Heart care lacking for those with clogged leg blood vessels
...ceived a molecule called a poloxamer that may help repair tissue and reduce inflammation. The other group received the poloxamer together with an injected gene for a protein that stimulates blood vessel growth. Now, Grossman leads a trial at U-M comparing poloxamer against placebo. Other research on agents...Engineered blood vessels may be an option in cardiac bypass
...iting potential application for pediatric coronary repair because this is a living product and can grow with the patient. Another potential benefit of the approach is that coronary bypass patients could eliminate the injury and surgical complications associated with harvesting blood vessels from the legs."...Statins may simulate stem cells for heart repair
...ogenous stem cells that may participate in cardiac repair independent of any cholesterol-lowering action. T...lated from bone marrow currently are being used to repair damaged heart tissue," Suzuki said. "Many animal and early clinical studies using this source of st...Magnetic probe successfully tracks implanted cells in cancer patients
... cancer or prevent its recurrence or stem cells to repair damaged organs, say the researchers. Bulte and a team of Dutch researchers used MRI and a magnetic probe approved by both European and U.S. agencies to locate therapeutic cells injected into eight melanoma patients. "Our results show that the MRI-b...Feinstein Institute neuroscientist wins top honor in Parkinson's research
...brain function, and how treatment can successfully repair these abnormal brain pathways. We hope that this work will now continue to help us design newer and better therapies for Parkinson's disease patients," Dr. Eidelberg said. Dr. Eidelberg specializes in utilizing positron emission tomography (PET) to l...New research targets treatment for dementia and brain injuries
...tified a process that could lead to development of repair mechanisms for people suffering from dementia and acquired brain injury. The research reveals discoveries in the hippocampus a part of the brain commonly associated with memory function where the brain's ability to regenerate nerve cells or neuron...Iron particles and MRI could replace biopsies to track stem cell therapy and deploy stents
...damaged areas of the heart and were able to effect repair and improve heart function," says study senior co-investigator Jeff Bulte, Ph.D., an associate professor in radiology at Hopkins who developed the labeling method. In other experiments in rabbits and dogs, the researchers successfully used the IRON m...Bayer launches Phase III clinical study of Trasylol in elective spinal fusion surgery
... allowing surgeons to treat injuries to the spine, repair broken vertebra, correct deformities, adjust abnormal curvatures, stabilize weakness and remedy slipped or herniated disks. Approximately 300,000 spinal fusion surgeries take place each year in the United States, a figure that has doubled in the last...Toward the future of cancer prevention
...c control that could explain susceptibility is DNA repair capacity. These systems help maintain the integrit...t of cosmic X-rays and UV light. If errors in this repair system occur, DNA damage can result in unstable genes and an increased cancer risk. "Some peo...Melanoma risk only partially associated vith exposure to UVB from sunlight
...melanoma patients often have a reduced capacity to repair the DNA damage that results from UV exposure. In the novel study, researchers looked at how often chromosomes break in cells from skin cancer patients compared with cells from a control group. Wei and his team of 16 collaborators at M. D. Anderson ...Smoking while pregnant causes finger, toe deformities
...r defect by 29 percent. "Reconstructive surgery to repair limb, toe and finger abnormalities in children represents a large portion of my practice it is the most common issue I treat," said Benjamin Chang, MD, ASPS member and study author. "Parents would ask why this happened to their child, but I didn't h...An engineer, a dentist, a veterinarian build bone tissue
...ismal statistics might yield a better outcome. The repair of the diseased tissue in these cancers often requires reconstruction of the bone, and Brian Love, Virginia Tech professor of materials science and engineering, and principal investigator on a $140,000 National Institutes for Health (NIH) grant, beli...Caloric restriction appears to prevent primary aging in the heart
... example, you cut yourself, your body will work to repair the damage by activating fibroblasts to produce collagen and make scar tissue to heal the wound. Fontana says the low levels of TNFa, CRP and TGFb, combined with evidence of "younger" hearts in people on caloric restriction, has led his research tea...Exercise is linked to later onset of dementia and Alzheimer's disease
...at exercise may prevent damage and might even help repair these areas by increasing blood flow." Larson advises older people that it's never too late to begin exercising. "Even if you're 75 and have never exercised before, you can still benefit by starting to exercise now." Simply walking or swimming for 15...Delaying surgery for hernia repair a safe option
Men who delay surgical repair of a hernia until the hernia becomesuncomfortable ...nd of the two years.Patients who received surgical repair reported significantly greaterimprovement in their ability to perform a range of everyday activities...Delaying surgery is a safe, acceptable option for some men with hernia
...se men and their physicians sometimes delay hernia repair until emergence of pain or discomfort. Surgical re...annually and watched for hernia symptoms; surgical repair patients received standard open tension-free hernia repair and were followed up at 3 and 6 months an...Mayo Clinic collaboration discovers protein amplifies DNA injury signals
... MDC1 amplifies weak DNA injury signals so genetic repair can begin. Once amplified, even low-level damage s...ecome strong enough to activate the cell's natural repair processes while the injury is most tractable to repair. How this "distress call" was communicated wa...Stem cell study seeks to prevent heart failure
...rate. When humans receive an injury too serious to repair through regeneration, a process called fibrosis ki...hey can rush to the site of damage to aid in wound repair the same way that white blood cells rush in to fight infection. Also like white blood cells, MSCs ...Viral, gold nanoparticles can assemble themselves to potentially find and treat disease
...potentially morph into tissue needed to internally repair the wound, the researchers say. "This is our vision of the future, and, of course, it all needs to be further studied and translated into real clinical applications," Arap says. "But we can now think in those terms because of this pioneering work tha......le repair. The researchers found that these muscle repair cells, satellite and side population (SP) cells, a... turns out that an adult muscle cell's capacity to repair damaged muscle is directly related to where it comes from, and this has implications for the potenti...