rice, popcorn, oatmeal, brown rice, barley, wheat berries and flours such as whole wheat. In addi...Increasing survival of organ transplant patients by reducing time interval for transported organs
...ecifically the interval beginning when an organ is removed from the donor and is cooled with the solution, to the time when the organ is implanted. Conversely, the Organ Care System (OCS) is based on warm blood perfusion technology, which it uses to maintain organs in a warm, functioning state. This sta...... assume that by so doing you have kept them safely removed from humans for the next 2.3 million years."...