Experimental gene therapy 'abolishes' arthritis pain and lessens joint damage
...tions of the work may include amplifying the bodys response to morphine, drastically reducing the amount needed for powerful pain relief," Tallents said. "A little further out, the new idea that peripheral inflammatory diseases like arthritis can lead to brain inflammation may provide an entirely new way to t...New reforms could cut the number of unexplained infant deaths
... standard routine for a collaborative multi-agency response to every sudden unexpected infant death, detailing what is expected from ambulance crews, A&E staff, child protection co-ordinators, coroners, GPs, midwives, paediatricians, pathologists, police and social workers. Two key changes are that police...Chinese space agency joins the International Charter 'Space and Major Disasters'
...a joint initiative that works to provide emergency response satellite data free of charge to those affected by disasters anywhere in the world. China National Space Administration (CNSA) Administrator Prof. Dr Sun Laiyan signed the Charter on 24 May at ESA headquarters in Paris, France, in the presence of E...NHLBI Asthma Clinical Research Networks and ALA ACRC Network to present at ATS 2007
... more in-depth information about the predictors of response to inhaled steroids and long-term changes in the p...t of overweight and obesity on asthma severity and response to asthma therapy. The study is using data from the NHLBI on approximately 1,200 people with asthma....Investigational nonstimulant Guanfacine XR significantly improved child, adolescent ADHD symptoms
...mptoms of ADHD in children and for assessing their response to treatment. This scale, which contains 18 items, is based on the ADHD diagnostic criteria as defined in the APA's Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision. In the first trial, 301, investigators comp...Daytrana provides significant effectiveness in both boys and girls with ADHD
...al studies have examined gender differences in the response to ADHD treatments. Our study documented that DAYTRANA offered a favorable safety profile and was an effective ADHD treatment in both boys and girls," said Robert Findling, M.D., lead investigator and Professor of Psychiatry at Case Western Reserve ...Efficacy and safety of Aripiprazole as adjunctive therapy in major depressive disorder
...pressants in patients who did not have an adequate response to ADT alone. (1)(Berman, 2007, APA Poster) Thes...th major depressive disorder who had an inadequate response to one or more ADTs. After a seven to 28-day screening phase, adults in this study underwent an eig...Erectile dysfunction and lower urinary tract symptoms
...ion of whether LUTS severity can impact a patients response to ED treatment. Researchers used data from a randomized, double-blind, placebo-controlled study examining the safety and efficacy of tadalafil in men with moderate to severe benign prostatic hyperplasia (BPH) to perform this post-hoc analysis. Of ...Inhaled steroids may not be enough for some children with asthma
... their inhaled steroid treatment. But variation in response to inhaled steroids, as other medications, is well described. The data comes from the Child Asthma Management Program Continuation Study (CAMPCS), one of the largest groups of children with mild to moderate asthma in the nation who have been follow...New prevention, treatment methods for patients with painful bowel inflammation
...ond to 5-ASA. After 12 weeks of therapy, clinical response was achieved in 23 patients (44%) treated with rosiglitazone and 12 patients (23%) treated with placebo. Patients treated with rosiglitazone had higher rates of clinical remission, but not endoscopic remission. Furthermore, patients who took rosigl...Research highlights from Thoracic Society Conference
... dust-mite allergens, which eliminates an allergic response in 95 percent of cat-allergic people, 92 percent of dog-allergic people, and 60 percent of dust mite-allergic people....New study demonstrates that Lubiprostone may improve symptom relief rates in adults with IBS-C
... were nearly twice as likely to achieve an overall response from symptoms of IBS-C compared to those receiving...ily were nearly twice as likely to achieve overall response compared to those receiving placebo (lubiprostone 17.9 percent vs. placebo 10.1 percent, P=0.001). ...Scavenger cells may have role blocking obesity, Stanford study shows
...ogens, triggering other immune cells to aid in the response to a pathogen. But in recent years, macrophages found in fat tissue of obese animals have been fingered as the source of chemical signals that exacerbate the problems of obesity and insulin resistance that accompany eating too much fat. In this vil...MIT reports key pathway in synaptic plasticity
...f a neuron for long-term synaptic strengthening in response to subsequent stimulation. "A mechanism like the BDNF/PSD-95 pathway could account for numerous observations at the cellular level in animal models, or during behavioral development in young children," explains Yoshii. "Namely, the development of p...Erectile dysfunction -- the canary in the mineshaft?
...s the connection between body mass index (BMI) and response to sildenafil in patients with ED and LUTS. Men with scores less than or equal to 25 on the Erectile Function domain of the International Index of Erectile Funcation and an International Prostate Symptom Score greater or equal to 12 were given 50 m...Cure for hepatitis C announced by VCU researcher
...fected HCV and HIV, who achieved a sustained viral response (SVR) following treatment with either Pegasys (peginterferon alfa-2a) monotherapy or combination therapy with Pegasys and ribavirin. After successful treatment, researchers monitored serum levels of HCV once a year for an average of 4.1 years (rang...The hepatitis C link: Diagnose, treat, transplant
...) as they were shown to have a prior HCV treatment response of ≤0.4log10 to optimized therapy. In the present study, the mean decrease in HCV viral loads in these null responder patients was 1.86 log10 IU/mL with celgosivir plus peginterferon alfa-2b and ribavirin while the two null responder patients ...Could statins be a new option for hepatitis C patients?
... PI+R plus a statin to measure the sustained viral response (SVR, negative virus in blood six months after the end of treatment) rate in hepatitis C patients. A modified intent to treat approach was taken to compare the therapy alone to the therapy with addition of a statin. In this study, 104 patients ta...Bali bomb lessons helped shape Australia's mental health response to terrorism and trauma
...ical area and they initiated a new phase of trauma response for public health services in the country" says An...oyal Darwin Hospital. "A national mental health response to mass trauma was established and this proved particularly useful to the Royal Darwin Hospital, whi...25,000 needless deaths each year due to failure to tackle blood clots in hospital
...ert group's report and the chief medical officer's response were published last month, recommending that every adult should have a mandatory VTE risk assessment on admission to hospital and that core standards be set to ensure full compliance with these assessments. But despite the huge evidence base for pr...