Researchers take aim at the causes of heart valve disease
...ell documented 100,000 U.S. surgeries per year to repair or replace damaged valves -- but doctors still know very little about the causes. Rice University bioengineer K. Jane Grande-Allen hopes to change that by designing a laboratory apparatus that will allow valve testing under the same chemical and mech...Hope for arthritis stems from within
...ve developed an innovative technique for cartilage repair combining the self-healing powers of the body with...hom. "Orthopaedic surgeons are looking for ways to repair cartilage defects in young people which will delay, maybe even prevent, the need for total knee repl...Stem cells from muscles can repair cartilage
...disease. Treatments and experimental approaches to repair this articular cartilage have achieved limited res...ineered with a therapeutic protein in an effort to repair articular cartilage defects in rats. Led by Johnny Huard, PhD, director of the Growth and Developmen...When we say the wrong thing...repairing the message
... studied how and why people choose certain ways to repair the damage done once hurtful words are spoken. Acc...essage predict a certain response? Is the type of repair strategy linked to the kind of relationship the person has to the message's receiver? How do emotio...Minimally invasive procedure OK for wide range of aorta problems, study shows
...research shows, a minimally-invasive procedure can repair a wide range of problems in the upper part of the aorta, the giant blood vessel leading out of the heart. In this region, called the thoracic aorta, the intense force of blood pulsing out of the heart can rip the aorta's walls apart or cause them to ...OHSU research reveals the complexities of obesity/cortisol interactions
...ain or peripheral tissues, scientists attempted to repair the problem and counteract the obesity by manipulating POMC and glucocorticoid levels. The scientists did this using two methods. One method was to genetically restore POMC selectively in the pituitary, a gland at the base of the brain that regulates...IU School of Medicine scientists testing stem cells for peripheral artery disease
...ecause of genetic factors. As a result, they can't repair or replace damaged blood vessel cells, and heart d... turn, it's hoped, they will promote blood vessel repair and the growth of new blood vessels by stimulating the production of special protein growth factors.......ys. "We aren't sure why, but we think that the DNA repair machinery may be involved in processing the Z-DNA structure differently in bacteria versus human cells." Since formation of Z-DNA is naturally occurring and can exist in the genome, the scientists next want to understand why cells can sometimes proce...Neuronal receptor response may help explain Alzheimer's memory loss
...quick energy, to store as fat for later use, or to repair wounds. But researchers now know that APOE does more than distribute lipids, especially in the brain. About a decade ago, scientists linked APOE4, one of the three common forms of APOE, to development of Alzheimer's disease, although the biological l...Seminar examines biology of pain and nerve repair in peripheral nerve disease
... pain mechanisms and peripheral nerve development, repair and regeneration. Speakers include Rhona Mirsky of University College, London; Elior Peles of the Weizmann Institute, Israel; Jeff Milbrandt of Washington University in St. Louis; Stephen Waxman of Yale; Bill Snider of the University of North Caroli...Man-made heart tissue improves cardiac performance
...sed to treat cases of myocardial infarction and to repair congenital heart defects, as well as in the use of drug development to provide insight into cardiac developmental biology....Multiple sclerosis research into reparative cells offers new avenue for fighting disease
...t over from development that could be activated to repair the damage, he said. The problem is how to trigger them to grow. "Those are progenitor cells that will grow up into mature cells," Dr. Frohman said. "We know more why they don't grow up." Proteins called repressor proteins keep the OPCs in an immatu...'Stent-graft' procedure improves outcomes of carotid aneurysm repair
...inimally invasive treatment using a stent-graft to repair the carotid artery aneurysm (CAA) has become a use...rtery. The researchers compared the results of CAA repair in two eras: 1985 to 1994, when 22 patients were treated by open neck surgery; and 1995 to 2004, wh...Less-invasive technique has improved outcomes of aortic aneurysm repair
... reduced the risk of death for patients undergoing repair of dangerous abdominal aortic aneurysms (AAAs), re...and prolonged recovery time. Endovascular aneurysm repair (EVAR) provides a less-invasive alternative to open surgery for AAA repair. In this procedure, the ...New study reveals promising osteoporosis treatment
...te drugs and hormone therapies, do not effectively repair bone that has already been lost. In fact, bisphosp...h may also focus on using Mg/Zn/F-CaP compounds to repair fractures and periodontal bone defects....Growth-factor therapy improves endothelial cell production and mobility in arterial disease
...maged vessels and either make new blood vessels or repair the damaged ones. The Emory scientists hypothesized that if the body uses its own growth factors to stimulate production of endothelial progenitor cells, then endothelial dysfunction in PAD would improve if additional progenitor cells were mobilize...Measuring artery repair cells could become new heart disease test
...alized cells that circulate in the bloodstream and repair damage to the arterial lining has been discovered ...r levels of circulating EPCs would be less able to repair cardiac damage. Thus, they would be those with greater disease and at greater risk for a cardiac eve...MIST study explores link between migraines and hole in heart
...al the PFO. To definitively determine whether PFO repair can eliminate migraines, the MIST trial studied 147 patients with severe, frequent migraines and a medium-to-large PFO, randomly assigning them to PFO closure or a sham intervention. Fifteen medical centers participated in the study. PFO closure is ...Refinements and innovations enhance safety, effectiveness
... scheduled for coronary artery bypass grafting, or repair or replacement of a heart valve. Patients were randomly assigned to one week's pretreatment with 40 mg of atorvastatin, or to placebo. Atorvastatin is most often prescribed for lowering blood cholesterol levels, but has also been shown to prevent i......rch on the efficacy of stem cell therapy for heart repair has shown benefit from mesenchymal stem cells (oft...ll eventually be able to use our own stem cells to repair our own heart dysfunctions," said Sunichiro Miyoshi, M.D., of the Keio University in Japan, and one ...