News briefs from the journal CHEST, April 2005
...educational program dramatically reduced equipment repair costs for endoscopes and associated equipment at B...rt of the IP program, the hospital's average daily repair cost was $42 per procedure. After the IP program was introduced to the hospital, repair costs rose ...Chemical library aids in developing drug system for nerve damage
...finity, or attraction, to a sugar that binds nerve repair drugs called heparin, as well as a nerve repair protein called nerve growth factor. Sakiyama-Elbert ran a library of viruses called bacteri...Heart valve ring reverses damage from congestive heart failure, easing symptoms
..., and will be marketed as the GeoForm mitral valve repair ring. Both the co-inventors and the U-M stand to b...at happened in some patients who had typical valve repair or replacement. The Geoform ring, and the Acorn device, Bolling says, should also give heart failur...Cancer research could lead to improved detection methods
...l's pre-cancerous state. This initiates the cell's repair system, which fixes errors or leads damaged cells to die. "If, however, the overall process fails because of an overload of an overload of carcinogens and the cell is not killed, this leads to multiplication of damaged cells which may develop in into...New treatment for hereditary breast cancer
...the treatment and continue to use recombination to repair any mistakes that occur." -- Since normal cells don't need the PARP backup system to survive we could use PARP inhibitors as a prophylactic treatment to kill BRCA deficient cells before they grow out to tumours, says Dr Thomas Helleday, associate pr...Variant in gene associated with telomeres predicts longer survival of deadly brain tumor
...ifferent genes associated with cancer, such as DNA repair genes and p53, but this is the first time we have found a genotype that has such a large effect on clinical outcome."...Researchers develop 'genetic blueprint' to predict response to esophageal cancer treatments
... believed to be involved in metabolism, DNA damage repair activity and action of these of therapies. Next, t...herited less effective variants of a base excision repair gene (XRCC1) that repairs DNA damage from radiation exhibited longer survival. Those with the GG var...NIH awards funding to biotech firm for heart disease
...nt study to test the safety of using stem cells to repair ischemic heart tissue caused by an inadequate blood supply to the heart. The balance of the funding from the NHLBI is expected to be awarded later this year, contingent on successful completion of the Phase I study. Arteriocyte is a start-up compan...Revised Bethesda guidelines effective at identifying patients at risk of colorectal cancer
.... Ninety-one patients (7.4 percent) had a mismatch repair deficiency. The researchers found that strategies based on either microsatellite instability testing or immunostaining patients according to the revised Bethesda guidelines were the most effective (sensitivity, 81.8 percent and 81.8 percent; specific...Giving children access to drug clinical trials is crucial, clofarabine approval shows
...timetabolite, works by blocking the production and repair of DNA, the building blocks of genes. The drug was developed to improve the efficacy and minimize the toxicity of two similar drugs, cladribine and fludarabine. The other author of this paper is Peter Kirkpatrick (Nature Reviews/Drug Discovery)....Latest research and emerging treatments for osteoporosis focus of NYAS conference
...nto five broad themes: skeletal development and repair molecular endocrinology of bone bone cell biology conservation of skeletal integrity current and emerging therapies for osteoporosis. Each section will offer participants to engage in a focused discussion within each category. The Keynote Speaker...Scalpel-free surgery could reduce risk of HIV and hepatitis exposure for health care workers
...d skin clips or glue instead of sewing to close or repair wounds. Previous studies have shown that health care workers are injured in about 7 percent of operations. As many as 87 percent of surgeons will receive an injury that breaks the skin -- thus allowing for possible disease transmission - at some ...Infants with rare genetic disease saved by cord blood stem cells
... from adult bone marrow, and cord blood stem cells repair deficiencies in both the central and peripheral nervous systems, said Kurtzberg. Thus, disease progression stabilizes about 2 to 4 months earlier in patients who receive cord blood compared to those who receive adult bone marrow, and huge developme...High blood pressure causes pathological scars in the heart
...ts not only prevent damage to the tissue, but also repair the tissue damaged. 30% of the adult world population has high blood pressure and half of these shows LVH and are, thus, prone to the consequences of myocardial fibrosis. This data means that, of the 8 million people with high blood pressure currentl...Investigating 'brain shrinkage' in alcoholics
...role in cognitive deficits as well as recovery and repair of the brain. Together we can develop strategies for public education and new approaches to therapy in people who use and abuse alcohol. People who abuse alcohol," he added, "should be informed that some of the brain damage could be reversed."...Study shows importance of exposure age for Hanford nuclear workers' cancer risk
...ngs declines in immune function and the ability to repair genetic damage," Wing said. Although radiation risks were higher for older workers in the UNC study, it would be inappropriate to conclude that younger people are not at risk, he said. He and Richardson could not examine cancers that did not lead to ...Knowledge of Tuskegee study doesn't increase medical mistrust
...at a tremendous amount of work needs to be done to repair the trust of African Americans with the medical system, which has direct implications for clinical trials and research," said Lydia A. Isaac, coauthor of the study. The Hopkins researchers also analyzed the relationship between race and mistrust of t...Neural cell transplants fight immune attack in mice with multiple sclerosis
...ng ways to fight the immune attack and protect and repair brain tissues in people with MS. Background: In r...cent years, scientists have been exploring ways to repair the damage of brain and spinal cord tissues during the course of the immune attack in MS. Evidence s...Experts discuss use of human stem cells in ape and monkey brains
...using human stem cells as treatments to replace or repair brain cells lost in conditions like Parkinson's disease or Lou Gehrig's disease. "We agreed to disagree about whether non-human primates should be used for invasive biomedical procedures at all, and to focus instead on whether experiments with stem ...CryoSat environmental testing over preparations for shipment to launch site about to begin
... the components were functioning and consequently, repair and replacement activities hampered the testing programme and slightly delayed the launch date. Now, however, there just remains the final software checks before the satellite and its support equipment are packaged for the long voyage to Russia for l...