Community MRSA is re-emergence of 1950's pandemic
...as evolved from the earlier 80/81 type, developing resistance to meticillin antibiotics over the last 30-40 year...those currently regarded as at risk. The increased resistance to antibiotics of the community acquired MRSA clone over its 80/81 ancestor mean that there could al...American Thoracic Society Journal news tips for April 2005 (first issue)
...d that almost all tuberculosis strains had primary resistance to only one drug. Treatment with a 2- to 3-month three-drug phase, followed by 2 drugs, became the world standard. Yet patients had to take the regimen for 12 months. In 1956, researchers in Madras, India, found that results from those who were tr...Institute of Medicine news: Review of HIVNET 012 study
...t of other recent studies of potential toxicity or resistance buildup associated with the use of nevirapine either in short- or long-term treatment of HIV-infected individuals. Because of inconsistencies in and challenges to previous audits, the committee undertook its own assessment of the accuracy and complet...Location of body fat associated with cardiovascular risk even at normal body weight
...yslipidemia (elevated blood lipid levels), insulin resistance and high blood pressure, affects 22 percent of adults in the U.S. and an even higher (42) percent of older men and women, according to background information in the article. In addition to overweight and obesity, patterns of fat distribution in middl...Nanotechnology's miniature answers to developing world's biggest problems
...ages by improving shelf-life, thermo-stability and resistance to changes in humidity of existing medications; 6. Food processing and storage: including improved plastic film coatings for food packaging and storage that may enable a wider and more efficient distribution of food products to remote areas in less i...Will cancer vaccine get to all women?
...st be screened and treated. If there is widespread resistance to vaccination, it will take even longer for its benefits to become clear. Vaccines are producing good results in clinical trials, and the first could be licensed as early as next year. GlaxoSmithKline announced in November 2004 that its vaccine, wh...One-meter waistline predicts high risk of diabetes and heart disease
...f one meter or more are at serious risk of insulin resistance - an early stage in the development of diabetes an...ay. No easy test exists for predicting the insulin resistance of an individual. Current guidelines suggest a cut-off for heart disease of 102 cm in men and 88 cm ...Drug can reduce bodyweight and cardiovascular risk factors in obese people
...scular risk factors including cholesterol, insulin resistance and prevalence of metabolic syndrome. The pattern of weight loss seen with rimonabant was sustained for around 36-40 weeks. The most common side effects leading to study discontinuation were depressed mood disorders in all treatment groups; withdrawl...Gene expression pattern predicts multiple drug resistance, treatment failure in pediatric leukemia
...pattern of gene expression linked to multiple-drug resistance of leukemic cells is giving researchers crucial in...n appears in the April issue of Cancer Cell. Drug resistance is a major cause of treatment failure, and the biochemical mechanisms responsible for de novo resist...American Heart Association telephone news briefing
...University of Colorado study. Obesity and insulin resistance in teens Teens who have insulin resistance combined with obesity were more likely to have cardiovascular risk factors, such as higher blood pre...Drugs targeted at muscle cells
... Type 2 diabetes is that they eventually develop a resistance to the insulin and no longer respond to the treatment," say Anna Krook and Juleen Zierath, two of the KI research scientists behind the study. "The PFAAR drugs we have studied, on the other hand, have a direct effect on the cultivated muscle cells an...Researchers develop 'genetic blueprint' to predict response to esophageal cancer treatments
...platin who had particular variants of a multi-drug resistance gene (MDR). Proteins produced by this gene prevent cisplatin from entering cancer cells, and variants of the gene (CT and TT) that are less effective at doing so provide more therapeutic benefit to patients, Wu says. Patients with CT variant had a me...UT Southwestern sports medicine doctor pedals advice on gearing up for safe cycling season
...t riding techniques. If you pedal slowly with high resistance (using the big chain ring and smaller cogs), you c...in your quadriceps or knee. Pedaling fast with low resistance can cause increased pressure on the base of your pelvic region and back, said Dr. Palacios, who has ...10 years before malaria vaccine is ready for widespread use
...tive, even in areas where there is a high level of resistance to other antimalarial drugs. (See this week's issue Lancet 365; 1467-73, Lancet 365; 1474-1480) Insecticide-treated bed-nets provide a simple but effective means of preventing malaria, especially with the development of longlasting nets in which ins...Anti-malaria drug combination could help address treatment crisis in Africa
... way to treat malaria in the areas of Africa where resistance to commonly used malaria drugs is high, concludes ...he disease is rife. This, along with the fact that resistance to sulfadoxine-pyrimethamine is spreading rapidly, has led to strong calls for the introduction of c...Reducing malarial transmission in Africa
...a in the fight against malaria is drug resistance; resistance to chloroquine (CQ), the cheapest and most widely ...sed antimalarial, is common throughout Africa, and resistance to sulfadoxine-pyrimethamine (SP), the first-developed and least expensive alternative to CQ, is als...Exercise slows development of Alzheimer's-like brain changes in mice, new study finds
...rough which exercise and environment might promote resistance to development of cognitive changes that come with aging and AD," Snyder notes. "It is as though exercise or environmental enrichment forces the metabolism of amyloid precursor protein through a pathway that is less harmful and might even be benefici...Discovery of a 'molecular switch' could lead to new ways of treating infection, including MRSA
... health issues, including MRSA. With antibacterial resistance on the rise, this development could provide doctors with a new way to stop infections without resorting to a cocktail of antibiotics. "Although this is only a first step, the discovery could also help arthritis sufferers. By increasing IKKa activity ...New prognostic markers help identify risk of relapse
... ALL respond well initially, 20% will develop drug resistance and will relapse with reduced chance of recovery....UT Southwestern researchers show new drug may help treat certain forms of leukemia
...Dr. Ilaria's lab is continuing research in Gleevec resistance and looking at combining this new compound with other drugs. "CML patients may soon have multiple choices with Gleevec and any one or all of the additional classes of drugs in development," Dr. Ilaria said. "These compounds also may work on other sol...