New strategy could prevent leading cause of maternal death in Africa
...cilities. So strategies are needed to increase the safety of deliveries attended by unskilled birth attendants, say the authors. "Our trial suggests that misoprostol would play an important part in such a strategy to reduce complications of delivery and maternal mortality," they conclude....Promote use of drugs to prevent AIDS infection, researchers urge
... disoproxl fumarate or TDF, which has an excellent safety record. Gilead, the company that developed it, has established a global access program that will allow it to be sold at cost in 95 countries. It also plans to set up a non-exclusive licensing agreement with a drug manufacturer in South Africa. "I thi...Novartis MS drug shows promising results
... month on the study drug. There were no unexpected safety findings during the extension as compared to the six-month placebo-controlled phase. The most frequently reported adverse events in patients treated up to twelve months were non-serious infections (colds, influenza), headache, diarrhoea and nausea. ...Many pediatricians say they would not continue care for families who refuse vaccines
...accines were similar. The most common reasons were safety concerns, concern at giving multiple vaccines at once, philosophical reasons and religious beliefs. "In the case of parents refusing specific vaccines, 82 (28 percent) said that they would ask the family to seek care elsewhere; for refusal of all v...Use of pulmonary artery catheterization does not show benefit for severe heart failure patients
... of recently published clinical trials testing the safety and efficacy of the PAC. The researchers located ...ents. "Our meta-analysis of 13 RCTs evaluating the safety and efficacy of the PAC demonstrates that use of the catheter neither improves outcomes in criticall...Children and adolescents with advanced cancer can make complex end-of-life care decisions
.... "But Phase I studies are designed to look at the safety and proper levels of an investigational drug, and not effectiveness," she noted. "So we found it remarkable that young people would knowingly offer to participate in studies to help other children in the future even though they themselves would never...Early treatment of macular degeneration with macugen may help patients preserve their vision
...l, multi-center trial to evaluate the efficacy and safety of pegaptanib in 40 patients with early onset of AMD....Lancet publishes proactive study: Diabetes treatment reduces risk of heart attacks & strokes
...ive study was also designed to further examine the safety of ACTOS in this high-risk patient group. The resu...orted in this study were consistent with the known safety profile. Known side effects of ACTOS, including weight gain, oedema, non-serious hypoglycaemia and h...Sports utility vehicles should carry health warnings, say experts
...proach from public health, transportation and road safety agencies to address this growing threat. Among roa...UVs to pedestrians is an emerging and real traffic safety challenge in the developed world, they conclude....NSAIDs show promise in preventing mouth cancer but pose heart risk
...isease as well as oral cancer, and implement other safety measures such as excluding patients with cardiovascular disease or specific risk factors of cardiovascular disease. Over the next few years, these trials will determine whether NSAIDs can reduce the devastating effect of oral cancer on patients, thei...UK government's privatisation plans for the NHS put patient welfare at risk
...drug would be licensed without good data about its safety and efficacy. Yet Britain's health system is freely turned upside down without any reference to evidence or any plans to study the controlled effects of these reforms. This kind of haphazard policy-making risks the welfare of patients and the commitm...NIAID launches first Phase II trial of a 'global' HIV/AIDS vaccine
...erica, South America and the Caribbean to test the safety and immune response to the vaccine. The experiment...Details The HVTN 204 Phase II study will test the safety and ability of the vaccine to generate an immune response in 480 healthy, HIV-negative adults ages 1...No reason to fear very low LDL
...ican College of Cardiology. "There was no apparent safety concern for patients whose resultant LDL on intens...and other health issues. Rather than assessing the safety of statin treatment itself, this analysis looked at the effects of various levels of LDL by comparin...Radical surgery best option for most ovarian cancer patients with cancer in diaphragm
...ack of evidence of survival benefit, concerns over safety (related to complexity and length of the surgery) and lack of surgeon experience as justifications often given for not proceeding with diaphragmatic surgery in advanced ovarian cancer patients. This study provided strong evidence of survival benefit...Therapeutic vaccine for ovarian cancer in clinical trials
...tients already undergoing treatment, including the safety of the procedure and vaccine, is currently under way and is due for completion on schedule by December 2005. The analysis will provide information to the SAP and form the basis of its recommendation to Prima management to continue the ovarian cancer ...Trial demonstrates new drug's effectiveness against psoriasis
... rheumatoid arthritis and Crohn's disease, but its safety and effectiveness against psoriasis has been unclear until now. Professor Christopher Griffiths (University of Manchester, UK) and colleagues recruited 378 patients with moderate to severe psoriasis to intravenously receive infliximab or placebo at 0...New rheumatoid arthritis drug developed at UCSD promises improved treatment options
...o trials of dnaJP1 have not raised any significant safety concerns and offer an improved treatment option for patients with rheumatoid arthritis," said Albani. The next step, according to Albani, is to get approval and funding to move into Phase III clinical trials. "This is a very exciting and novel thera...Life insurance: Research reveals concerns over use of health information
...n to individuals and families at a time when state safety nets are thinning out. "There are also worries that new developments in bioinformation, especially around human genetics, could increase this social and financial divide." The researchers acknowledge that selling life insurance does depend on healt...New study results suggest better outcomes with the CYPHER Stent than brachytherapy
...on, a Johnson & Johnson company. "The efficacy and safety results from this study were significantly better ...Artery Lesions, or SISR trial, showed the superior safety profile of the CYPHER(r) Stent compared to intravascular brachytherapy in complex patients. The prim...Study finds new type of silicone implant offers more natural looking breasts, low complication rate
...es the likelihood of rippling and provides greater safety because, being more solid, the silicone may not es... 13 year after it restricted access to them due to safety concerns. In 1992, the FDA imposed a moratorium on the sale of silicone implants and saline implants...