Loss of stem cells correlates with premature aging in animal study
...at were exhausting their ability to renew tissues, says Eric J. Brown, PhD, Assistant Professor of Cancer ...of pools of cells that reside in each tissue type, says Brown. We accelerated the aging process by wiping out a large fraction of these cells prematurely, i...Research probes seniors' plans for end-of-life care
...ut these decisions or the factors that shape them, says University of Wisconsin-Madison sociologist Debora... patients to imagine their future state of health, says Carr. Her study suggests instead that having people recall a loved one's death and their feelings ...USC and Childrens Hospital Los Angeles both receive grants for stem cell facilities
...l in securing these most recent grants from CIRM," says Brian Henderson, M.D., dean of the Keck School of ...ls and space for pilot and collaborative research, says Martin Pera, Ph.D., director of USC's CSCRM. We are excited to be recognized for our dedication in a...Study identifies new regulator of fat metabolism
...cial properties when it comes to lipid metabolism, says Maratos-Flier. Diets that limit carbohydrates and eliminate transfats, and at the same time emphasize fiber and good fats, appear to be healthiest, especially among individuals who are predisposed to developing diabetes....USC researchers show that molecular markers predict tumor recurrence
...efit from adjuvant chemotherapy following surgery, says Georg Lurje M.D., research associate at the Keck S...sis pathway play a critical role in tumor relapse, says Heinz-Josef Lenz, M.D., professor of medicine at the Keck School and the principal investigator on t...Benefits of trastuzumab are lasting, reducing both HER2 + breast cancer deaths and recurrence
...tistical and clinical significance of the therapy, says Dr. Perez. The four-year data show a persistent ...n be managed in most cases, she says. Dr. Perez says that continuing follow-up is needed to continue to define the long-term benefit of using trastuzumab...U-M study finds lymphoma drug effective over long term
...rly effective when used as a frontline treatment," says Mark Kaminski, M.D., professor of internal medicine at the U-M Medical School. Kaminski will present these results June 4 at the American Society of Clinical Oncology annual meeting in Chicago. "These results compare quite favorably with those achi...After epilepsy surgery, quality of life related more to seizures than memory
...pted than these kinds of memory problems, which he says patients sometimes can pass off as everyday forgetfulness. For the study, 138 people who had surgery for temporal lobe epilepsy were followed for five years after surgery. A total of 56 percent of those were free of seizures after the surgery. Anot...Strengthening exercises may slow progression of ALS
...lo-Haas acknowledges the study group was small and says more research is needed....Gender impacts colorectal cancer progression
...ill benefit from specific chemotherapy treatments, says principal investigator Heinz-Josef Lenz, M.D., pro...fferent genes appear to be predictive for outcome, says Lenz. This is the very first study showing that molecular markers may be sex specific. There has b...Antipsychotic drugs increase risk of death in older people with dementia
...sons who are already insured." An editorial writer says the findings do not show that having health insura...ves health care (Editorial p. 814). But the writer says that many other studies in the past quarter century "provide convincing support that health insuranc...Blocking stress protein decreases Alzheimer's peptide in mice
...id beta levels in the spaces between brain cells," says senior author David Holtzman, M.D., the Andrew B. and Gretchen P. Jones Professor and head of the Department of Neurology. "But we didn't know based on those initial experiments if it was a chronic effect or a much more immediate effect. If it was mo...African-American men understimate risk of prostate cancer
...state cancer to delay the pursuit of a diagnosis," says Dale. "With this data, we can't say why the est...erstand the reasons for the overly low estimates," says Dale. "That would hopefully lead to greater attention to prostate cancer for those at highest risk s...Bias in statin trials, failure to control malaria, and more
... deaths of too many African children from malaria, says a team of health researchers from Burkina Faso and the University of Heidelberg. Bocar Kouyat (Centre National de Recherche et de la Formation au Paludisme, Ouagadougou, Burkina Faso) and colleagues show how this lack of coordination is preventing ...National Academies Advisory -- June 8 public briefing on LANL groundwater protection
...ne there during the Cold War. New Mexico state law says LANL must evaluate and, if necessary, remediate the contamination by 2015. The report -- PLANS AND PRACTICES FOR GROUNDWATER PROTECTION AT THE LOS ALAMOS NATIONAL LABORATORY -- will be released at a one-hour public briefing on Friday, June 8. DET...Aussie research goes global through new grants
...s to take their work to an international audience, says APHCRI Director Professor Nicholas Glasgow. The work being done in Australia is of tremendous interest to overseas audiences, and of course our research benefits from this global input, Professor Glasgow said. The scholarships give researchers star...Study finds difference in survival rates among white and black women with advanced breast cancer
...ommunity to see if we would find similar results," says Shaheena Dawood, M.D., a Susan G. Komen Fellow in .... It's more likely due to socio-economic factors," says Giordano, the study's senior author. "While SEER data does not code for treatment, we hypothesize th...MUHC-led international team identifies gene responsible for blindness in infants and children
...e potential to fast-track a cure for this disease, says lead investigator Dr. Robert Koenekoop, director o...al diseases and causes of blindness in the future, says Dr. Koenekoop, who is also associate professor in Ophthalmology and Human Genetics at McGill Univers...Vorinostat shows anti-cancer activity in recurrent gliomas
...d interferes with the target pathways. Dr. Galanis says the researchers plan to expand this analysis to al...ell death and stopping tumor growth. Dr. Galanis says that study findings indicate that vorinostat by itself shows anti-cancer activity in glioblastoma mu...Nonhormonal drug reduces hot flashes in men treated for prostate cancer
...ication can be used to help some of our patients," says the studys lead investigator, Mayo Clinic oncologi...ow any of these drugs work to reduce hot flashes," says Dr. Loprinzi. Gabapentin (trade name Neurontin) was approved by the Food and Drug Administration (...