Tag: "scaffold" at medical news
Tissue engineering experts discuss orthopaedics applications
...tep is implanting the model in the body, where the scaffold
eventually degrades as the new organ or tissue integrates with the body. In addition to engineering tissues and organs, Atala and his team are also working to identify new sources of stem cells. Because these cells are unspecialized, they can acquire...
Nanotechnology's miniature answers to developing world's biggest problems
...ua University have begun clinical tests for a bone scaffold
based on nanotechnology which gradually disintegrates as the patient's damaged skeletal tissue heals. This application of nanotechnology is especially relevant for developing countries, where the number of skeletal injuries resulting from road traffi...
Promising new West Nile therapy cures disease in mice
...ntibody that cripples the West Nile virus into the scaffold
of a human antibody. The monoclonal antibody was several hundred times more potent in cell culture tests than antibodies obtained from people who had recovered from West Nile virus infection....
Molecular change occurring during brain tumor progression also evident in breast cancer
...ane, and the membrane, in addition to serving as a scaffold
for cell attachment, regulates cell behavior, proliferation and migration. The laminin molecule is composed of three chains -- designated alpha (), beta (]) and gamma (^) -- that are linked together in various combinations to form 15 known isofor...
Georgetown cancer researchers develop high throughput method
...uction, CEMA arrays do not require a space-wasting scaffold
or frame but samples are instead bonded directly to each other," Rui says. "The statistical power inherent in the larger sample numbers of CEMA arrays are expected to strengthen the discovery of new diagnostic markers," LeBaron says. "Such markers wi...
New non-surgical approach showing great promise in the treatment of challenging brain aneurysms
...ling the aneurysm with coils. The stent works as a scaffold
preventing the coils from migrating out of the wide neck aneurysm. The body responds by forming a blood clot around the coils and new tissue growth around the stent strengthening the weak spot in the artery. A study by Lopes, published in the Januar...
Scientists use stem cells to grow cartilage
...e cells were then implanted in mice on a bioactive scaffold
for 35 days. When they removed the scaffold, the c...e. The team had previously developed the bioactive scaffold
which was used as a scaffold
to grow the stem cells on. Dr Anne Bishop, from Imperial College London...
Study confirms that stents releasing medication help keep heart bypass vein grafts open
...nt a tiny mesh tube is designed to function as a scaffold
to keep the vessel open. But conventional bare-metal stents have been prone to the formation of scar tissue and subsequent re-narrowing. Now a study conducted at Cedars-Sinai Medical Center's Cardiovascular Intervention Center confirms that newer gen...
An engineer, a dentist, a veterinarian build bone tissue
...l oral constructions could result if a more viable scaffold
material were used that was capable of faster and higher quality bone formation." Love and the team are looking at amorphous calcium phosphates (ACPs) as inorganic host materials in the rebuilding of tissue. ACPs, in the presence of cells that make b...
JCI table of contents: January 19, 2006
...via the regulation of formation of the fibronectin scaffold
by pro-angiogenic astrocytes. TITLE: Tlx acts as a pro-angiogenic switch by regulating extracellular assembly of fibronectin matrices in retinal astrocytes AUTHOR CONTACT: Akiyoshi Uemura RIKEN Center for Developmental Biology, Kobe, Japan Phone: 81...
Viral, gold nanoparticles can assemble themselves to potentially find and treat disease
... The system also can be adapted to form a flexible scaffold
that can carry drugs, genes or even cradle restorative stem cells. "Gold is a perfect metal to perform these different functions, and scientists have been trying to find a way to target such particles to specific organs or tissues, but it has been ex...
UCR researchers grow bone cells on carbon nanotubes
...ime, that bone cells can grow and proliferate on a scaffold
of carbon nanotubes. The paper, titled Bone Cell ...00 times finer than a human hair, are an excellent scaffold
for bone cells to grow on. "In the past scientists have been plagued by toxicity issues when combin...
No-hands origami: New DNA self-assembly makes more complex structures, more easily
...s simple because it starts with a single, complete scaffold
one strand of viral DNA and uses short, complementary strands as staples to fold and keep the scaffold
in place. In Rothemunds one-pot approach, "the scaffold
is already perfect; all the information is t...
Wake Forest physician reports first human recipients of laboratory-grown organs
...to patients' original bladders during surgery. The scaffold
was designed to degrade as the bladder tissue integrated with the body. Testing showed that the engineered bladders functioned as well as bladders that are repaired with intestine tissue, but with none of the ill effects. "We have shown that regenera...
Scientists report success implanting tissue-engineered bladders into humans
...en placed onto a specially designed bladder-shaped scaffold
and left to grow for seven to eight weeks. The researchers surgically attached the engineered bladder to the patient's own bladder and followed progress for 2-5 years. They found that bladder function improved without any of the ill effects associate...
Factor stimulates cartilage growth from stem cells
...bohydrate known as alginate. The three-dimensional scaffold
provided by the alginate spheres promotes differentiation of treated hADAS cells into cartilage tissue. Interestingly, the Duke team also found that hADAS cells comprise a distinct lineage of stem cells. Other researchers have found that a certain ty...
Bioactive cement scaffold may improve bone grafts
...a method for making scaffolds for bone tissue. The scaffold
is seeded with a patient's own cells and is formed...olve when exposed to the body's fluids, creating a scaffold
that is filled by the now released bone cells. The cement, a calcium phosphate material, is strength...
Microscopic scaffolding offers a 'simple' solution to treating skin injuries
A revolutionary dissolvable scaffold
for growing new areas of skin could provide a safe...ally grow over it. When placed over the wound, the scaffold
dissolves harmlessly over 6 to 8 weeks, leaving the patient's skin cells behind. This new approach...
Dental stem cells have been characterized for tooth tissue engineering
...n and characterization of dental cell populations, scaffold
materials, and design that can be most effectively used for tooth tissue engineering applications. Hoechst dye profiling and immuno-sorting methods were used to generate enriched clonal dental stem cell (DSC) lines. Expanded DSC and non-DSC lines ar...
Penn researchers find Lou Gehrig's, FTD disease protein
...he transcription of the genetic code and also as a scaffold
protein for another motor neuron protein. The discovery that TDP-43 is the disease protein in the most common form of FTD and ALS will drive renewed efforts to discover more effective treatments for these otherwise lethal diseases....