Study supports activity of GEMZAR in the treatment of early-stage breast cancer
...ponent of the study. Patients received a first sequence of epirubicin and cyclophosphamide (90/600 mg/m2) for three cycles followed by a second sequence of paclitaxel and GEMZAR (150/2500 mg/m2) for six cycles. Treatment was administered on day one, eve...Mercury's link to heart disease begins in blood vessel walls
... The activation of the enzyme involves a complex sequence of events in the cell membranes that in turn releases phosphatidic acid, which can damage cells in the vessel lining called endothelial cells and is believed to contribute to vascular disorders. To further test the enzyme's role in blood vessel ...Possible new breast cancer gene
... but lack BRCA1 and BRCA2 mutations, have any gene sequence changes in Rap80."...New study in Sleep finds a high level of negativity towards judicial sleepiness
...ny and legal arguments. The Daily Telegraph, in a sequence of investigative articles, reported a lengthy list of Judge Dodds sleep episodes between 2002-2004 that appeared to affect court proceedings. In late 2004, Judge Dodd obtained a medical consultation regarding his sleepiness, was diagnosed with obstr...Green tea compound suppresses factors causing cartilage, bone destruction in arthritis
... When untreated cells were stimulated with IL-1, a sequence of molecular events occurred that resulted in production of the bone-destructive molecules. But the scientists found that pre-incubation with EGCG was capable of blocking the production of these molecules in a dose-dependent manner. Furthermore, EGCG...Green tea compound may be a therapy for people with rheumatoid arthritis
... When untreated cells were stimulated with IL-1, a sequence of molecular events occurred that resulted in production of the bone-destructive molecules. But the scientists found that pre-incubation with EGCG was capable of inhibiting the production of these molecules. EGCG also inhibited the production of pros...Scientists find missing link to understand how plants make vitamin C
...archer Tara Gomez in Clarkes UCLA laboratory. The sequence of the gene suggested that it is related to a family of genes altered in cancer, termed HIT genes, that Brenner studies at Dartmouth. Collaboration between the two laboratories revealed similarity of the worm gene to the product of the VTC2 gene of...Researchers discover gene crucial for nerve cell insulation
...uropathy. "The researchers have deciphered a key sequence essential to the assembly of myelin," said Duane A...l neuropathies, Dr. Svaren said. Ultimately, the sequence of activating genes "switches on" the Schwann cell, which wraps the nerve axon, the arm-like project...Wired for sound: How the brain senses visual illusions
...de is that the illusion depends on a rapidly timed sequence of interactions between the auditory and visual cortical areas." "This is part of a set of new findings by scientists in the field that show how integration of multiple sensations can happen much more rapidly than we thought before," said Mishra. ...'The eyes have it' -- Autism research yields surprising results
...pression, or animated and expressive. By showing a sequence of different combinations, they were able to gauge which aspects of the face were used by the autistic children to read someones mental state and how successful they were. In the second experiment, the 18 autistic children involved were as success...Research agreement to advance new imaging technology
...nd PET scanners reconstruct images by converting a sequence of two-dimensional images which are captured by a receptor as it rotates around the patient into a three dimensional image. While these technologies have provided doctors an invaluable view into the human body, the images often contain flaws. Ra...A new focus for health care reform -- realigning competition around patient value
...tients comes from the overall effect of the entire sequence of activities, not from any individual service." The authors note that physicians are beginning to organize care around medical conditions and are forming institutes, centers, and other types of integrated structures that bring needed specialties and...Genetic pathways to curable and incurable forms of pancreatic cancer identified
...ancer, researchers have discovered that a specific sequence of otherwise common genetic mutations is responsib...ssue of the journal Cancer Cell that explains this sequence and details why the cells behave differently. "Although at their end stage the two different route...Disposable sensor uses DNA to detect hazardous uranium ions
...est threat to human life. To search for the unique sequence of DNA that could distinguish uranyl from other me... to 1,000 trillion molecules), amplify the desired sequence by the polymerase chain reaction, and introduce mutations to improve performance. Lu, with collabora...Brain studies reveal the mechanisms of the voluntary control of visual attention
...ists at Duke University have mapped the timing and sequence of neural activations that unfold in the brain whe...signal. But "little is known about the timing and sequence of activations within this frontal-parietal network and their temporal relationship to any such bias...Operations research pioneer outlines ways to make kidney transplant allocation more equitable
...o accept is. In essence, Zenios' model creates a sequence of queues for kidneys of various grades and, within these queues, organs that become available are allocated based on waiting time. This contrasts with the present allocation system, determined by the United Network of Organ Sharing (UNOS), whereby k...Gene chip discovery may lead to individualized treatment for 5 hereditary liver diseases
...to screen mutations (a permanent change in the DNA sequence that makes up a gene) in five genes using only one milliliter, or less than a half of a teaspoon, of blood. Gene chips contain several thousand small fragments of DNA on a small piece of glass. Incubation of these chips with the patient's DNA sample ...NIAID media availability: Examining genetic variability of malaria parasite offers insight
... (NIH), reports the results of a massive effort to sequence and compare complete or partial genomes of 54 different samples from around the globe of the most deadly type of malaria parasite, Plasmodium falciparum. The sequencing, carried out in part at NIAID's Microbial Sequencing Center, has revealed nearly ...'GreeneChip' -- New diagnostic tool that rapidly and accurately identifies multiple pathogens
...eneChip features include a comprehensive microbial sequence database that integrates previously distinct reserves of information about pathogensfor every entry of a pathogen and its properties, the GreeneChip contains a correlate of its genetic makeup. GreeneChip performance was initially tested by using ......ria, and translating Plasmodium falciparum genomic sequence data for practical application. The Fellowship will allow Dr Doolan to resume her academic career in Australia after studying in the US. Pfizer Australia has allocated $11 million in funding to Australian scientists since the Pfizer Australia R...